公开(公告)号：US07645771B2

公开(公告)日：2010-01-12

申请号：US10538144

申请日：2003-12-12

申请人： Wieslaw Mieczyslaw Kazmierski ,  Chrisopher Joseph Aquino ,  Neil Bifulco ,  Eric Eugene Boros ,  Brian Andrew Chauder ,  Pek Yoke Chong ,  Maosheng Duan ,  Felix Deanda, Jr. ,  Cecilia Suarez Koble ,  Ed Williams McLean ,  Jennifer Poole Peckham ,  Angilique C Perkins ,  James Benjamin Thompson ,  Dana Vanderwall

发明人： Wieslaw Mieczyslaw Kazmierski ,  Chrisopher Joseph Aquino ,  Neil Bifulco ,  Eric Eugene Boros ,  Brian Andrew Chauder ,  Pek Yoke Chong ,  Maosheng Duan ,  Felix Deanda, Jr. ,  Cecilia Suarez Koble ,  Ed Williams McLean ,  Jennifer Poole Peckham ,  Angilique C Perkins ,  James Benjamin Thompson ,  Dana Vanderwall

IPC分类号： A61K31/46

CPC分类号： C07D451/04

摘要： The present invention relates to compounds of formula (I) or a pharmaceutically acceptable derivatives thereof, useful in the treatment of prophylazis of CCR5-related diseases and disorders, for example, in the inhibition of HIV replication, the prevention or treatment of HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).

摘要翻译： 本发明涉及式（I）化合物或其药学上可接受的衍生物，其可用于治疗CCR5相关疾病和病症的预防，例如抑制HIV复制，预防或治疗HIV感染， 以及治疗所得的获得性免疫缺陷综合征（AIDS）。