摘要:
The present invention relates to methods of inhibiting native and promiscuous uptake of biogenic amine neurotransmitters with triple reuptake inhibitors in the treatment of conditions affected by monoamine neurotransmitters.
摘要:
In one embodiment a layered pharmaceutical formulation includes two or more pharmaceutical layers and an intermediate layer disposed between at least two of the two or more pharmaceutical layers, the intermediate layer configured to dissolve in vivo to thereby leave the two or more pharmaceutical layers substantially intact. In one embodiment, an active pharmaceutical ingredient in at least one of the pharmaceutical layers is selected from bupropion, zonisamide, naltrexone, topiramate, phentermine, metformin, olanzapine and fluoxetine.
摘要:
In one embodiment a layered pharmaceutical formulation includes two or more pharmaceutical layers and an intermediate layer disposed between at least two of the two or more pharmaceutical layers, the intermediate layer configured to dissolve in vivo to thereby leave the two or more pharmaceutical layers substantially intact. In one embodiment, an active pharmaceutical ingredient in at least one of the pharmaceutical layers is selected from bupropion, zonisamide, naltrexone, topiramate, phentermine, metformin, olanzapine and fluoxetine.
摘要:
Methods and systems for administration of pharmaceuticals using a unit dosage package that includes a first unit dosage that has a first drug and a second drug, a second unit dosage that has the first drug and the second drug, where the second unit dosage includes a different amount of the second drug than the first unit dosage and a unit dosage package is configured to hold the first unit dosage and the second unit dosage. In preferred embodiments the methods and systems are used for administration of weight loss medications.
摘要:
Pharmaceutical formulations comprise sustained-release zonisamide. Methods of preparing such pharmaceutical formulations involve intermixing zonisamide with a suitable excipient configured to control the dissolution profile of the zonisamide. Methods of treatment involve administering the pharmaceutical formulations to patients in need of such treatment.
摘要:
Disclosed are compositions for reducing food cravings, comprising a first compound and a second compound, where the first compound is an opioid antagonist and the second compound is an α-MSH agonist. Also disclosed are methods of reducing food cravings, comprising identifying an individual in need thereof and treating that individual to antagonize opioid receptor activity and to enhance α-MSH activity.
摘要:
The vitality of a swimmer, or of a child, is monitored by a periodically-activated micro-powered solar- and battery-powered waterproof microminiaturized (1) optical sensor of heart activity, electrically connected to (2) a microprocessor monitor, for jointly determining when a person's heart activity has stopped. When and if required, the microprocessor causes to be transmitted, through water a blue-green light alarm signal. When this optical alarm signal is received by an optical receiver/alarm in air, the receiver/alarm produces an audio and/or visual alarm that, when sensed by a human, potentially timely permits rescue and resuscitation of the swimmer, or the child. The battery-and-solar-powered monitor that forms the core of the vitality monitoring system is roughly ten times faster and more capable, with but one-tenth the power consumption, than previous real-time biological monitoring systems.
摘要:
A band, or bracelet, is semi-permanently attachable to, and wearable about, a limb of the human body. The limb band is in the physical form of a familiar, and well-accepted, flexible plastic hospital-type wrist bracelet. As well as providing a physical platform to attach, and to mount, any of a large number of diverse portable electronic physiological, motion and like sensors of the human body and its condition, the limb band houses, and electrically connects, any of (1) a battery that is preferably rechargeable, (2) a solar cell for recharging the battery, (3) an antenna, and/or (4) a universal electronic signal connector (such as a miniature USB connector port). In this manner the limb band economically serves as a universal platform for mounting, supplying power and/or abetting wireless and wired communication to and from, wearable electronic sensors and monitors of humans and animals.
摘要:
In one embodiment a layered pharmaceutical formulation includes two or more pharmaceutical layers and an intermediate layer disposed between at least two of the two or more pharmaceutical layers, the intermediate layer configured to dissolve in vivo to thereby leave the two or more pharmaceutical layers substantially intact. In one embodiment, an active pharmaceutical ingredient in at least one of the pharmaceutical layers is selected from bupropion, zonisamide, naltrexone, topiramate, phentermine, metformin, olanzapine and fluoxetine.
摘要:
In one embodiment a layered pharmaceutical formulation includes two or more pharmaceutical layers and an intermediate layer disposed between at least two of the two or more pharmaceutical layers, the intermediate layer configured to dissolve in vivo to thereby leave the two or more pharmaceutical layers substantially intact. In one embodiment, an active pharmaceutical ingredient in at least one of the pharmaceutical layers is selected from bupropion, zonisamide, naltrexone, topiramate, phentermine, metformin, olanzapine and fluoxetine.