Predictive biomarkers in cancer therapy
    1.
    发明授权
    Predictive biomarkers in cancer therapy 有权
    癌症治疗中的预测性生物标志物

    公开(公告)号:US07794960B2

    公开(公告)日:2010-09-14

    申请号:US11569980

    申请日:2005-05-12

    IPC分类号: G01N33/53

    CPC分类号: G01N33/57415

    摘要: The use of various biomarkers to assess a subject's suitability for treatment with a EGFR/ErbB2 kinase inhibitor for a solid tumor are described. The biomarkers include TGFalpha, pS6, IGF-1R and levels of apoptosis occurring in tumor tissue.

    摘要翻译: 描述了使用各种生物标志物评估受试者对用于实体瘤的EGFR / ErbB2激酶抑制剂治疗的适用性。 生物标志物包括TGFα,pS6,IGF-1R和凋亡发生在肿瘤组织中的水平。

    System and method for testing video devices using a test fixture
    2.
    发明授权
    System and method for testing video devices using a test fixture 有权
    使用测试夹具测试视频设备的系统和方法

    公开(公告)号:US06961885B2

    公开(公告)日:2005-11-01

    申请号:US09994261

    申请日:2001-11-26

    IPC分类号: G01R31/3185 G01R31/28

    摘要: Systems and methods are provided for testing a device. A test fixture is provided for interfacing a device with a host system for generating tests to be run on the device. The device is placed in a scan-test mode, according to a built-in self-test of the device. A scan clock signal and scan pattern are provided to allow scan-tests to be run on the device. If the device passes the scan test, the device is placed in a real-time test mode. At-speed tests may then be run on the device to provide a robust test and identify portions of the device that may be faulty.

    摘要翻译: 提供了用于测试设备的系统和方法。 提供了一种测试夹具,用于将设备与主机系统连接起来,用于生成要在设备上运行的测试。 根据设备的内置自检,该设备处于扫描测试模式。 提供扫描时钟信号和扫描模式以允许在设备上运行扫描测试。 如果设备通过扫描测试,设备将进入实时测试模式。 然后可以在设备上运行速度测试以提供鲁棒的测试并且识别可能有故障的设备的部分。

    System for testing multiple devices on a single system and method thereof
    3.
    发明授权
    System for testing multiple devices on a single system and method thereof 失效
    用于在单个系统上测试多个设备的系统及其方法

    公开(公告)号:US06880116B2

    公开(公告)日:2005-04-12

    申请号:US09995312

    申请日:2001-11-27

    IPC分类号: G01R31/319 G11C29/00

    CPC分类号: G01R31/31905 G01R31/31926

    摘要: A system and method for testing multiple components using a single host system is shown and described. A host system with a single advanced graphics port (AGP) is used to generate commands of a test routine to test a particular type of AGP processing component. A test fixture interfaces to the AGP port of the host system and provides the commands to each of a plurality of test components. The test components process the commands concurrently, generating results. The test fixture receives each of the results in turn and provides the results to the host system, allowing the host system to determine if the test components are functioning within particular parameters. The test fixture provides an interface to allow several test components to be tested as AGP master devices, over a single AGP port on the host system.

    摘要翻译: 显示和描述了使用单个主机系统测试多个组件的系统和方法。 具有单个高级图形端口(AGP)的主机系统用于生成测试例程的命令,以测试特定类型的AGP处理组件。 测试夹具连接到主机系统的AGP端口,并向多个测试组件中的每一个提供命令。 测试组件同时处理命令,生成结果。 测试夹具依次接收每个结果,并将结果提供给主机系统,允许主机系统确定测试组件是否在特定参数内运行。 测试夹具提供了一个接口,允许通过主机系统上的单个AGP端口将多个测试组件作为AGP主设备进行测试。

    Diagnostic markers of cardiovascular illness and methods of use thereof
    4.
    发明申请
    Diagnostic markers of cardiovascular illness and methods of use thereof 审中-公开
    心血管疾病的诊断标记及其使用方法

    公开(公告)号:US20050181386A1

    公开(公告)日:2005-08-18

    申请号:US10948834

    申请日:2004-09-22

    摘要: The present invention relates to methods for the diagnosis and evaluation of cardiovascular illness, particularly stroke, myocardial and other cardiovascular damage damage, hypertension treatment. In particular, patient test samples are analyzed for the presence and amount of members of a panel of markers comprising one or more specific markers for cardiovascular illness or hypertension treatment and one or more non-specific markers for cardiovascular illness or hypertension treatment. A variety of markers are disclosed for assembling a panel of markers for such diagnosis and evaluation. Algorithms for determining proper treatment are disclosed. A diagnostic kit for a panel of said markers is disclosed. In various aspects, the invention provides methods for the early detection and differentiation of cardiovascular illness or hypertension treatment. Invention methods provide rapid, sensitive and specific assays that can greatly increase the number of patients that can receive beneficial treatment and therapy, reduce the costs associated with incorrect diagnosis, and provide important information about the prognosis of the patient.

    摘要翻译: 本发明涉及用于诊断和评价心血管疾病,特别是中风,心肌和其他心血管损伤损伤,高血压治疗的方法。 特别地,分析患者测试样品中包含一种或多种用于心血管疾病或高血压治疗的特异性标志物的标志物组的成员的存在和量,以及用于心血管疾病或高血压治疗的一种或多种非特异性标志物。 公开了用于组装用于这种诊断和评价的标记物的各种标记。 公开了用于确定适当处理的算法。 公开了一种用于所述标记物组的诊断试剂盒。 在各方面,本发明提供了用于心血管疾病或高血压治疗的早期检测和分化的方法。 本发明的方法提供快速,灵敏和特异性的测定,其可以大大增加可以接受有益治疗和治疗的患者数量,降低与错误诊断相关的成本,并提供有关患者预后的重要信息。

    Method and apparatus for self-testing of a multimedia subsystem
    5.
    发明授权
    Method and apparatus for self-testing of a multimedia subsystem 失效
    多媒体子系统自检的方法和装置

    公开(公告)号:US5920340A

    公开(公告)日:1999-07-06

    申请号:US900818

    申请日:1997-07-25

    IPC分类号: H04N17/04

    CPC分类号: H04N17/045

    摘要: A method and apparatus for self-testing of a multimedia subsystem is accomplished by retrieving a pattern from a first section of memory, where the retrieving is done by a video graphics circuit. Having retrieved the pattern, the video graphics circuit provides it to a video capture circuit via a television encoder. Upon receiving the pattern, the video capture board generates a capture pattern therefrom. The capture pattern is then provided by the video capture circuit to memory via the video graphics circuit. Once the video capture pattern is stored in memory, the capture pattern is compared with the original pattern. When the comparison is favorable, the video capture circuit, the television tuner, and the interconnecting paths have passed testing.

    摘要翻译: 用于多媒体子系统的自检的方法和装置通过从存储器的第一部分检索模式来实现,其中检索由视频图形电路完成。 在检索到图案之后,视频图形电路经由电视编码器将其提供给视频采集电路。 在接收到图案时,视频捕获板从其生成捕获模式。 捕捉模式然后由视频捕获电路通过视频图形电路提供给存储器。 一旦将视频捕获模式存储在存储器中,捕获模式将与原始模式进行比较。 当比较有利时,视频采集电路,电视调谐器和互连路径已通过测试。

    Predicitive biomarkers in cancer therapy
    6.
    发明申请
    Predicitive biomarkers in cancer therapy 有权
    癌症治疗中的预测性生物标志物

    公开(公告)号:US20070190583A1

    公开(公告)日:2007-08-16

    申请号:US11569980

    申请日:2005-05-12

    IPC分类号: G01N33/574

    CPC分类号: G01N33/57415

    摘要: The use of various biomarkers to assess a subject's suitability for treatment with a EGFR/ErbB2 kinase inhibitor for a solid tumor are described. The biomarkers include TGFalpha, pS6, IGF-1R and levels of apoptosis occurring in tumor tissue.

    摘要翻译: 描述了使用各种生物标志物评估受试者对用于实体瘤的EGFR / ErbB2激酶抑制剂治疗的适用性。 生物标志物包括TGFα,pS6,IGF-1R和凋亡发生在肿瘤组织中的水平。

    Diagnostic markers of hypertension and methods of use thereof
    7.
    发明申请
    Diagnostic markers of hypertension and methods of use thereof 审中-公开
    高血压的诊断标记及其使用方法

    公开(公告)号:US20070092888A1

    公开(公告)日:2007-04-26

    申请号:US11435051

    申请日:2006-05-15

    IPC分类号: C12Q1/68 G06F19/00

    摘要: The present invention relates to methods for the diagnosis and evaluation of cardiovascular illness, particularly hypertension treatment. In particular, patient test samples are analyzed for the presence and amount of members of a panel of markers comprising one or more specific markers for hypertension treatment and one or more non-specific markers for hypertension treatment. A variety of markers are disclosed for assembling a panel of markers for such diagnosis and evaluation. Algorithms for determining proper treatment are disclosed. A diagnostic kit for a panel of said markers is disclosed. In various aspects, the invention provides methods for the early detection and differentiation of hypertension treatment. Invention methods provide rapid, sensitive and specific assays that can greatly increase the number of patients that can receive beneficial treatment and therapy, reduce the costs associated with incorrect diagnosis, and provide important information about the prognosis of the patient.

    摘要翻译: 本发明涉及用于诊断和评估心血管疾病,特别是高血压治疗的方法。 特别地,分析患者测试样品中含有一种或多种用于高血压治疗的特异性标志物和一种或多种用于高血压治疗的非特异性标志物的标记组的成员的存在和量。 公开了用于组装用于这种诊断和评价的标记物的各种标记。 公开了用于确定适当处理的算法。 公开了一种用于所述标记物组的诊断试剂盒。 在各方面,本发明提供了用于早期检测和分化高血压治疗的方法。 本发明的方法提供快速,灵敏和特异性的测定,其可以大大增加可以接受有益治疗和治疗的患者数量,降低与错误诊断相关的成本,并提供有关患者预后的重要信息。

    Method and apparatus for application's specific testing of assembled
circuits
    8.
    发明授权
    Method and apparatus for application's specific testing of assembled circuits 有权
    用于组装电路应用特定测试的方法和装置

    公开(公告)号:US6038520A

    公开(公告)日:2000-03-14

    申请号:US166207

    申请日:1998-10-02

    CPC分类号: G01R31/31903

    摘要: A method and apparatus for testing specific assembled circuits begins by configuring a plurality of applications specific testing entities to test assembled circuits, where the configuring is based on the types of assembled circuits being tested. Next, a specific assembled circuit testing program is provided to the corresponding application specific testing entity based on the type of assembled circuits it is testing. In addition to providing the testing programs to the testing entities, programming instructions are provided to a programmable handler to pick and place the appropriate assembled circuits with the corresponding applications specific testing entities. When the testing of a particular assembled circuit is complete, a test complete indication is provided. When the test complete indication is received by the host, programming instructions are provided to the programmable handler to remove the integrated circuit from the testing entity and place another integrated circuit in the proximity of the testing entity for subsequent testing.

    摘要翻译: 用于测试特定组装电路的方法和装置开始于通过配置多个应用特定的测试实体来测试组装的电路,其中组态基于被测试的组合电路的类型。 接下来,基于其正在测试的组合电路的类型,将特定的组装电路测试程序提供给相应的应用特定测试实体。 除了向测试实体提供测试程序外,还向可编程处理程序提供编程指令,以便将相应的应用程序特定测试实体的合适的组合电路进行选择和放置。 当特定组装电路的测试完成时,提供测试完成指示。 当主机接收到测试完成指示时,向可编程处理程序提供编程指令,以从测试实体中移除集成电路,并将另一个集成电路放置在测试实体附近以供后续测试。