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公开(公告)号：US07686837B2
公开(公告)日：2010-03-30
申请号：US10544323
申请日：2003-12-31
IPC分类号： A61B17/58
CPC分类号： A61B17/8047 , A61B17/863
摘要： The invention relates to an implantable orthopaedic device comprising a load-bearing element, such as a bone plate, for fixing elements, such as bone screws, that can be oriented polyaxially. The load-bearing element is equipped with at least one opening for the passage of the fixing elements. A two part insert is provided in the opening, the insert having an external form that complements the internal form of the receiving opening and permits the polyaxial rotation of the insert in the opening. The insert is equipped with a central bore for receiving the body of the fixing element. The first insert element part has a central inner hollow chamber, into which the second insert element part can be introduced. The first insert element is flexible or has at least one slit, in such a way that when the two insert elements are displaced axially in relation to one another, the first insert element in the plate can be expanded at least partially in order to block the position and alignment of the fixing element in the device in a polyaxial manner.
摘要翻译： 本发明涉及一种可植入矫形装置，其包括用于诸如骨螺钉的固定元件（例如骨板）的承载元件，其可以被多轴定向。 承载元件配备有用于固定元件通过的至少一个开口。 两个部分的插入件设置在开口中，插入件具有补充接收开口的内部形式的外部形式并且允许插入件在开口中的多轴旋转。 插入件配备有用于接收固定元件的主体的中心孔。 第一插入元件部分具有中心内部中空室，可以将第二插入元件部分引入该中空室。 第一插入元件是柔性的或具有至少一个狭缝，以这样的方式，当两个插入元件相对于彼此轴向移位时，板中的第一插入元件可以至少部分地膨胀以阻止 固定元件以多轴方式在装置中的位置和对准。
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公开(公告)号：US20070168157A1
公开(公告)日：2007-07-19
申请号：US10567198
申请日：2004-08-09
申请人： Alexander Khibnik , Mauro Atalla , Alan Finn , Mark Davis , Jun Ma , James Cycon , Peter Horbury , Andreas Bernhard
发明人： Alexander Khibnik , Mauro Atalla , Alan Finn , Mark Davis , Jun Ma , James Cycon , Peter Horbury , Andreas Bernhard
IPC分类号： G06F15/00
CPC分类号： G05B23/0221 , G05B13/04 , G05B17/02 , G05B19/4065 , G05B2219/37249
摘要： A method and system estimates a desired output signal waveform based on measured state parameters. A model training step generates a model by empirically obtaining measured signal waveforms corresponding to measured state parameters. Features, such as mode shapes and mode amplitudes, are extracted from the measured signals and stored in an estimation model along with coefficients of the model that correlate measured state parameters with the mode amplitudes. During part operation, the state parameters measured during operation are entered into the estimation model to obtain estimated features in a estimated signal waveform. The estimated features are then used to synthesize the estimated signal reflecting the actual operation of the operating part. The estimation model therefore allows estimation of an entire signal waveform from the state parameters.
摘要翻译： 方法和系统基于测量的状态参数来估计期望的输出信号波形。 模型训练步骤通过经验获得对应于测量状态参数的测量信号波形来生成模型。 从测量信号中提取特征，例如模式形状和模式振幅，并将其与模型的系数一起存储在估计模型中，并将测量的状态参数与模式幅度相关联。 在部分操作期间，将运行期间测量的状态参数输入到估计模型中以获得估计信号波形中的估计特征。 然后使用估计的特征来合成反映操作部件的实际操作的估计信号。 因此，估计模型允许从状态参数估计整个信号波形。
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3.发明申请公开(公告)号：US20060177264A1
公开(公告)日：2006-08-10
申请号：US11119574
申请日：2005-05-02
IPC分类号： F16B7/04
CPC分类号： A61B17/66 , A61B17/6458 , A61B17/6491 , Y10T403/7062
摘要： An external fixation device for the extension of the distance between two clamping members of an external fixator has a central internal rod and an outer hollow housing. The internal rod is movable axially. One end of the internal rod projects over the one end of the housing, and serves to fix the one clamping member. An adjusting member is provided disposed at the other end of the housing and is connected with internal rod and/or the outer hollow housing, whereby the axial position of the interior shaft can be adjusted in relation to the housing by means of rotation of the adjusting member. Furthermore, an adjusting knob is provided that can be detachably attached to the adjusting member with an essentially positive fit.
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公开(公告)号：US06547791B1
公开(公告)日：2003-04-15
申请号：US09744544
申请日：2001-05-29
申请人： Volker Bühren , Thomas Wahl , Lukas Sutter , Andreas Bernhard , Gunther O. Hofmann , Oliver Gonschorek
发明人： Volker Bühren , Thomas Wahl , Lukas Sutter , Andreas Bernhard , Gunther O. Hofmann , Oliver Gonschorek
IPC分类号： A61B1772
CPC分类号： A61B17/7208
摘要： The tibia nail comprises a tube including a continuous longitudinal bore and includes a proximal anchoring portion with several cross-bores, an adjoining connecting portion which is flexurally resilient in an anterior and posterior direction, a shank adjoining it, and a distal anchoring portion. The anchoring portion is bent away with respect to the shank and has an elongated hole through which a locking screw may be placed. The tibia may be compressed by means of a compression screw inserted into a longitudinal threaded bore. The tibia nail enables retrograde implantation, which has been considered to be impossible for the tibia up to now.
摘要翻译： 胫骨钉包括包括连续纵向孔的管，并且包括具有多个十字孔的近侧锚定部分，在前后方向上具有弯曲弹性的邻接连接部分，与其相邻的柄部以及远侧锚固部分。 锚定部分相对于柄部弯曲离开，并且具有长孔，锁定螺钉可以通过该细长孔布置。 胫骨可以通过插入纵向螺纹孔中的压紧螺钉来压缩。 胫骨指甲使逆行植入，迄今为止被认为是不可能的胫骨。
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公开(公告)号：US20230340086A1
公开(公告)日：2023-10-26
申请号：US17596652
申请日：2019-06-19
CPC分类号： C07K16/1203 , A61K45/06 , A61P31/04 , A61K2039/55566
摘要： Provided herein are antibodies, such as immunoglobulins Y (IgY) antibodies that inhibit beta-lactamase activity, e.g., TEM-1 beta-lactamase, as well as related compositions and methods of use thereof to treat infections by lactam-based antibiotic bacteria that produce beta-lactamase that can degrade antibiotics.
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公开(公告)号：US08892983B2
公开(公告)日：2014-11-18
申请号：US12612674
申请日：2009-11-04
CPC分类号： H03M13/09 , H03M13/611 , H03M13/6522 , H03M13/6527 , H04L1/0041 , H04L1/0076 , H04L1/0084
摘要： A method processes a data packet in a first sequence of disjoint original segments of the same length. The method includes modifying a first of the original segments of the first sequence by modifying one or more symbols therein. A start of the data packet is located in the first of the original segments and is positioned after a first digital data symbol therein. The method also includes modifying a last of the original segments of the first sequence by modifying one or more digital data symbols therein. An end of the data packet is located in the last of the original segments and is located before the last digital data symbol therein. The method also includes determining a remainder sequence by effectively performing a polynomial division on a second sequence of disjoint segments that are derived from the first sequence. Each segment of the second sequence corresponds to and is derived from one of the original segments of the first sequence. The segments of the second sequence have the length of the original segments of the first sequence. A first of the derived segments of the second sequence is the modified first of the original segments. A last of the derived segments of the second sequence is derived from the modified last of the original segments.
摘要翻译： 一种方法处理相同长度的不相交的原始段的第一序列中的数据分组。 该方法包括通过修改其中的一个或多个符号来修改第一序列的第一个原始段。 数据分组的开始位于第一个原始分段中，并且位于其中的第一数字数据符号之后。 该方法还包括通过修改其中的一个或多个数字数据符号来修改第一序列的最后一个原始段。 数据包的结尾位于最后的原始段中，并且位于其中的最后一个数字数据符号之前。 该方法还包括通过有效地执行从第一序列导出的第二不相交段序列上的多项式除法来确定余数序列。 第二序列的每个片段对应于并且从第一序列的原始片段之一导出。 第二序列的片段具有第一序列的原始片段的长度。 第二个序列的导出段中的第一个是原始段的修改的第一个段。 第二个序列的最后导出段是从修改的最后一个原始段导出的。
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7.发明授权Quick-release guide assembly for elements of or for an external fixation system 有权用于外部固定系统元件的快速释放导向组件公开(公告)号：US08353916B2
公开(公告)日：2013-01-15
申请号：US11439569
申请日：2006-05-23
CPC分类号： A61B17/1728 , A61B17/1746 , A61B2017/00464 , A61B2017/00473 , A61F2002/3401
摘要： A quick-release guide assembly for an external fixation system has a body with at least one hole and a handle portion with a handle bar. The device body comprises at least one extension having a first coupling portion. The handle comprises a complementary second coupling portion, wherein one coupling portion comprising a spring actuated locking pin, wherein an actuator knob is provided to release the locking pin. Therefore the coupling portion of the handle can be releasably attached to the guide body, enabling a quick change of device bodies having different oriented and arranged holes.
摘要翻译： 用于外部固定系统的快速释放引导组件具有至少一个孔的主体和具有把手的把手部分。 装置主体包括具有第一联接部分的至少一个延伸部。 手柄包括互补的第二联接部分，其中一个联接部分包括弹簧致动的锁定销，其中提供致动器旋钮以释放锁定销。 因此，手柄的连接部可以可释放地附接到引导体，能够快速改变具有不同取向和排列的孔的装置主体。
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公开(公告)号：US08043053B2
公开(公告)日：2011-10-25
申请号：US11962257
申请日：2007-12-21
申请人： Andreas Bernhard
发明人： Andreas Bernhard
IPC分类号： B64C3/52
CPC分类号： B64C27/615 , B64C2027/7288 , Y02T50/34
摘要： A trim tab assembly includes first and second shape memory alloy (SMA) actuators and a trim tab substrate which provide elastic/plastic locking in response to an induced strain actuation.
摘要翻译： 修剪翼片组件包括第一和第二形状记忆合金（SMA）致动器和修剪翼片基底，其响应于感应应变致动而提供弹性/塑性锁定。
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公开(公告)号：US20090162199A1
公开(公告)日：2009-06-25
申请号：US11962257
申请日：2007-12-21
申请人： Andreas Bernhard
发明人： Andreas Bernhard
IPC分类号： B64C3/52 , B64C27/58 , B64C27/615
CPC分类号： B64C27/615 , B64C2027/7288 , Y02T50/34
摘要： A trim tab assembly includes first and second shape memory alloy (SMA) actuators and a trim tab substrate which provide elastic/plastic locking in response to an induced strain actuation.
摘要翻译： 修剪翼片组件包括第一和第二形状记忆合金（SMA）致动器和修剪翼片基底，其响应于感应应变致动而提供弹性/塑性锁定。
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公开(公告)号：US07532988B2
公开(公告)日：2009-05-12
申请号：US10567198
申请日：2004-08-09
申请人： Alexander I. Khibnik , Mauro Jorge Atalla , Alan M. Finn , Mark W. Davis , Jun Ma , James Cycon , Peter F. Horbury , Andreas Bernhard
发明人： Alexander I. Khibnik , Mauro Jorge Atalla , Alan M. Finn , Mark W. Davis , Jun Ma , James Cycon , Peter F. Horbury , Andreas Bernhard
IPC分类号： G01R13/00
CPC分类号： G05B23/0221 , G05B13/04 , G05B17/02 , G05B19/4065 , G05B2219/37249
摘要： A method and system estimates a desired output signal waveform based on measured state parameters. A model training step generates a model by empirically obtaining measured signal waveforms corresponding to measured state parameters. Features, such as mode shapes and mode amplitudes, are extracted from the measured signals and stored in an estimation model along with coefficients of the model that correlate measured state parameters with the mode amplitudes. During part operation, the state parameters measured during operation are entered into the estimation model to obtain estimated features in a estimated signal waveform. The estimated features are then used to synthesize the estimated signal reflecting the actual operation of the operating part. The estimation model therefore allows estimation of an entire signal waveform from the state parameters.
摘要翻译： 方法和系统基于测量的状态参数来估计期望的输出信号波形。 模型训练步骤通过经验获得对应于测量状态参数的测量信号波形来生成模型。 从测量信号中提取特征，例如模式形状和模式振幅，并将其与模型的系数一起存储在估计模型中，并将测量的状态参数与模式幅度相关联。 在部分操作期间，将运行期间测量的状态参数输入到估计模型中以获得估计信号波形中的估计特征。 然后使用估计的特征来合成反映操作部件的实际操作的估计信号。 因此，估计模型允许从状态参数估计整个信号波形。
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