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公开(公告)号：US07959861B2
公开(公告)日：2011-06-14
申请号：US12102663
申请日：2008-04-14
CPC分类号： G01N27/44721 , G01N33/5304 , G01N33/54366 , Y10S977/92
摘要： Device and method for detecting the presence of known or unknown toxic agents in a fluid sample. Targets in the sample are bound to releasable receptors immobilized in a reaction region of a micro- or nano-fluidic device. The receptors are selected based on their affinity for classes of known toxic agents. The receptors are freed and the bound and unbound receptors separated based on differential electrokinetic mobilities while they travel to a detection device.
摘要翻译： 用于检测流体样品中已知或未知毒物的存在的装置和方法。 样品中的靶标与固定在微流体或纳米流体装置的反应区域中的可释放受体结合。 基于它们对已知毒性剂类的亲和性来选择受体。 受体被释放，并且结合和未结合的受体在移动到检测装置的同时基于差异电动迁移率分离。
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公开(公告)号：US08895321B2
公开(公告)日：2014-11-25
申请号：US13104200
申请日：2011-05-10
IPC分类号： G01N33/537 , G01N27/447
CPC分类号： G01N27/44721 , G01N33/5304 , G01N33/54366 , Y10S977/92
摘要： Device and method for detecting the presence of known or unknown toxic agents in a fluid sample. Targets in the sample are bound to releasable receptors immobilized in a reaction region of a micro- or nano-fluidic device. The receptors are selected based on their affinity for classes of known toxic agents. The receptors are freed and the bound and unbound receptors separated based on differential electrokinetic mobilities while they travel to a detection device.
摘要翻译： 用于检测流体样品中已知或未知毒物的存在的装置和方法。 样品中的靶标与固定在微流体或纳米流体装置的反应区域中的可释放受体结合。 基于它们对已知毒性剂类的亲和性来选择受体。 受体被释放，并且结合和未结合的受体在移动到检测装置的同时基于差异电动迁移率分离。
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3.发明申请公开(公告)号：US20140110258A1
公开(公告)日：2014-04-24
申请号：US13104200
申请日：2011-05-10
IPC分类号： G01N27/447
CPC分类号： G01N27/44721 , G01N33/5304 , G01N33/54366 , Y10S977/92
摘要： Device and method for detecting the presence of known or unknown toxic agents in a fluid sample. Targets in the sample are bound to releasable receptors immobilized in a reaction region of a micro- or nano-fluidic device. The receptors are selected based on their affinity for classes of known toxic agents. The receptors are freed and the bound and unbound receptors separated based on differential electrokinetic mobilities while they travel to a detection device.
摘要翻译： 用于检测流体样品中已知或未知毒物的存在的装置和方法。 样品中的靶标与固定在微流体或纳米流体装置的反应区域中的可释放受体结合。 基于它们对已知毒性剂类的亲和性来选择受体。 受体被释放，并且结合和未结合的受体在移动到检测装置的同时基于差异电动迁移率分离。
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公开(公告)号：US20090075393A1
公开(公告)日：2009-03-19
申请号：US12102663
申请日：2008-04-14
CPC分类号： G01N27/44721 , G01N33/5304 , G01N33/54366 , Y10S977/92
摘要： Device and method for detecting the presence of known or unknown toxic agents in a fluid sample. Targets in the sample are bound to releasable receptors immobilized in a reaction region of a micro- or nano-fluidic device. The receptors are selected based on their affinity for classes of known toxic agents. The receptors are freed and the bound and unbound receptors separated based on differential electrokinetic mobilities while they travel to a detection device.
摘要翻译： 用于检测流体样品中已知或未知毒物的存在的装置和方法。 样品中的靶标与固定在微流体或纳米流体装置的反应区域中的可释放受体结合。 基于它们对已知毒性剂类的亲和性来选择受体。 受体被释放，并且结合和未结合的受体在移动到检测装置的同时基于差异电动迁移率分离。
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5.发明授权Method for multivariate analysis of confocal temporal image sequences for velocity estimation 有权用于速度估计的共焦时间图像序列的多变量分析方法公开(公告)号：US08045140B2
公开(公告)日：2011-10-25
申请号：US12288447
申请日：2008-10-20
IPC分类号： G01P3/36
CPC分类号： G06T7/20 , G06T2207/10056 , G06T2207/30004
摘要： A method of determining individual velocity associated with one or more molecular species moving through a fluid medium involves obtaining multiple temporal images of the one or more species moving through the medium, analyzing the temporal images using multivariate image analysis to obtain temporal profiles of principal components, and determining individual velocity of the one or more species using the temporal profiles. Multiple species can be identified using the one or more individual velocities or ratio thereof.
摘要翻译： 确定与通过流体介质移动的一种或多种分子种类相关联的个体速度的方法涉及获得移动通过介质的一种或多种物质的多个时间图像，使用多变量图像分析分析时间图像以获得主成分的时间分布， 以及使用所述时间分布来确定所述一个或多个物种的个体速度。 可以使用一个或多个单独的速度或其比例来鉴定多个物种。
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6.发明申请Method for multivariate analysis of confocal temporal image sequences for velocity estimation 有权用于速度估计的共焦时间图像序列的多变量分析方法公开(公告)号：US20090148001A1
公开(公告)日：2009-06-11
申请号：US12288447
申请日：2008-10-20
IPC分类号： G06K9/00
CPC分类号： G06T7/20 , G06T2207/10056 , G06T2207/30004
摘要： A method of determining individual velocity associated with one or more molecular species moving through a fluid medium involves obtaining multiple temporal images of the one or more species moving through the medium, analyzing the temporal images using multivariate image analysis to obtain temporal profiles of principal components, and determining individual velocity of the one or more species using the temporal profiles. Multiple species can be identified using the one or more individual velocities or ratio thereof.
摘要翻译： 确定与通过流体介质移动的一种或多种分子种类相关联的个体速度的方法涉及获得移动通过介质的一种或多种物质的多个时间图像，使用多变量图像分析分析时间图像以获得主成分的时间分布， 以及使用所述时间分布来确定所述一个或多个物种的个体速度。 可以使用一个或多个单独的速度或其比例来鉴定多个物种。
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公开(公告)号：US09623393B2
公开(公告)日：2017-04-18
申请号：US12610322
申请日：2009-11-01
IPC分类号： B01J19/00 , C01B3/22 , B01J12/00 , B01J19/24 , B01J23/42 , B01J23/44 , B01J23/46 , B01J23/50 , B01J23/52 , B01J37/02 , B01J21/04 , B01J21/06 , B01J21/08 , B01J21/18
CPC分类号： B01J12/007 , B01J19/2485 , B01J21/04 , B01J21/063 , B01J21/08 , B01J21/18 , B01J23/42 , B01J23/44 , B01J23/464 , B01J23/50 , B01J23/52 , B01J37/0201 , B01J2219/00006 , B01J2219/00063 , B01J2219/00094 , B01J2219/00117 , B01J2219/00155 , C01B3/22 , C01B2203/0277 , C01B2203/04 , C01B2203/048 , C01B2203/1023 , C01B2203/1041 , C01B2203/1064 , C01B2203/107 , C01B2203/1082 , C01B2203/1217 , C01B2203/1288 , C01B2203/148 , C01B2203/1619 , C01B2203/1623 , C01B2203/169
摘要： There is disclosed a surprising reaction of an alkane thiol with a catalyst and heat to become dehydrogenated and form a thiophene rather than an expected desulfurization reaction to form the corresponding alkane or alkene. Moreover, there are disclosed surprising results regarding the form of a catalyst to allow a reaction of an alkane thiol to form the dehydrogenated thiophene at lower temperatures and at higher conversion percentages to allow for more efficient recovery of thiophenes to allow for recycling and reuse of thiophenes to hydrogenate to form alkane thiols. Further still, there is disclosed a set of reaction conditions and catalyst presentation that allows for recovery of usable diatomic hydrogen gas from a dehydrogenation reaction of substituted or unsubstituted cyclic thioethers to substituted or unsubstituted thiophene.
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公开(公告)号：US20110020214A1
公开(公告)日：2011-01-27
申请号：US12610322
申请日：2009-11-01
CPC分类号： B01J12/007 , B01J19/2485 , B01J21/04 , B01J21/063 , B01J21/08 , B01J21/18 , B01J23/42 , B01J23/44 , B01J23/464 , B01J23/50 , B01J23/52 , B01J37/0201 , B01J2219/00006 , B01J2219/00063 , B01J2219/00094 , B01J2219/00117 , B01J2219/00155 , C01B3/22 , C01B2203/0277 , C01B2203/04 , C01B2203/048 , C01B2203/1023 , C01B2203/1041 , C01B2203/1064 , C01B2203/107 , C01B2203/1082 , C01B2203/1217 , C01B2203/1288 , C01B2203/148 , C01B2203/1619 , C01B2203/1623 , C01B2203/169
摘要： There is disclosed a surprising reaction of an alkane thiol with a catalyst and heat to become dehydrogenated and form a thiophene rather than an expected desulfurization reaction to form the corresponding alkane or alkene. Moreover, there are disclosed surprising results regarding the form of a catalyst to allow a reaction of an alkane thiol to form the dehydrogenated thiophene at lower temperatures and at higher conversion percentages to allow for more efficient recovery of thiophenes to allow for recycling and reuse of thiophenes to hydrogenate to form alkane thiols. Further still, there is disclosed a set of reaction conditions and catalyst presentation that allows for recovery of usable diatomic hydrogen gas from a dehydrogenation reaction of substituted or unsubstituted cyclic thioethers to substituted or unsubstituted thiophene.
摘要翻译： 公开了烷烃硫醇与催化剂和热量的惊人反应，使其脱氢并形成噻吩，而不是预期的脱硫反应以形成相应的烷烃或烯烃。 此外，已经公开了关于催化剂形式的令人惊奇的结果，该催化剂允许烷烃硫醇在较低温度下反应形成脱氢噻吩并且以较高的转化百分数进行反应，以允许更有效地回收噻吩以允许噻吩的再循环和再利用 氢化形成烷硫醇。 此外，还公开了一组反应条件和催化剂表现，其允许从取代或未取代的环状硫醚脱氢反应到取代或未取代的噻吩中回收可用的双原子氢气。
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