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1.
公开(公告)号:US08895321B2
公开(公告)日:2014-11-25
申请号:US13104200
申请日:2011-05-10
IPC分类号: G01N33/537 , G01N27/447
CPC分类号: G01N27/44721 , G01N33/5304 , G01N33/54366 , Y10S977/92
摘要: Device and method for detecting the presence of known or unknown toxic agents in a fluid sample. Targets in the sample are bound to releasable receptors immobilized in a reaction region of a micro- or nano-fluidic device. The receptors are selected based on their affinity for classes of known toxic agents. The receptors are freed and the bound and unbound receptors separated based on differential electrokinetic mobilities while they travel to a detection device.
摘要翻译: 用于检测流体样品中已知或未知毒物的存在的装置和方法。 样品中的靶标与固定在微流体或纳米流体装置的反应区域中的可释放受体结合。 基于它们对已知毒性剂类的亲和性来选择受体。 受体被释放,并且结合和未结合的受体在移动到检测装置的同时基于差异电动迁移率分离。
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2.
公开(公告)号:US20140110258A1
公开(公告)日:2014-04-24
申请号:US13104200
申请日:2011-05-10
IPC分类号: G01N27/447
CPC分类号: G01N27/44721 , G01N33/5304 , G01N33/54366 , Y10S977/92
摘要: Device and method for detecting the presence of known or unknown toxic agents in a fluid sample. Targets in the sample are bound to releasable receptors immobilized in a reaction region of a micro- or nano-fluidic device. The receptors are selected based on their affinity for classes of known toxic agents. The receptors are freed and the bound and unbound receptors separated based on differential electrokinetic mobilities while they travel to a detection device.
摘要翻译: 用于检测流体样品中已知或未知毒物的存在的装置和方法。 样品中的靶标与固定在微流体或纳米流体装置的反应区域中的可释放受体结合。 基于它们对已知毒性剂类的亲和性来选择受体。 受体被释放,并且结合和未结合的受体在移动到检测装置的同时基于差异电动迁移率分离。
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3.
公开(公告)号:US07959861B2
公开(公告)日:2011-06-14
申请号:US12102663
申请日:2008-04-14
CPC分类号: G01N27/44721 , G01N33/5304 , G01N33/54366 , Y10S977/92
摘要: Device and method for detecting the presence of known or unknown toxic agents in a fluid sample. Targets in the sample are bound to releasable receptors immobilized in a reaction region of a micro- or nano-fluidic device. The receptors are selected based on their affinity for classes of known toxic agents. The receptors are freed and the bound and unbound receptors separated based on differential electrokinetic mobilities while they travel to a detection device.
摘要翻译: 用于检测流体样品中已知或未知毒物的存在的装置和方法。 样品中的靶标与固定在微流体或纳米流体装置的反应区域中的可释放受体结合。 基于它们对已知毒性剂类的亲和性来选择受体。 受体被释放,并且结合和未结合的受体在移动到检测装置的同时基于差异电动迁移率分离。
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4.
公开(公告)号:US20090075393A1
公开(公告)日:2009-03-19
申请号:US12102663
申请日:2008-04-14
CPC分类号: G01N27/44721 , G01N33/5304 , G01N33/54366 , Y10S977/92
摘要: Device and method for detecting the presence of known or unknown toxic agents in a fluid sample. Targets in the sample are bound to releasable receptors immobilized in a reaction region of a micro- or nano-fluidic device. The receptors are selected based on their affinity for classes of known toxic agents. The receptors are freed and the bound and unbound receptors separated based on differential electrokinetic mobilities while they travel to a detection device.
摘要翻译: 用于检测流体样品中已知或未知毒物的存在的装置和方法。 样品中的靶标与固定在微流体或纳米流体装置的反应区域中的可释放受体结合。 基于它们对已知毒性剂类的亲和性来选择受体。 受体被释放,并且结合和未结合的受体在移动到检测装置的同时基于差异电动迁移率分离。
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