Extended release formulation of pramipexole dihydrochloride
    7.
    发明申请
    Extended release formulation of pramipexole dihydrochloride 审中-公开
    普拉克索二盐酸盐的延长释放制剂

    公开(公告)号:US20060110454A1

    公开(公告)日:2006-05-25

    申请号:US11260066

    申请日:2005-10-27

    CPC classification number: A61K9/5078 A61K9/2081 A61K9/5047 A61K31/428

    Abstract: An extended release composition of Pramipexole or a pharmaceutical acceptable salt thereof, wherein the active agent is coated on a non pareil inert core, the drug loaded core is further coated with a polymeric layer which enables the release of the active agent over an extended period and optionally the extended release pellets being further blended with suitable excipients and compressed into a multi unit tablet and processes for the preparation of the said composition.

    Abstract translation: 普拉克索或其药学上可接受的盐的延长释放组合物,其中所述活性剂涂覆在非帕里尔惰性核心上,所述药物负载核心还进一步涂覆聚合物层,所述聚合物层能够在长时间内释放活性剂, 任选地,延长释放丸粒进一步与合适的赋形剂混合并压制成多单位片剂并制备所述组合物。

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