-
公开(公告)号：US09308183B2
公开(公告)日：2016-04-12
申请号：US12306953
申请日：2007-06-29
申请人： Cara Heers , Thomas Stoehr , Bettina Beyreuther
发明人： Cara Heers , Thomas Stoehr , Bettina Beyreuther
IPC分类号： A61K31/165 , G01N33/68 , A61K31/19 , A61K31/195 , A61K31/35 , A61K31/4015 , A61K31/4166 , A61K31/53 , A61K31/55 , A61K38/04 , A61K38/05 , A61K45/06
CPC分类号： A61K31/165 , A61K31/19 , A61K31/195 , A61K31/35 , A61K31/4015 , A61K31/4166 , A61K31/53 , A61K31/55 , A61K38/04 , A61K38/05 , A61K45/06 , C12N2503/02 , G01N33/6896 , G01N2500/04 , G01N2800/2835 , G01N2800/2842 , G01N2800/2857 , G01N2800/302 , G01N2800/52 , Y02A50/465 , Y02A50/469
摘要： The present invention is directed to the use of a class of peptide compounds for treating diseases associated with hyperexcitability. The present invention is also directed to the use of a class of peptide compounds for treating diseases associated with dysfunction of an ion channel.
摘要翻译： 本发明涉及一类肽化合物用于治疗与兴奋性相关的疾病的用途。 本发明还涉及一类肽化合物用于治疗与离子通道功能障碍相关的疾病的用途。
-
公开(公告)号：US20100029543A1
公开(公告)日：2010-02-04
申请号：US12577304
申请日：2009-10-12
申请人： Bettina Beyreuther , Thomas Stohr
发明人： Bettina Beyreuther , Thomas Stohr
IPC分类号： A61K38/00
CPC分类号： A61K45/06 , A61K31/165 , A61K38/16 , A61K2300/00
摘要： The present invention is directed to the use of a class of peptide compounds for treating tumor pain, in particular bone cancer pain, for treating chemotherapy-induced pain and for treating nucleoside-induced pain.
摘要翻译： 本发明涉及一类肽化合物用于治疗肿瘤疼痛，特别是骨癌疼痛，用于治疗化疗诱发的疼痛和用于治疗核苷诱导的疼痛的用途。
-
3.发明申请Novel use of peptide compounds for treating bone cancer pain, chemotherapy-and nucleoside-induced pain 失效新型利用肽化合物治疗骨癌，化疗和核苷诱发的疼痛公开(公告)号：US20060046957A1
公开(公告)日：2006-03-02
申请号：US11211476
申请日：2005-08-26
申请人： Bettina Beyreuther , Thomas Stohr
发明人： Bettina Beyreuther , Thomas Stohr
IPC分类号： A61K38/16
CPC分类号： A61K45/06 , A61K31/165 , A61K38/16 , A61K2300/00
摘要： The present invention is directed to the use of a class of peptide compounds for treating tumor pain, in particular bone cancer pain, for treating chemotherapy-induced pain and for treating nucleoside-induced pain.
摘要翻译： 本发明涉及一类肽化合物用于治疗肿瘤疼痛，特别是骨癌疼痛，用于治疗化疗诱发的疼痛和用于治疗核苷诱导的疼痛的用途。
-
4.发明申请6-ARYLAMINO-5-CYANO-4-PYRIMIDINONES AS PDE9A INHIBITORS 审中-公开6-ARYLAMINO-5-CYANO-4-PYRIMIDINONES作为PDE9A抑制剂公开(公告)号：US20090111838A1
公开(公告)日：2009-04-30
申请号：US12339393
申请日：2008-12-19
申请人： Martin HENDRIX , Lars BARFACKER , Bettina BEYREUTHER , Ulrich EBERT , Christina ERB , Frank-Thorsten HAFNER , Heike HECKROTH , Yan-Hong LIU , Dagmar KARTHAUS , Adrian TERSTEEGEN , Franz-Josef VAN DER STAAY , Marja VAN KAMPEN
发明人： Martin HENDRIX , Lars BARFACKER , Bettina BEYREUTHER , Ulrich EBERT , Christina ERB , Frank-Thorsten HAFNER , Heike HECKROTH , Yan-Hong LIU , Dagmar KARTHAUS , Adrian TERSTEEGEN , Franz-Josef VAN DER STAAY , Marja VAN KAMPEN
IPC分类号： A61K31/513 , C07D239/36 , A61P25/00
CPC分类号： C07D239/42 , C07D401/12 , C07D409/12
摘要： The invention relates to novel 6-arylamino-5-cyano-4-pyrimidinones of formula (I) methods for the production thereof, and the use thereof for producing medicaments utilized for improving awareness, concentration, learning capacity, and/or retentiveness of memory. Said compounds (I) show activity as PDE9 inhibitors.
摘要翻译： 本发明涉及式（I）的新型6-芳基氨基-5-氰基-4-嘧啶酮的制备方法及其用于制备用于提高记忆力的意识，浓度，学习能力和/或保持性的药物的用途 。 所述化合物（I）显示作为PDE9抑制剂的活性。
-
5.发明申请公开(公告)号：US20080008748A1
公开(公告)日：2008-01-10
申请号：US11764907
申请日：2007-06-19
IPC分类号： A61K31/381 , A61K31/439 , A61K9/70 , A61P25/04
CPC分类号： A61K31/135 , A61K31/381
摘要： A method for treating pain, particularly non-inflammatory musculoskeletal pain such as fibromyalgia, myofascial pain or back pain, in a subject comprises administering to the subject a substituted 2-aminotetralin compound as defined herein, illustratively rotigotine.
摘要翻译： 用于治疗受试者的疼痛，特别是非炎性肌肉骨骼疼痛如纤维肌痛，肌筋膜疼痛或背部疼痛的方法包括向受试者施用如本文所定义的取代的2-氨基四氢萘酚化合物，例如罗替戈汀。
-
公开(公告)号：US08536137B2
公开(公告)日：2013-09-17
申请号：US12577304
申请日：2009-10-12
申请人： Bettina Beyreuther , Thomas Stöhr
发明人： Bettina Beyreuther , Thomas Stöhr
CPC分类号： A61K45/06 , A61K31/165 , A61K38/16 , A61K2300/00
摘要： The present invention is directed to the use of a class of peptide compounds for treating tumor pain, in particular bone cancer pain, for treating chemotherapy-induced pain and for treating nucleoside-induced pain.
摘要翻译： 本发明涉及一类肽化合物用于治疗肿瘤疼痛，特别是骨癌疼痛，用于治疗化疗诱发的疼痛和用于治疗核苷诱导的疼痛的用途。
-
公开(公告)号：US20080280835A1
公开(公告)日：2008-11-13
申请号：US12063956
申请日：2006-08-18
申请人： Bettina Beyreuther , Thomas Stohr
发明人： Bettina Beyreuther , Thomas Stohr
IPC分类号： A61K38/05 , C07C233/36 , A61P25/00
CPC分类号： A61K31/165 , A61K45/06 , Y02A50/401 , Y02A50/402 , Y02A50/411 , Y02A50/465 , A61K2300/00
摘要： The present invention is directed to the use of a class of peptide compounds for treating non-inflammatory musculoskeletal pain or/and non-inflammatory osteoarthritic pain.
摘要翻译： 本发明涉及一类肽化合物用于治疗非炎性肌肉骨骼疼痛和/和非炎症性骨关节炎的用途。
-
公开(公告)号：US20120225119A1
公开(公告)日：2012-09-06
申请号：US13442212
申请日：2012-04-09
申请人： Bettina Beyreuther , Thomas Stöhr
发明人： Bettina Beyreuther , Thomas Stöhr
IPC分类号： A61K31/4015 , A61P19/02 , A61P29/00 , A61K9/48
CPC分类号： A61K31/165 , A61K45/06 , Y02A50/401 , A61K2300/00
摘要： An embodiment of the present invention relates to a therapeutic combination including (a) lacosamide and/or a pharmaceutically acceptable salt thereof; and (b) levetiracetam and/or a pharmaceutically acceptable salt thereof. The combination can be provided in a single dosage form or separate dosage forms.
摘要翻译： 本发明的一个实施方案涉及治疗组合，其包括（a）lacosamide和/或其药学上可接受的盐; 和（b）左乙拉西坦和/或其药学上可接受的盐。 组合可以以单一剂型或单独的剂型提供。
-
公开(公告)号：US20100324144A1
公开(公告)日：2010-12-23
申请号：US12306953
申请日：2007-06-29
申请人： Cara Heers , Thomas Stoehr , Bettina Beyreuther
发明人： Cara Heers , Thomas Stoehr , Bettina Beyreuther
IPC分类号： A61K31/165 , A61P21/00 , A61P13/12 , A61P25/22
CPC分类号： A61K31/165 , A61K31/19 , A61K31/195 , A61K31/35 , A61K31/4015 , A61K31/4166 , A61K31/53 , A61K31/55 , A61K38/04 , A61K38/05 , A61K45/06 , C12N2503/02 , G01N33/6896 , G01N2500/04 , G01N2800/2835 , G01N2800/2842 , G01N2800/2857 , G01N2800/302 , G01N2800/52 , Y02A50/465 , Y02A50/469
摘要： The present invention is directed to the use of a class of peptide compounds for treating diseases associated with hyperexcitability. The present invention is also directed to the use of a class of peptide compounds for treating diseases associated with dysfunction of an ion channel.
摘要翻译： 本发明涉及一类肽化合物用于治疗与兴奋性相关的疾病的用途。 本发明还涉及一类肽化合物用于治疗与离子通道功能障碍相关的疾病的用途。
-
公开(公告)号：US20100256179A1
公开(公告)日：2010-10-07
申请号：US12752429
申请日：2010-04-01
申请人： Thomas Stöhr , Bettina Beyreuther
发明人： Thomas Stöhr , Bettina Beyreuther
IPC分类号： A61K31/485 , A61P25/02 , A61K31/197 , A61K31/381 , A61K31/165 , A61P31/00
CPC分类号： A61K31/165 , A61K31/16 , A61K38/04 , A61K38/05
摘要： A method for treating pain in painful diabetic neuropathy comprises administering in combination a first agent that comprises a compound as defined herein, illustratively lacosamide, and a second agent effective to provide enhanced treatment of pain, by comparison with the first agent alone. The second agent illustratively comprises an analgesic, an anticonvulsant, an antidepressant or an NMDA receptor antagonist.
摘要翻译： 用于治疗疼痛性糖尿病性神经病变的疼痛的方法包括组合使用包含如本文所定义的化合物（例如，lacosamide）的第一药剂和与单独的第一药物相比有效增强疼痛治疗的第二药剂。 第二药剂包括止痛剂，抗惊厥药，抗抑郁药或NMDA受体拮抗剂。
-
-
-
-
-
-
-
-
-
搜索结果
18 条记录 (耗时 0.016 秒)
