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公开(公告)号:US06548302B1
公开(公告)日:2003-04-15
申请号:US09336390
申请日:1999-06-18
IPC分类号: A61K4800
CPC分类号: C08J9/00 , A61K9/1641 , A61K9/1647 , A61K48/00 , A61K2039/55555 , C08J2399/00 , C12N15/88 , Y10S977/906
摘要: The present invention relates to compositions and methods for delivery of nucleic acids. In particular, the invention provides a polymeric delivery formulation including a nucleic acid to be transfected into a host cell, formulated in a biodegradable polymer having phosphorous-based linkages.
摘要翻译: 本发明涉及递送核酸的组合物和方法。 特别地,本发明提供了一种包含待转染宿主细胞的核酸的聚合递送制剂,其配制在具有磷基连接的可生物降解的聚合物中。