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公开(公告)号:US20130243734A1
公开(公告)日:2013-09-19
申请号:US13590113
申请日:2012-08-20
IPC分类号: A61K31/711 , A61K35/12 , A61K35/36 , A61K45/06
CPC分类号: A61K31/711 , A61K35/33 , A61K35/36 , A61K38/1754 , A61K38/1825 , A61K38/1841 , A61K38/1858 , A61K45/06 , C12N15/1138 , C12N2310/11 , A61K2300/00
摘要: Methods and compositions comprising combinations of one or more anti-connexin agents and one or more other agents useful for the promotion and/or improvement of wound healing and/or tissue repair.
摘要翻译: 方法和组合物包含一种或多种抗连接蛋白剂和一种或多种用于促进和/或改善伤口愈合和/或组织修复的其它试剂的组合。
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公开(公告)号:US08247384B2
公开(公告)日:2012-08-21
申请号:US11985717
申请日:2007-11-15
IPC分类号: A61K48/00 , A61K31/424
CPC分类号: A61K31/711 , A61K35/33 , A61K35/36 , A61K38/1754 , A61K38/1825 , A61K38/1841 , A61K38/1858 , A61K45/06 , C12N15/1138 , C12N2310/11 , A61K2300/00
摘要: Methods and compositions comprising combinations of one or more anti-connexin agents and one or more other agents useful for the promotion and/or improvement of wound healing and/or tissue repair.
摘要翻译: 包含一种或多种抗连接蛋白剂和一种或多种其它用于促进和/或改善伤口愈合和/或组织修复的其它试剂的组合的方法和组合物。
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公开(公告)号:US20120196799A1
公开(公告)日:2012-08-02
申请号:US13445803
申请日:2012-04-12
CPC分类号: A61K38/22
摘要: Methods for treating obesity are disclosed which comprise administration of a therapeutically effective amount of an amylin or an amylin agonist alone or in conjunction with another obesity relief agent. Additionally, methods for reducing insulin-induced weight gain are disclosed which comprise administration of a therapeutically effective amount of an amylin or an amylin agonist.
摘要翻译: 公开了治疗肥胖症的方法,其包括单独施用治疗有效量的胰岛淀粉样多肽或胰岛淀粉样多肽激动剂或与另一种肥胖症缓解剂联合施用。 此外,公开了减少胰岛素诱导的体重增加的方法,其包括施用治疗有效量的胰岛淀粉样多肽或胰岛淀粉样多肽激动剂。
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公开(公告)号:US08063023B2
公开(公告)日:2011-11-22
申请号:US12001498
申请日:2007-12-11
CPC分类号: C12N15/1138 , A61K31/7105 , C12N2310/11 , C12N2310/14 , C12N2320/35
摘要: Connexin modulation for the treatment of wounds that do not heal at expected rates, including delayed healing wounds, incompletely healing wounds, and chronic wounds, and associated methods, compositions and articles.
摘要翻译: 用于治疗不按预期速率愈合的伤口的连接蛋白调节剂,包括延迟愈合伤口,不完全愈合的伤口和慢性伤口,以及相关方法,组合物和制品。
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公开(公告)号:US20130143952A1
公开(公告)日:2013-06-06
申请号:US13764674
申请日:2013-02-11
IPC分类号: C12N15/113
CPC分类号: C12N15/1138 , A61K31/7105 , C12N2310/11 , C12N2310/14 , C12N2320/35
摘要: Connexin modulation for the treatment of wounds that do not heal at expected rates, including delayed healing wounds, incompletely healing wounds, and chronic wounds, and associated methods, compositions and articles.
摘要翻译: 用于治疗不按预期速率愈合的伤口的连接蛋白调节剂,包括延迟愈合伤口,不完全愈合的伤口和慢性伤口,以及相关方法,组合物和制品。
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公开(公告)号:US20110223204A1
公开(公告)日:2011-09-15
申请号:US12996359
申请日:2009-06-04
IPC分类号: A61K31/7088 , A61K38/02 , A61K9/00 , A61P29/00
CPC分类号: C12N15/1138 , C07K14/705 , C12N2310/11 , C12N2310/14
摘要: The present invention relates to delivery, including transdermal delivery, of a therapeutically effective amount of a compound useful for modulating gap junction formation and function, including an oligonucleotide for reducing gap junction formation and function, and methods and compositions for treating a subject suffering from pain associated with a disease, disorder or condition and associated with pain, including but not limited to muscle pain, ligament pain, tendon pain, joint pain and post-operative pain.
摘要翻译: 本发明涉及治疗有效量的用于调节间隙连接形成和功能的化合物的递送(包括透皮递送),包括用于减少间隙连接形成和功能的寡核苷酸,以及用于治疗患有疼痛的受试者的方法和组合物 与疾病,病症或病症相关并且与疼痛相关,包括但不限于肌肉疼痛,韧带疼痛,肌腱疼痛,关节疼痛和手术后疼痛。
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公开(公告)号:US07910548B2
公开(公告)日:2011-03-22
申请号:US08870762
申请日:1997-06-06
CPC分类号: A61K38/22 , Y10S514/909
摘要: Methods for treating obesity are disclosed which comprise administration of a therapeutically effective amount of an amylin or an amylin agonist alone or in conjunction with another obesity relief agent.
摘要翻译: 公开了治疗肥胖症的方法,其包括单独施用治疗有效量的胰岛淀粉样多肽或胰岛淀粉样多肽激动剂或与另一种肥胖症缓解剂联合施用。
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公开(公告)号:US20090220450A1
公开(公告)日:2009-09-03
申请号:US11985717
申请日:2007-11-15
IPC分类号: A61K38/18 , A61K38/02 , A61K38/19 , A61K38/20 , A61K31/7088 , A61K31/5377 , A61K31/197 , A61K38/12 , A61K31/535 , A61K31/485 , A61P17/02
CPC分类号: A61K31/711 , A61K35/33 , A61K35/36 , A61K38/1754 , A61K38/1825 , A61K38/1841 , A61K38/1858 , A61K45/06 , C12N15/1138 , C12N2310/11 , A61K2300/00
摘要: Methods and compositions comprising combinations of one or more anti-connexin agents and one or more other agents useful for the promotion and/or improvement of wound healing and/or tissue repair.
摘要翻译: 包含一种或多种抗连接蛋白剂和一种或多种其它用于促进和/或改善伤口愈合和/或组织修复的其它试剂的组合的方法和组合物。
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公开(公告)号:US08685940B2
公开(公告)日:2014-04-01
申请号:US13295020
申请日:2011-11-11
CPC分类号: C12N15/1138 , A61K31/7105 , C12N2310/11 , C12N2310/14 , C12N2320/35
摘要: Connexin modulation for the treatment of wounds that do not heal at expected rates, including delayed healing wounds, incompletely healing wounds, and chronic wounds, and associated methods, compositions and articles.
摘要翻译: 用于治疗不按预期速率愈合的伤口的连接蛋白调节剂,包括延迟愈合伤口,不完全愈合的伤口和慢性伤口,以及相关方法,组合物和制品。
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公开(公告)号:US09457044B2
公开(公告)日:2016-10-04
申请号:US13590113
申请日:2012-08-20
IPC分类号: A61K31/70 , A61K31/711 , A61K38/17 , A61K38/18 , C12N15/113 , A61K35/33 , A61K35/36 , A61K45/06 , C12N5/00
CPC分类号: A61K31/711 , A61K35/33 , A61K35/36 , A61K38/1754 , A61K38/1825 , A61K38/1841 , A61K38/1858 , A61K45/06 , C12N15/1138 , C12N2310/11 , A61K2300/00
摘要: Methods and compositions comprising combinations of one or more anti-connexin agents and one or more other agents useful for the promotion and/or improvement of wound healing and/or tissue repair.
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