公开(公告)号：US08370120B2

公开(公告)日：2013-02-05

申请号：US12772155

申请日：2010-04-30

申请人： Brenna Hearn Lord

发明人： Brenna Hearn Lord

IPC分类号： G06G7/48

CPC分类号： A61F2/89 ,  A61F2/82 ,  A61F2240/00 ,  B23K26/38 ,  B23K2101/06 ,  B23K2103/00 ,  B23K2103/42 ,  B23K2103/50 ,  Y10T29/49826

摘要： A pattern is used to form a stent scaffold from a polymeric precursor tube having a particular outer diameter. A new pattern can be derived from a base pattern, wherein the new pattern can be used to form a stent scaffold from a precursor tube having an outer diameter ODPR smaller than that needed for the base pattern. The new pattern can be derived by determining the shape of a stent scaffold, having the base pattern, after having been radially compressed to ODPR. The radially compressed shape is used to design the new pattern, which is applied to a precursor tube having an outer diameter ODPR. The new pattern can have a plurality of W-shaped closed cells, each W-shape closed cell bounded by struts oriented in such a way to form interior angles from about 80 degrees to about 95 degrees between every two adjacent struts.

公开(公告)号：US08303644B2

公开(公告)日：2012-11-06

申请号：US12831440

申请日：2010-07-07

申请人： Brenna Hearn Lord ,  Nicole F. Hou ,  Timothy A. Limon

发明人： Brenna Hearn Lord ,  Nicole F. Hou ,  Timothy A. Limon

IPC分类号： A61F2/82

CPC分类号： A61F2/82 ,  A61F2/0077 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91558 ,  A61F2002/91566 ,  A61F2002/91575 ,  A61F2210/0004 ,  A61F2230/0069 ,  A61F2250/0067 ,  A61L31/06 ,  B26D3/10 ,  B26D7/14 ,  B29C53/02 ,  B29C55/24 ,  B29C67/0014 ,  B29C2793/0009 ,  B29L2031/7534 ,  Y10T29/49826 ,  Y10T29/49925 ,  Y10T83/0424 ,  Y10T156/1043

摘要： Polymeric stents having fracture toughness and resistance to recoil after deployment are disclosed along with methods of manufacturing such stents. Improvements to mechanical characteristics and other improvements may be achieved by having polymer chains within individual stent struts oriented in a direction that is closer to or in line with the axis of the individual stent struts. The struts are connected to each other by hinge elements that are configured to bend during crimping and deployment of the stent. The hinge elements may be tangent or non-tangent to the adjoining struts so as to form W-shaped closed cells arranged in an offset brick pattern in which the size each W-shaped closed cell can be defined in part by a curvilinear length that is approximately 4.5 mm, which allows the stent to be crimped down to an OD of about 1.3 mm and expanded to an OD of at least about 3.5 mm.

摘要翻译： 公开了具有断裂韧性和部署后反冲性的聚合物支架以及制造这种支架的方法。 机械特性和其它改进的改进可以通过使单独的支架支柱内的聚合​​物链沿与单个支架支柱的轴线更接近或一致的方向定向来实现。 支柱通过构造成在支架的压接和展开期间弯曲的铰链元件彼此连接。 铰链元件可以与邻接的支柱相切或非切线，从而形成布置成偏移砖图案的W形闭孔，其中每个W形闭孔的尺寸可以部分地由曲线长度限定， 约4.5mm，其允许支架卷曲到约1.3mm的外径并且扩张至至少约3.5mm的外径。

公开(公告)号：US08852257B2

公开(公告)日：2014-10-07

申请号：US13165662

申请日：2011-06-21

申请人： Annie P. Liu ,  Jason Phillips ,  Mark C. Johnson ,  Brenna Hearn Lord ,  Jeremy Beer ,  Travis Yribarren ,  Steve Saville ,  Marc L. Speck

发明人： Annie P. Liu ,  Jason Phillips ,  Mark C. Johnson ,  Brenna Hearn Lord ,  Jeremy Beer ,  Travis Yribarren ,  Steve Saville ,  Marc L. Speck

IPC分类号： A61F2/84 ,  A61F2/958 ,  A61F2/97 ,  A61F2/82 ,  A61F2/95 ,  A61M25/10

CPC分类号： A61F2/97 ,  A61F2/82 ,  A61F2/958 ,  A61F2002/9522 ,  A61F2002/9583 ,  A61M25/10 ,  A61M2025/1081 ,  Y10T29/49826 ,  Y10T29/49863

摘要： A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. A sheath pair is placed over the crimped scaffold after crimping to reduce recoil of the crimped polymer scaffold and maintain scaffold-balloon engagement relied on to hold the scaffold to the balloon when the scaffold is being delivered to a target in a body. The sheath pair is removed by a health professional before placing the scaffold within the body.

摘要翻译： 医疗装置包括压接到具有膨胀气囊的导管的聚合物构架。 在卷曲之后，将鞘对放置在卷曲框架上方，以减少卷曲聚合物支架的反冲，并且当支架被递送到身体中的目标时，保持脚手架气球接合以将支架保持在气囊上。 在将支架放入体内之前，保健专业人员将护套对移除。

公开(公告)号：US20080009829A1

公开(公告)日：2008-01-10

申请号：US11830104

申请日：2007-07-30

申请人： Diem Ta ,  Caroline WU ,  Brenna Hearn ,  Daniel Cox ,  Leonard Barbod ,  Jessie Delgado ,  Stephen Pacetti ,  Thomas Hatten ,  David Wrolstad ,  Kenneth Armstrong ,  Darrin Kent

发明人： Diem Ta ,  Caroline WU ,  Brenna Hearn ,  Daniel Cox ,  Leonard Barbod ,  Jessie Delgado ,  Stephen Pacetti ,  Thomas Hatten ,  David Wrolstad ,  Kenneth Armstrong ,  Darrin Kent

IPC分类号： A61M31/00 ,  A61F2/06

CPC分类号： A61F2/856 ,  A61F2/91 ,  A61F2/915 ,  A61F2/954 ,  A61F2/958 ,  A61F2002/067 ,  A61F2002/91525 ,  A61F2002/91575 ,  A61F2250/006

摘要： An improved stent design and stent delivery catheter assembly for repairing a main vessel and a side branch vessel forming a bifurcation. The stent includes rings aligned along a common longitudinal axis and connected by links, where the stent has one or more portals for aligning with and partially expanding into the opening to the side branch vessel. The stent is implanted at a bifurcation so that the main stent section is in the main vessel, and the portal section covers at least a portion of the opening to the side branch vessel. A second stent can be implanted in the side branch vessel and abut the expanded central section to provide full coverage of the bifurcated area in the main vessel and the side branch vessel. Radiopaque markers on the stent and on the tip of the delivery catheter assist in aligning the portal section with the opening to the side branch vessel.

摘要翻译： 改进的支架设计和支架输送导管组件，用于修复形成分叉的主血管和侧分支血管。 支架包括沿着共同的纵向轴线对齐并且通过连接件连接的环，其中支架具有用于与侧分支容器的开口对准并部分地扩张的一个或多个门户。 将支架植入分叉处，使得主支架部分在主容器中，并且入口部分覆盖至侧分支容器的开口的至少一部分。 第二支架可以植入侧支血管并且邻接扩张的中心部分以提供主血管和侧支血管中的分叉区域的全面覆盖。 在支架上和输送导管的尖端上的不透射线的标记有助于将门静脉部分与侧支血管的开口对准。

公开(公告)号：US20120324696A1

公开(公告)日：2012-12-27

申请号：US13165662

申请日：2011-06-21

申请人： Annie P. Liu ,  Jason Phillips ,  Mark C. Johnson ,  Brenna Hearn Lord ,  Jeremy Beer ,  Travis Yribarren ,  Steve Saville ,  Marc L. Speck

发明人： Annie P. Liu ,  Jason Phillips ,  Mark C. Johnson ,  Brenna Hearn Lord ,  Jeremy Beer ,  Travis Yribarren ,  Steve Saville ,  Marc L. Speck

IPC分类号： B23P11/00 ,  A61M31/00

CPC分类号： A61F2/97 ,  A61F2/82 ,  A61F2/958 ,  A61F2002/9522 ,  A61F2002/9583 ,  A61M25/10 ,  A61M2025/1081 ,  Y10T29/49826 ,  Y10T29/49863

摘要： A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. A sheath pair is placed over the crimped scaffold after crimping to reduce recoil of the crimped polymer scaffold and maintain scaffold-balloon engagement relied on to hold the scaffold to the balloon when the scaffold is being delivered to a target in a body. The sheath pair is removed by a health professional before placing the scaffold within the body.

摘要翻译： 医疗装置包括压接到具有膨胀气囊的导管的聚合物构架。 在卷曲之后，将鞘对放置在卷曲框架上方，以减少卷曲聚合物支架的反冲，并且当支架被递送到身体中的目标时，保持脚手架气球接合以将支架保持在气囊上。 在将支架放入体内之前，保健专业人员将护套对移除。

公开(公告)号：US20110270384A1

公开(公告)日：2011-11-03

申请号：US12772155

申请日：2010-04-30

申请人： Brenna Hearn Lord

发明人： Brenna Hearn Lord

IPC分类号： A61F2/82 ,  B23P11/00

CPC分类号： A61F2/89 ,  A61F2/82 ,  A61F2240/00 ,  B23K26/38 ,  B23K2101/06 ,  B23K2103/00 ,  B23K2103/42 ,  B23K2103/50 ,  Y10T29/49826

摘要： A pattern is used to form a stent scaffold from a polymeric precursor tube having a particular outer diameter. A new pattern can be derived from a base pattern, wherein the new pattern can be used to form a stent scaffold from a precursor tube having an outer diameter ODPR smaller than that needed for the base pattern. The new pattern can be derived by determining the shape of a stent scaffold, having the base pattern, after having been radially compressed to ODPR. The radially compressed shape is used to design the new pattern, which is applied to a precursor tube having an outer diameter ODPR. The new pattern can have a plurality of W-shaped closed cells, each W-shape closed cell bounded by struts oriented in such a way to form interior angles from about 80 degrees to about 95 degrees between every two adjacent struts.

摘要翻译： 使用图案从具有特定外径的聚合物前体管形成支架支架。 可以从基本图案导出新的图案，其中可以使用新图案从具有小于基底图案所需的外径ODPR的前体管形成支架支架。 可以通过在经径向压缩至ODPR之后确定具有基本图案的支架支架的形状来获得新图案。 径向压缩形状用于设计新的图案，其应用于具有外径ODPR的前体管。 新图案可以具有多个W形封闭单元，每个W形闭合单元以由支柱定向的方式定向，以形成每两个相邻支柱之间的约80度至约95度的内角。

公开(公告)号：US20100274349A1

公开(公告)日：2010-10-28

申请号：US12831440

申请日：2010-07-07

申请人： Brenna Hearn Lord ,  Nicole F. Hou ,  Timothy A. Limon

发明人： Brenna Hearn Lord ,  Nicole F. Hou ,  Timothy A. Limon

IPC分类号： A61F2/82 ,  B32B38/10 ,  B23P11/00

CPC分类号： A61F2/82 ,  A61F2/0077 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91558 ,  A61F2002/91566 ,  A61F2002/91575 ,  A61F2210/0004 ,  A61F2230/0069 ,  A61F2250/0067 ,  A61L31/06 ,  B26D3/10 ,  B26D7/14 ,  B29C53/02 ,  B29C55/24 ,  B29C67/0014 ,  B29C2793/0009 ,  B29L2031/7534 ,  Y10T29/49826 ,  Y10T29/49925 ,  Y10T83/0424 ,  Y10T156/1043

摘要： Polymeric stents having fracture toughness and resistance to recoil after deployment are disclosed along with methods of manufacturing such stents. Improvements to mechanical characteristics and other improvements may be achieved by having polymer chains within individual stent struts oriented in a direction that is closer to or in line with the axis of the individual stent struts. The struts are connected to each other by hinge elements that are configured to bend during crimping and deployment of the stent. The hinge elements may be tangent or non-tangent to the adjoining struts so as to form W-shaped closed cells arranged in an offset brick pattern in which the size each W-shaped closed cell can be defined in part by a curvilinear length that is approximately 4.5 mm, which allows the stent to be crimped down to an OD of about 1.3 mm and expanded to an OD of at least about 3.5 mm.

摘要翻译： 公开了具有断裂韧性和部署后反冲性的聚合物支架以及制造这种支架的方法。 机械特性和其它改进的改进可以通过使单独的支架支柱内的聚合​​物链沿与单个支架支柱的轴线更接近或一致的方向定向来实现。 支柱通过构造成在支架的压接和展开期间弯曲的铰链元件彼此连接。 铰链元件可以与邻接的支柱相切或非切线，从而形成布置成偏移砖图案的W形闭孔，其中每个W形闭孔的尺寸可以部分地由曲线长度限定， 约4.5mm，其允许支架卷曲到约1.3mm的外径并且扩张至至少约3.5mm的外径。