公开(公告)号：US20100136537A1

公开(公告)日：2010-06-03

申请号：US12445031

申请日：2007-10-10

申请人： Anand Swaroop ,  Masayuki Akimoto ,  Alan Mears ,  Hong Cheng ,  Edwin C.T. Oh

发明人： Anand Swaroop ,  Masayuki Akimoto ,  Alan Mears ,  Hong Cheng ,  Edwin C.T. Oh

IPC分类号： C12Q1/68 ,  C12N5/07 ,  C12N15/00

CPC分类号： C12N5/062 ,  A01K67/0275 ,  A01K2217/05 ,  A01K2227/105 ,  A01K2267/03 ,  A61K35/44 ,  C12N15/8509 ,  C12N2501/385 ,  C12N2830/008

摘要： The present invention relates to photoreceptor cells. In particular, the present invention provides photoreceptor cells comprising heterologous nucleic acid sequences and transgenic animals comprising the same. The present invention also provides photoreceptor precursor cells (e.g., rod photoreceptor precursor cells), and methods of identifying, characterizing, isolating and utilizing the same. Compositions and methods of the present invention find use in, among other things, research, clinical, diagnostic, drug discovery, and therapeutic applications.

摘要翻译： 本发明涉及感光细胞。 特别地，本发明提供包含异源核酸序列的感光细胞和包含其的转基因动物。 本发明还提供感光体前体细胞（例如，棒状感光体前体细胞），以及识别，表征，分离和利用该感光体前体细胞的方法。 本发明的组合物和方法尤其可用于研究，临床，诊断，药物发现和治疗应用。

公开(公告)号：US06253655B1

公开(公告)日：2001-07-03

申请号：US09251736

申请日：1999-02-18

申请人： Fielder Stanton Lyons ,  Jeffrey Alan Mears

发明人： Fielder Stanton Lyons ,  Jeffrey Alan Mears

IPC分类号： F41H502

CPC分类号： F41H5/0428

摘要： A lightweight armor having a durable spall cover for suppressing debris that would otherwise be ejected from the armor as a result of the impact of a projectile or missile on the lightweight armor. In addition, the invention allows a ceramic or ceramic-based composite armor panels to be dropped onto a concrete surface without sustaining any damage to the ceramic tile. A preferred embodiment of the present invention is a laminate comprising a polymer sheet outer layer, a flexible foam sheet or flexible honeycomb inner layer, a ceramic-based armor plate, and a fiber-reinforced plastic laminate backing, as well as adhesive layers bonding each of the main layers to its adjacent layer or layers. When an object impacts the polymer sheet outer layer, the impact force is distributed by the polymer sheet outer layer to the flexible foam inner layer that in turn absorbs some of the kinetic energy. When a ballistic projectile such as a bullet strikes the polymer sheet, it perforates the polymer sheet and is defeated by the armor plate. The flexible foam inner layer and the polymer sheet outer layer would also suppress the resultant spall from ejecting out of the armor.

摘要翻译： 一种轻型装甲，具有耐用的分离盖，用于抑制由于射弹或导弹对轻型装甲的冲击而将从装甲弹出的碎片。 此外，本发明允许将陶瓷或陶瓷基复合材料护板落在混凝土表面上，而不会对瓷砖造成任何损坏。 本发明的优选实施方案是包含聚合物片外层，柔性泡沫片或柔性蜂窝内层，陶瓷基铠装板和纤维增强塑料层合物背衬的层压材料，以及粘合每个 的主层到其相邻的层或层。 当物体撞击聚合物片材外层时，冲击力由聚合物片材外层分配到柔性泡沫内层，柔性泡沫内层又吸收一些动能。 当弹丸弹如子弹撞击聚合物片时，它穿透聚合物片并被装甲板击倒。 柔性泡沫内层和聚合物片外层也将抑制所得到的碎屑从装甲中喷出。