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Patent Agency Ranking
公开(公告)号：US20080160019A1
公开(公告)日：2008-07-03
申请号：US11873856
申请日：2007-10-17
Applicant: Clive R. Wood , Daniel T. Dransfield , Antonio Arulanandam , Rakesh K. Jain
Inventor： Clive R. Wood , Daniel T. Dransfield , Antonio Arulanandam , Rakesh K. Jain
IPC: A61K39/395 , A61K31/44 , A61P35/00
CPC classification number: A61K45/06 , A61K39/3955 , A61K2300/00
Abstract: Disclosed are new methods for treatment of angiogenesis-related disorders. Angiogenesis-related disorders are treated by administration of a Tie1 ectodomain-binding agent and a VEGF antagonist agent.
Abstract translation: 公开了治疗血管生成相关疾病的新方法。 通过施用Tie1胞外域结合剂和VEGF拮抗剂来治疗血管发生相关病症。
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公开(公告)号：US20050054706A1
公开(公告)日：2005-03-10
申请号：US10491902
申请日：2002-10-23
Applicant: Stephen Arkinstall , Antonio Arulanandam , Xuliang Jiang , Sharad Magar , Roustem Nabioullin , John Zhang , Peter Blume-Jensen
Inventor： Stephen Arkinstall , Antonio Arulanandam , Xuliang Jiang , Sharad Magar , Roustem Nabioullin , John Zhang , Peter Blume-Jensen
IPC: A61K31/41 , A61K31/4164 , A61K31/417 , A61K31/4178 , A61K31/4196 , A61K31/4439 , A61P1/04 , A61P1/14 , A61P1/18 , A61P3/10 , A61P5/14 , A61P7/00 , A61P7/02 , A61P7/06 , A61P7/10 , A61P9/00 , A61P9/14 , A61P11/00 , A61P11/06 , A61P13/12 , A61P15/06 , A61P15/08 , A61P15/10 , A61P17/00 , A61P17/02 , A61P19/00 , A61P19/02 , A61P19/10 , A61P25/04 , A61P25/28 , A61P27/02 , A61P29/00 , A61P31/00 , A61P31/04 , A61P31/18 , A61P35/00 , A61P35/02 , A61P35/04 , A61P37/00 , A61P37/02 , A61P37/08 , A61P43/00 , C07D233/54 , C07D233/60 , C07D233/61 , C07D233/68 , C07D249/08 , C07D257/04 , C07D401/12 , C07D405/12 , A61K31/415 , A61K31/416
CPC classification number: C07D233/60 , A61K31/41 , A61K31/4164 , A61K31/4178 , A61K31/4439 , C07D233/54 , C07D233/56 , C07D233/61 , C07D233/64 , C07D233/68 , C07D249/08 , C07D257/04 , C07D401/12 , C07D405/12
Abstract: The invention provides substituted pyrazolidinone compounds, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are useful for a variety of therapies, including treating or preventing various cancers, inflammation, septic shock, preterm labor, infertility, pain, and ischemia, and other diseases and disorders associated with MEK-1 and/or ERK-2 activation.
Abstract translation: 本发明提供取代的吡唑烷酮化合物，以及使用或包含一种或多种这些化合物的治疗方法和药物组合物。 本发明的化合物可用于各种疗法，包括治疗或预防各种癌症，炎症，败血性休克，早产，不孕，疼痛和缺血以及与MEK-1和/或ERK-2相关的其它疾病和病症 激活。
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公开(公告)号：US20070293555A1
公开(公告)日：2007-12-20
申请号：US11782251
申请日：2007-07-24
Applicant: Stephen ARKINSTALL , Antonio Arulanandam , Xuliang Jiang , Sharad Magar , Roustem Nabioullin , John Zhang , Peter Blume-Jensen
Inventor： Stephen ARKINSTALL , Antonio Arulanandam , Xuliang Jiang , Sharad Magar , Roustem Nabioullin , John Zhang , Peter Blume-Jensen
IPC: A61K31/4196 , A61K31/417 , A61P15/08 , A61P29/00 , A61P31/00 , A61P35/00 , A61P9/10
CPC classification number: C07D233/60 , A61K31/41 , A61K31/4164 , A61K31/4178 , A61K31/4439 , C07D233/54 , C07D233/56 , C07D233/61 , C07D233/64 , C07D233/68 , C07D249/08 , C07D257/04 , C07D401/12 , C07D405/12
Abstract: The invention provides substituted pyrazolidinone compounds, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are useful for a variety of therapies, including treating or preventing various cancers, inflammation, septic shock, preterm labor, infertility, pain, and ischemia, and other diseases and disorders associated with MEK-1 and/or ERK-2 activation.
Abstract translation: 本发明提供取代的吡唑烷酮化合物，以及使用或包含一种或多种这些化合物的治疗方法和药物组合物。 本发明的化合物可用于各种疗法，包括治疗或预防各种癌症，炎症，败血性休克，早产，不孕，疼痛和缺血以及与MEK-1和/或ERK-2相关的其它疾病和病症 激活。
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公开(公告)号：US07541375B2
公开(公告)日：2009-06-02
申请号：US11782251
申请日：2007-07-24
Applicant: Stephen J. Arkinstall , Antonio Arulanandam , Xuliang Jiang , Sharad Magar , Roustem Nabioullin , John Yingsheng Zhang , Peter Blume-Jensen
Inventor： Stephen J. Arkinstall , Antonio Arulanandam , Xuliang Jiang , Sharad Magar , Roustem Nabioullin , John Yingsheng Zhang , Peter Blume-Jensen
IPC: A61K31/415 , C07D233/00
CPC classification number: C07D233/60 , A61K31/41 , A61K31/4164 , A61K31/4178 , A61K31/4439 , C07D233/54 , C07D233/56 , C07D233/61 , C07D233/64 , C07D233/68 , C07D249/08 , C07D257/04 , C07D401/12 , C07D405/12
Abstract: The invention provides substituted pyrazolidinone compounds, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are useful for a variety of therapies, including treating or preventing various cancers, inflammation, septic shock, preterm labor, infertility, pain, and ischemia, and other diseases and disorders associated with MEK-1 and/or ERK-2 activation.
Abstract translation: 本发明提供取代的吡唑烷酮化合物，以及使用或包含一种或多种这些化合物的治疗方法和药物组合物。 本发明的化合物可用于各种疗法，包括治疗或预防各种癌症，炎症，败血性休克，早产，不孕，疼痛和缺血以及与MEK-1和/或ERK-2相关的其它疾病和病症 激活。
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公开(公告)号：US07253199B2
公开(公告)日：2007-08-07
申请号：US10491902
申请日：2002-10-23
Applicant: Stephen J. Arkinstall , Antonio Arulanandam , Xuliang Jiang , Sharad Magar , Roustem Nabioullin , John Yingsheng Zhang , Peter Blume-Jensen
Inventor： Stephen J. Arkinstall , Antonio Arulanandam , Xuliang Jiang , Sharad Magar , Roustem Nabioullin , John Yingsheng Zhang , Peter Blume-Jensen
IPC: A61K31/415 , C07D233/00
CPC classification number: C07D233/60 , A61K31/41 , A61K31/4164 , A61K31/4178 , A61K31/4439 , C07D233/54 , C07D233/56 , C07D233/61 , C07D233/64 , C07D233/68 , C07D249/08 , C07D257/04 , C07D401/12 , C07D405/12
Abstract: The invention provides substituted pyrazolidinone compounds, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are useful for a variety of therapies, including treating or preventing various cancers, inflammation, septic shock, preterm labor, infertility, pain, and ischemia, and other diseases and disorders associated with MEK-1 and/or ERK-2 activation.
Abstract translation: 本发明提供取代的吡唑烷酮化合物，以及使用或包含一种或多种这些化合物的治疗方法和药物组合物。 本发明的化合物可用于各种疗法，包括治疗或预防各种癌症，炎症，败血性休克，早产，不孕，疼痛和缺血以及与MEK-1和/或ERK-2相关的其它疾病和病症 激活。
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