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公开(公告)号:US20130189303A1
公开(公告)日:2013-07-25
申请号:US13559940
申请日:2012-07-27
申请人: Yan Zhou , Aleksandar Masic
发明人: Yan Zhou , Aleksandar Masic
IPC分类号: A61K39/145
CPC分类号: A61K39/145 , A61K39/12 , A61K2039/5254 , A61K2039/544 , A61K2039/552 , A61K2039/70 , C12N7/00 , C12N2760/16121 , C12N2760/16134 , C12N2760/16151 , C12N2760/16162 , C12N2760/16171 , C12N2799/025
摘要: Recombinant, chimeric porcine influenza viruses are disclosed that include hemagglutinin segments from more than one influenza virus subtype. Also described are methods of producing the recombinant influenza viruses, immunogenic compositions comprising the recombinant influenza viruses, methods of stimulating an immune response against influenza virus, and methods of treating and preventing influenza virus infection.
摘要翻译: 公开了重组的嵌合型猪流感病毒,其包括来自多于一种流感病毒亚型的血凝素区段。 还描述了生产重组流感病毒的方法,包含重组流感病毒的免疫原性组合物,刺激针对流感病毒的免疫应答的方法,以及治疗和预防流感病毒感染的方法。