公开(公告)号：US07189354B2

公开(公告)日：2007-03-13

申请号：US10221527

申请日：2001-03-20

申请人： Dianna Innerst ,  Adonis Kassinos ,  C. Benjamin Wooley ,  Brett Wilmarth ,  William J. Sell ,  Emi Zychlinsky ,  Donald Marino ,  Sandy Yamada ,  Renee Ryan ,  Karen Ding ,  Michael Zatzke

发明人： Dianna Innerst ,  Adonis Kassinos ,  C. Benjamin Wooley ,  Brett Wilmarth ,  William J. Sell ,  Emi Zychlinsky ,  Donald Marino ,  Sandy Yamada ,  Renee Ryan ,  Karen Ding ,  Michael Zatzke

IPC分类号： G01N21/00 ,  G01N31/22 ,  G01N15/06 ,  G01N33/00 ,  C12Q1/68

CPC分类号： B01L3/5025 ,  B01L2300/087 ,  B01L2400/0406 ,  G01N21/0303 ,  G01N21/253 ,  G01N21/76 ,  G01N2021/6482 ,  Y10T436/11

摘要： An enclosed chamber is used in a system for screening of a liquid specimen through binding assays. The enclosed chamber includes an inlet, an outlet, and a plurality of discrete reactant containing wells communicated by a common reagent flow path between the inlet and the outlet. A transparent member or coverslip defines on an inside thereof the plurality of wells. Each well has a bottom for receiving an allergent/antigen/reactant, which emits light upon reacting. The coverslip can optionally define at least one lens at each well. A bottom encloses the plurality of wells and defines between the inlet and the outlet a common reagent flow path between the inlet and the outlet. This bottom defines for each of the plurality of wells a flow-diverting member. An opaque partition is disclosed for surrounding the individual lenses and generally isolating the light path from each well.

摘要翻译： 在通过结合测定筛选液体样品的系统中使用封闭室。 封闭室包括入口，出口和多个离散的反应物容纳孔，其通过入口和出口之间的公共试剂流路连通。 透明构件或盖玻片在其内部限定多个孔。 每个井都有一个底部，用于接收过敏原/抗原/反应物，反应会发光。 盖玻片可以可选地在每个孔处限定至少一个透镜。 底部包围多个孔并且在入口和出口之间限定入口和出口之间的公共试剂流动路径。 该底部为多个井中的每一个限定了一个流动分流构件。 公开了一种不透明分隔件，用于围绕各个透镜，并且通常将光路与每个孔隔离。

公开(公告)号：US5409545A

公开(公告)日：1995-04-25

申请号：US27115

申请日：1993-03-04

申请人： William D. Levey ,  William J. Sell ,  Brett Wilmarth

发明人： William D. Levey ,  William J. Sell ,  Brett Wilmarth

IPC分类号： B08B9/20 ,  B08B9/28 ,  B08B9/34 ,  B08B9/44 ,  B08B3/02 ,  B08B9/08

CPC分类号： B08B9/34 ,  B08B9/205 ,  B08B9/28 ,  B08B9/44

摘要： An apparatus and method for cleaning containers, such as sample containers for environmental testing, involves providing modular cleaning bays into which an array of inverted containers can be transported, such as by means of a drive chain. Independently operable nozzle banks disposed in the cleaning bay generally below the resident container tray are driven in an x-axis motion, such as by a stepper motor, to register a selected nozzle bank with successive rows of containers within the tray. At each row of containers the nozzle bank, which is selected in accordance with the size and spacing of the containers being processed, is caused to travel in a z-axis motion through a process cycle in which the nozzle elements of the nozzle bank traverse through the open mouth ends of the containers registered therewith and in which a fluid stream is projected directly onto the interior surfaces of the containers, preferably sweeping the entirety of those surfaces. The tray of containers is exited from the cleaning bay after the last row of containers in the tray is processed. Modular cleaning bays can be cascaded together for processing trays of containers through different washing and rinsing solutions, and for air drying the interior surfaces of the containers.

摘要翻译： 用于清洁容器（例如用于环境测试的样品容器）的装置和方法涉及提供模块化清洁槽，其中可以例如借助于驱动链而将反向容器阵列输送到该清洁槽中。 设置在清洁舱中的独立可操作的喷嘴组通常在常驻容器托盘下方以诸如通过步进电机的x轴运动来驱动，以将选定的喷嘴组与托盘内的连续排的容器对准。 在每排容器中，根据正在处理的容器的尺寸和间距选择的喷嘴组在Z轴运动中通过喷嘴组的喷嘴元件穿过的处理循环而行进 其中记录有容器的开口端部，其中流体流直接投射到容器的内表面上，优选地扫掠这些表面的整体。 在托盘中的最后一排容器被处理之后，容器的托盘从清洁托架中退出。 模块化清洁托架可以级联在一起，以通过不同的洗涤和冲洗溶液处理容器托盘，以及用于空气干燥容器的内表面。