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公开(公告)号：US07034045B1
公开(公告)日：2006-04-25
申请号：US09958262
申请日：2000-04-17
申请人： David Michael Bender , Buddy Eugene Cantrell , Andrew Hendley Fray , Winton Dennis Jones , William David Miller , David Mitchell , Richard Lee Simon , Hamideh Zarrinmayeh , Dennis Michael Zimmerman
发明人： David Michael Bender , Buddy Eugene Cantrell , Andrew Hendley Fray , Winton Dennis Jones , William David Miller , David Mitchell , Richard Lee Simon , Hamideh Zarrinmayeh , Dennis Michael Zimmerman
IPC分类号： A61K31/44 , A61K31/40 , A61K31/38 , A61K31/275 , A61K31/195
CPC分类号： C07D213/81 , C07C307/06 , C07C311/03 , C07C311/04 , C07C311/05 , C07C311/06 , C07C311/08 , C07C311/39 , C07D209/34 , C07D213/38 , C07D213/61 , C07D213/82 , C07D261/18 , C07D295/192 , C07D333/20 , C07D333/38
摘要： The present invention provides certain monofluoroalkyl derivatives useful for potentiating glutamate receptor function in a mammal and therefore, useful for treating a wide variety of conditions, such as psychiatric and neurological disorders.
摘要翻译： 本发明提供某些用于增强哺乳动物谷氨酸受体功能的单氟代烷基衍生物，因此可用于治疗各种各样的病症如精神病和神经障碍。
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公开(公告)号：US06803484B2
公开(公告)日：2004-10-12
申请号：US10746164
申请日：2003-12-24
IPC分类号： C07C31103
CPC分类号： C07C311/05
摘要： The present invention relates to a compound of formula (Ia) or a pharmaceutically acceptable salt thereof which is useful for the treatment of conditions associated with glutamate hypofunction, such as psychiatric and neurological disorders.
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公开(公告)号：US06358981B1
公开(公告)日：2002-03-19
申请号：US09744414
申请日：2001-01-23
申请人： Macklin Brian Arnold , David Michael Bender , Andrew Hendley Fray , Winton Dennis Jones , Paul Leslie Ornstein , Richard Lee Simon , Hamideh Zarrinmayeh , Dennis Michael Zimmerman
发明人： Macklin Brian Arnold , David Michael Bender , Andrew Hendley Fray , Winton Dennis Jones , Paul Leslie Ornstein , Richard Lee Simon , Hamideh Zarrinmayeh , Dennis Michael Zimmerman
IPC分类号： C07D23504
CPC分类号： C07D213/42 , C07C311/03 , C07C311/04 , C07D213/26 , C07D213/81 , C07D333/16 , C07D333/20
摘要： The present invention relates to the potentiation of glutamate receptor function using certain sulphonamide derivatives. It also relates to novel sulphonamide derivatives, to processes for their preparation and to pharmaceutical compositions containing them.
摘要翻译： 本发明涉及使用某些磺酰胺衍生物增强谷氨酸受体功能。 它还涉及新型磺酰胺衍生物，其制备方法和含有它们的药物组合物。
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公开(公告)号：US06713516B2
公开(公告)日：2004-03-30
申请号：US10318483
申请日：2002-12-12
申请人： Macklin Brian Arnold , David Michael Bender , Andrew Hendley Fray , Winton Dennis Jones , Paul Leslie Ornstein , Richard Lee Simon , Hamideh Zarrinmayeh , Dennis Michael Zimmerman
发明人： Macklin Brian Arnold , David Michael Bender , Andrew Hendley Fray , Winton Dennis Jones , Paul Leslie Ornstein , Richard Lee Simon , Hamideh Zarrinmayeh , Dennis Michael Zimmerman
IPC分类号： A61K3118
CPC分类号： C07D213/42 , C07C311/03 , C07C311/04 , C07D213/26 , C07D213/81 , C07D333/16 , C07D333/20
摘要： The present invention relates to the potentiation of glutamate receptor function using certain sulphonamide derivatives. It also relates to novel sulphonamide derivatives, to processes for their preparation and to pharmaceutical compositions containing them.
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