Bacterial and synthetic polysaccharide immunomodulators that enhance general immunity
    2.
    发明授权
    Bacterial and synthetic polysaccharide immunomodulators that enhance general immunity 失效
    细菌和合成多糖免疫调节剂,增强一般免疫力

    公开(公告)号:US06444210B1

    公开(公告)日:2002-09-03

    申请号:US08882398

    申请日:1997-06-25

    IPC分类号: A61K3902

    摘要: The present invention relates to the effects of bacterial polysaccharides on cell mediated immunity in animals. Polysaccharides of the present invention comprise the outer polysaccharides (OPS) located on bacterial cell membranes and other polysaccharides (e.g. “Poly B”) either secreted or contained within the periplasmic space. These polysaccharides have been found to enhance the general or cell mediated immunity of animals to various diseases. The invention provides for the use of such polysaccharides in preventing and treating various infections as well as in treating carcinomas. The invention also provides for synthetic polysaccharides having the same immuno-modulating effect as the bacterial polysaccharides.

    摘要翻译: 本发明涉及细菌多糖对动物细胞介导的免疫的作用。 本发明的多糖包含位于细菌细胞膜上的外多糖(OPS)和在周质空间内分泌或包含的其它多糖(例如“Poly B”)。 已经发现这些多糖增强动物对各种疾病的一般或细胞介导的免疫力。 本发明提供了这种多糖在预防和治疗各种感染以及治疗癌症中的用途。 本发明还提供具有与细菌多糖相同的免疫调节作用的合成多糖。