公开(公告)号：US08954019B2

公开(公告)日：2015-02-10

申请号：US13565955

申请日：2012-08-03

申请人： Liviu George ,  Simon Andrew Hughes ,  Christopher Robert Little ,  Tajinder Manku

发明人： Liviu George ,  Simon Andrew Hughes ,  Christopher Robert Little ,  Tajinder Manku

IPC分类号： H04B1/44

CPC分类号： H04B1/006 ,  H04B1/0057

摘要： A mobile wireless communications device may include an antenna, LTE RF differential inputs, and a front end circuit. The front end circuit may include band pass filters coupled to the antenna, LNAs coupled respectively to the band pass filters, and RF switching circuits. Each RF switching circuit may be respectively coupled between each LNA and a pair of LTE RF differential inputs and configured to switch to one or both of the pair of LTE RF differential inputs.

摘要翻译： 移动无线通信设备可以包括天线，LTE RF差分输入和前端电路。 前端电路可以包括耦合到天线的带通滤波器，分别耦合到带通滤波器的LNA和RF开关电路。 每个RF开关电路可以分别耦合在每个LNA和一对LTE RF差分输入之间，并且被配置为切换到一对LTE RF差分输入中的一个或两个。

公开(公告)号：US20140038663A1

公开(公告)日：2014-02-06

申请号：US13565904

申请日：2012-08-03

申请人： Liviu George ,  Christopher Robert Little ,  Simon Andrew Hughes

发明人： Liviu George ,  Christopher Robert Little ,  Simon Andrew Hughes

IPC分类号： H04W88/02

CPC分类号： H04B1/006

摘要： A mobile wireless communications device may include an antenna, primary RF receivers configured to operate at different RF bands, each primary RF receiver having a differential input, and secondary RF receivers also configured to operate at the different RF bands, each secondary RF receiver having a differential input. The mobile wireless communications device may also include first and second RF filters coupled to the antenna and configured to respectively pass first and second RF bands from among the different RF bands, and a first DDPDT RF switch coupled between the first and second RF filters and the differential inputs of respective first ones of the primary and secondary RF receivers.

摘要翻译： 移动无线通信设备可以包括天线，被配置为在不同RF频带操作的主RF接收机，每个主RF接收机具有差分输入，并且辅助RF接收机也被配置为在不同RF频带处操作，每个次RF接收机具有 差分输入 移动无线通信设备还可以包括耦合到天线的第一和第二RF滤波器，并且被配置为分别从不同RF频带中传送第一和第二RF频带，以及耦合在第一和第二RF滤波器之间的第一DDPDT RF开关和 主要和次要RF接收机中各自的第一个的差分输入。

公开(公告)号：US20140038532A1

公开(公告)日：2014-02-06

申请号：US13565955

申请日：2012-08-03

申请人： Liviu GEORGE ,  Simon Andrew Hughes ,  Christopher Robert Little ,  Tajinder Manku

发明人： Liviu GEORGE ,  Simon Andrew Hughes ,  Christopher Robert Little ,  Tajinder Manku

IPC分类号： H04B1/44 ,  H04W88/02

CPC分类号： H04B1/006 ,  H04B1/0057

摘要： A mobile wireless communications device may include an antenna, LTE RF differential inputs, and a front end circuit. The front end circuit may include band pass filters coupled to the antenna, LNAs coupled respectively to the band pass filters, and RF switching circuits. Each RF switching circuit may be respectively coupled between each LNA and a pair of LTE RF differential inputs and configured to switch to one or both of the pair of LTE RF differential inputs.

摘要翻译： 移动无线通信设备可以包括天线，LTE RF差分输入和前端电路。 前端电路可以包括耦合到天线的带通滤波器，分别耦合到带通滤波器的LNA和RF开关电路。 每个RF开关电路可以分别耦合在每个LNA和一对LTE RF差分输入之间，并且被配置为切换到一对LTE RF差分输入中的一个或两个。

公开(公告)号：US08475819B2

公开(公告)日：2013-07-02

申请号：US12971287

申请日：2010-12-17

申请人： Kenneth Andrew Hughes ,  George Philip Lahm ,  Thomas Paul Selby ,  Thomas Martin Stevenson

发明人： Kenneth Andrew Hughes ,  George Philip Lahm ,  Thomas Paul Selby ,  Thomas Martin Stevenson

IPC分类号： A01N25/02

CPC分类号： A01N43/56 ,  A01N43/16 ,  A01N43/24 ,  A01N43/54 ,  A01N43/707 ,  A01N43/84 ,  A01N43/88 ,  A01N57/14 ,  A01N57/28 ,  A01N59/02 ,  A01N59/20 ,  A01N63/00 ,  A01N63/02 ,  C07D401/04 ,  Y02A50/322 ,  Y02A50/326 ,  Y02A50/352 ,  Y02A50/356 ,  Y02A50/371 ,  Y02A50/373 ,  Y02A50/375

摘要： This invention provides compounds of Formula 1, N-oxides and suitable salts thereof wherein R1 is Me, Cl, Br or F; R2 is F, Cl, Br, C1-C4 haloalkyl or C1-C4 haloalkoxy; R3 is F, Cl or Br; R4 is H; C1-C4 alkyl, C3-C4 alkenyl, C3-C4 alkynyl, C3-C5 cycloalkyl, or C4-C6 cycloalkylalkyl, each optionally substituted with one substituent selected from the group consisting of halogen, CN, SMe, S(O)Me, S(O)2Me, and OMe; R5 is H or Me; R6 is H, F or Cl; and R7 is H, F or Cl. Also disclosed are methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound of Formula 1, an N-oxide thereof or a suitable salt of the compound (e.g., as a composition described herein). This invention also pertains to a composition for controlling an invertebrate pest comprising a biologically effective amount of a compound of Formula 1, an N-oxide thereof or a suitable salt of the compound and at least one additional component selected from the group consisting of a surfactant, a solid diluent and a liquid diluent.

公开(公告)号：US20110319452A1

公开(公告)日：2011-12-29

申请号：US12971287

申请日：2010-12-17

申请人： Kenneth Andrew Hughes ,  George Philip Lahm ,  Thomas Paul Selby ,  Thomas Martin Stevenson

发明人： Kenneth Andrew Hughes ,  George Philip Lahm ,  Thomas Paul Selby ,  Thomas Martin Stevenson

IPC分类号： A01N43/56 ,  A61P33/00 ,  A01P7/04 ,  A61K31/4439

CPC分类号： A01N43/56 ,  A01N43/16 ,  A01N43/24 ,  A01N43/54 ,  A01N43/707 ,  A01N43/84 ,  A01N43/88 ,  A01N57/14 ,  A01N57/28 ,  A01N59/02 ,  A01N59/20 ,  A01N63/00 ,  A01N63/02 ,  C07D401/04 ,  Y02A50/322 ,  Y02A50/326 ,  Y02A50/352 ,  Y02A50/356 ,  Y02A50/371 ,  Y02A50/373 ,  Y02A50/375

摘要： This invention provides compounds of Formula 1, N-oxides and suitable salts thereof wherein R1 is Me, Cl, Br or F; R2 is F, Cl, Br, C1-C4 haloalkyl or C1-C4 haloalkoxy; R3 is F, Cl or Br; R4 is H; C1-C4 alkyl, C3-C4 alkenyl, C3-C4 alkynyl, C3-C5 cycloalkyl, or C4-C6 cycloalkylalkyl, each optionally substituted with one substituent selected from the group consisting of halogen, CN, SMe, S(O)Me, S(O)2Me, and OMe; R5 is H or Me; R6 is H, F or Cl; and R7 is H, F or Cl. Also disclosed are methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound of Formula 1, an N-oxide thereof or a suitable salt of the compound (e.g., as a composition described herein). This invention also pertains to a composition for controlling an invertebrate pest comprising a biologically effective amount of a compound of Formula 1, an N-oxide thereof or a suitable salt of the compound and at least one additional component selected from the group consisting of a surfactant, a solid diluent and a liquid diluent.

摘要翻译： 本发明提供式1化合物，N-氧化物及其合适的盐，其中R 1是Me，Cl，Br或F; R2是F，Cl，Br，C1-C4卤代烷基或C1-C4卤代烷氧基; R3是F，Cl或Br; R4是H; C 1 -C 4烷基，C 3 -C 4烯基，C 3 -C 4炔基，C 3 -C 5环烷基或C 4 -C 6环烷基烷基，各自任选被一个选自卤素，CN，SMe，S（O） S（O）2e和OMe; R5是H或Me; R6是H，F或Cl; 且R7为H，F或Cl。 还公开了用于控制无脊椎害虫的方法，包括使无脊椎害虫或其环境与生物有效量的式1化合物，其N-氧化物或该化合物的合适盐（例如，如本文所述的组合物）接触， 。 本发明还涉及用于控制无脊椎害虫的组合物，其包含生物有效量的式1化合物，其N-氧化物或该化合物的合适盐，以及至少一种选自表面活性剂 ，固体稀释剂和液体稀释剂。

公开(公告)号：US20080142155A1

公开(公告)日：2008-06-19

申请号：US11923745

申请日：2007-10-25

申请人： Andrew Hughes ,  Morton Barrowmore Auld

发明人： Andrew Hughes ,  Morton Barrowmore Auld

IPC分类号： B32B38/04

CPC分类号： B07B1/4618 ,  B07B1/48 ,  Y10T156/108

摘要： In a method of and apparatus for manufacturing a filtering screen, a frame of plastics coated metal or reinforced plastics material is located in a jig and at least two sheets of wire cloths are placed over the frame and their edges gripped by pneumatically operated clamps carried by the jig. The clamps are pneumatically driven outwardly of the frame to tension each cloth in orthogonal directions. The tensioned cloths are pressed against the frame and heated in order to bond the cloths to the frame. The heated material is allowed to cool, and after completion of the bonding step the clamps a released, allowing the frame to be removed from the jig. Where necessary the cloths are trimmed back to the edges of the frame. A separate set of pneumatically operated clamps may be provided for gripping all four edges of each wire cloth layer to allow each layer to be individually tensioned.

摘要翻译： 在制造过滤网的方法和装置中，将塑料涂覆的金属或增强塑料材料的框架放置在夹具中，并且至少两层线材布置在框架上，并且其边缘由气动夹紧器 夹具 夹具被气动地从框架向外驱动以沿正交方向张紧每个布。 张紧的布被压靠在框架上并被加热以便将布料粘结到框架上。 允许加热的材料冷却，并且在结合步骤完成之后，夹具释放，允许框架从夹具上移除。 必要时将布修剪回到框架的边缘。 可以提供单独的一组气动夹具用于夹持每个线布层的所有四个边缘，以允许每个层单独张紧。

公开(公告)号：US20060122180A1

公开(公告)日：2006-06-08

申请号：US10530794

申请日：2003-10-07

申请人： Francis Boyle ,  Jon Curwen ,  Neil Gallagher ,  Ursula Hancox ,  Andrew Hughes ,  Donna Johnstone ,  Sian Taylor ,  David Tonge

发明人： Francis Boyle ,  Jon Curwen ,  Neil Gallagher ,  Ursula Hancox ,  Andrew Hughes ,  Donna Johnstone ,  Sian Taylor ,  David Tonge

IPC分类号： A61K31/5377 ,  A61K31/517 ,  A61K31/4965 ,  A61K31/497 ,  A61K31/422 ,  A61K31/42

CPC分类号： A61K45/06 ,  A61K31/517 ,  A61K2300/00

摘要： A combination, comprising an endothelin receptor antagonist, or a pharmaceutically acceptable salt thereof, and an EGFR TKI, or a pharmaceutically acceptable salt thereof is described.

摘要翻译： 描述了包含内皮素受体拮抗剂或其药学上可接受的盐和EGFR TKI或其药学上可接受的盐的组合。

公开(公告)号：US20060094729A1

公开(公告)日：2006-05-04

申请号：US10524963

申请日：2003-08-20

申请人： David Tonge ,  Sian Tayer ,  Francis Boyle ,  Andrew Hughes ,  Donna Johnstone ,  Marianne Ashford ,  Nigel Barrass

发明人： David Tonge ,  Sian Tayer ,  Francis Boyle ,  Andrew Hughes ,  Donna Johnstone ,  Marianne Ashford ,  Nigel Barrass

IPC分类号： A61K31/497

CPC分类号： A61K31/497

摘要： The use of N-(3-methoxy-5-methylpyrazin-2-yl)-2-(4-[1,3,4-oxadiazol-2-yl]phenyl)pyridine-3-sulphonamide, or a pharmaceutically acceptable salt thereof, in the treatment of cancer and/or pain in a warm blooded animal such as man is described.

摘要翻译： 使用N-（3-甲氧基-5-甲基吡嗪-2-基）-2-（4- [1,3,4-恶二唑-2-基]苯基）吡啶-3-磺酰胺或其药学上可接受的盐 描述了在诸如人类的温血动物中治疗癌症和/或疼痛。

公开(公告)号：US06800163B2

公开(公告)日：2004-10-05

申请号：US10097900

申请日：2002-03-13

申请人： Gordon James Cook ,  Andrew Hughes ,  Arthur Robert Bailey ,  George Charles Hartnup ,  Dugald Stewart

发明人： Gordon James Cook ,  Andrew Hughes ,  Arthur Robert Bailey ,  George Charles Hartnup ,  Dugald Stewart

IPC分类号： B32B3116

CPC分类号： B07B1/4618 ,  B01D29/012 ,  B01D29/05 ,  B01D29/445 ,  B07B1/46 ,  B07B1/4627 ,  B07B1/4645 ,  B07B1/4663 ,  B07B1/4672 ,  B07B1/48 ,  B29C45/14336 ,  B29C70/56 ,  B29C70/82 ,  B29C70/885 ,  B29C2045/14442 ,  B29L2031/14 ,  B29L2031/737 ,  Y10T29/49616 ,  Y10T29/4962 ,  Y10T29/49895 ,  Y10T428/12347 ,  Y10T428/12361 ,  Y10T428/12444 ,  Y10T428/12965 ,  Y10T428/249923 ,  Y10T428/298

摘要： A method of constructing a filter screen is described. This involves forming a polymer support frame including therein a plurality of substantially similarly sized rectilinear apertures, defined by an integral rectilinear matrix of wire reinforced struts of polymer material. An upper edge of each strut is ridged and an upper surface of each boundary of the support frame provided with a plurality of ridges. One or more woven wirecloths are fitted over the ridges and tensioned. The wirecloths are secured in place by heating at least the ridges so as to soften the polymer material sufficiently to allow the wirecloths to penetrate crests of the ridges and upon cooling to remain embedded therein. This maintains tension in the wirecloths after cooling. The wires in one of the wirecloths are preferably tensioned differently from those in the other, so that different tensions exist in the wires of the two cloths after bonding to the frame.

摘要翻译： 描述了构造过滤器屏幕的方法。 这包括形成聚合物支撑框架，其中包括由聚合物材料的钢丝增强支柱的整体直线基质限定的多个基本相似尺寸的直线孔。 每个支柱的上边缘是脊状的，并且支撑框架的每个边界的上表面设置有多个脊。 一根或多根编织布线安装在脊上并张紧。 通过加热至少脊部将布线固定在适当的位置，以充分软化聚合物材料，以允许布线穿过脊的波峰并在冷却时保持嵌入其中。 这样可以在冷却后保持钢丝网的张力。 其中一根丝线中的线优选地与另一条线中的线不同地拉紧，使得在结合到框架之后两根布的线中存在不同的张力。

公开(公告)号：US06759000B2

公开(公告)日：2004-07-06

申请号：US10025070

申请日：2001-12-19

申请人： Gordon James Cook ,  Andrew Hughes ,  Arthur Robert Bailey ,  George Charles Hartnup ,  Dugald Stewart

发明人： Gordon James Cook ,  Andrew Hughes ,  Arthur Robert Bailey ,  George Charles Hartnup ,  Dugald Stewart

IPC分类号： B29C4514

CPC分类号： B07B1/4618 ,  B01D29/012 ,  B01D29/05 ,  B01D29/445 ,  B07B1/46 ,  B07B1/4627 ,  B07B1/4645 ,  B07B1/4663 ,  B07B1/4672 ,  B07B1/48 ,  B29C45/14336 ,  B29C70/56 ,  B29C70/82 ,  B29C70/885 ,  B29C2045/14442 ,  B29L2031/14 ,  B29L2031/737 ,  Y10T29/49616 ,  Y10T29/4962 ,  Y10T29/49895 ,  Y10T428/12347 ,  Y10T428/12361 ,  Y10T428/12444 ,  Y10T428/12965 ,  Y10T428/249923 ,  Y10T428/298

摘要： A method of constructing a frame (10) for a filtering screen from a polymer material is described in which a wire frame reinforcement is wholly encapsulated during the frame moulding process so that two parallel spaced apart wires extend through each of the intersecting orthogonal ribs (14, 16) which define the open area of the frame (10) across which the wirecloths (158, 159) are stretched. The surfaces of the frame (10) in which the wirecloths (158, 159) are embedded are formed with ridges (22, 30, 32) and the crests of the latter extend to different heights. The crests are softened by heating during the manufacturing process and the wirecloths (158, 159) stretched over the frame (10) are forced into the softened crests after which the assembly is allowed to cool and cure. The frame (10) is re-usable by stripping wirecloths (158, 159) from the top of the frame (10) and fitting fresh wirecloths over the plastics material and heating the regions which are to encapsulate the fresh wirecloth.

摘要翻译： 描述了从聚合物材料构造用于过滤筛网的框架（10）的方法，其中线框架加强件在框架模制过程中被完全封装，使得两个平行间隔开的​​线材延伸通过每个相交的正交肋（14） ，16），其限定所述框架（10）的开放区域，所述布线（158,159）被拉伸。 其中嵌入有布线（158,159）的框架（10）的表面形成有脊（22,30,32），并且后者的顶部延伸到不同的高度。 在制造过程中，通过加热使波峰软化，并且在框架（10）上拉伸的布线（158,159）被迫进入软化的波峰中，在此之后允许组件冷却和固化。 框架（10）可以通过从框架（10）的顶部剥离钢丝绳（158,159）来重新使用，并且将新鲜的布线装配在塑料材料上并加热要封装新的布线的区域。