公开(公告)号：US08133518B2

公开(公告)日：2012-03-13

申请号：US12305364

申请日：2007-06-14

申请人： Byung-Hoon Han ,  Mi-Kyung Pyo ,  Eun-Mi Choi ,  Jeong-Won Kim

发明人： Byung-Hoon Han ,  Mi-Kyung Pyo ,  Eun-Mi Choi ,  Jeong-Won Kim

IPC分类号： A23D9/04 ,  C11C3/10

CPC分类号： C11C3/003 ,  A23D9/04 ,  C11C1/005 ,  C11C3/08

摘要： The present invention is concerned with an edible plant oils from which saturated fatty acids were removed and manufacturing process thereof. In order to remove saturated fatty acids from the edible plant oils; 1) Saturated and unsaturated fatty acids bound on same triglyceride molecules of edible plant oils were segregated each other as alkylesters of fatty acids by conventional transesterification reaction in which edible plant oils were treated with large excess of absolute C1˜C8 alkanol under the presence of catalytic amount of alkali- or alkali-earth metal-C1˜C8 alkoxide. 2) The alkyl-esters of mixed fatty acids were treated with C1˜C8 alkanol solution of urea to remove the alkylester of saturated fatty acids by conventional fractional crystallization as urea complexes of saturated fatty acid-alkylesters. 3) Finally the resulting alkylesters of unsaturated fatty acids, obtained by removal of saturated fatty acids by urea complexation procedure, was converted to reconstructed triglyceride oil to give edible plant oils completely devoid of saturated fatty acids. This new manufacturing process could be successfully applied to following 22 kinds of edible plant; 1) corn oil, 2) soybean oil, 3) rapeseed oil, 4) grape seed oil, 5) flaxseed oil, 6) sesame oil, 7) olive oil, 8) perilla oil 9) wall nut oil, 10) pine-nut oil, 11) peanuts oil, 12) sunflower oil, 13) safflower oil, 14) cotton seed oil, 15) palm oil, 16) hot pepper oil, 17) rice bran oil, 18) pumpkin oil, 19) green tea seed oil, 20) almond oil, 21) evening primrose oil and 22) hazelnut oil.

摘要翻译： 本发明涉及去除饱和脂肪酸的食用植物油及其制造方法。 为了从食用植物油中除去饱和脂肪酸; 1）通过常规酯交换反应将可食用植物油的相同甘油三酯分子上的饱和和不饱和脂肪酸彼此分离为脂肪酸的烷基酯，其中食用植物油在催化剂存在下用大量过量的绝对C1〜C8烷醇处理 碱金属或碱土金属-C1〜C8醇盐的用量。 2）混合脂肪酸的烷基酯用尿素的C 1 -C 8烷醇溶液处理，通过常规分级结晶作为饱和脂肪酸 - 烷基酯的尿素复合物除去饱和脂肪酸的烷基酯。 3）最后，通过尿素络合方法除去饱和脂肪酸得到的不饱和脂肪酸烷基酯转化成重建的甘油三酯油，得到完全没有饱和脂肪酸的食用植物油。 这种新的制造工艺可以成功应用于22种食用植物; 1）玉米油，2）大豆油，3）菜籽油，4）葡萄籽油，5）亚麻籽油，6）芝麻油，7）橄榄油，8）紫苏油9）壁坚果油，10） 坚果油，11）花生油，12）向日葵油，13）红花油，14）棉籽油，15）棕榈油，16）辣椒油，17）米糠油，18）南瓜油，19）绿茶 种子油，20）杏仁油，21）月见草油和22）榛子油。

公开(公告)号：US20120315345A1

公开(公告)日：2012-12-13

申请号：US13481995

申请日：2012-05-29

申请人： Byung-Hoon HAN ,  Jeong-Won KIM ,  Sung-Jun JO ,  Hye-Ok CHOI ,  Jung-Hwan KIM ,  Moo-Kang KIM ,  Il-Kwon PARK ,  Seung-Hwan LEE

发明人： Byung-Hoon HAN ,  Jeong-Won KIM ,  Sung-Jun JO ,  Hye-Ok CHOI ,  Jung-Hwan KIM ,  Moo-Kang KIM ,  Il-Kwon PARK ,  Seung-Hwan LEE

IPC分类号： A61K31/12 ,  A23L2/38 ,  A23G3/48 ,  A61P3/04 ,  A21D13/00 ,  A23L1/16 ,  C07C49/573 ,  A61K36/81 ,  A23L1/30 ,  A23L1/10

CPC分类号： A61K36/81 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/12 ,  A61K31/21 ,  A61K36/67 ,  C07C403/14 ,  A23V2200/332 ,  A23V2250/211 ,  A61K2300/00

摘要： One or more embodiments of the present invention describe a novel use of capsanthin and/or fatty-acyl ester of capsanthin to inhibit both the differentiation of pre-adipocytes to adipocytes and the accumulation of fat in the adipocytes. One or more embodiments of the present invention are based on findings that capsanthin contained in some natural products such as red pepper, paprika, bell pepper, etc. have anti-adipogenic activity by inhibiting both the differentiation of pre-adipocyte into adipocyte and the accumulation of fat in adipocytes, Therefore, this findings provide a functional food and a pharmaceutical composition wherein capsanthins and the extract of any natural products containing the same components are included in the functional food and the pharmaceutical composition, to offer obesity prevention and/or treatment effects.

摘要翻译： 本发明的一个或多个实施方案描述了辣椒红和/或辣椒红的脂肪酰基酯的新用途，以抑制前脂肪细胞与脂肪细胞的分化以及脂肪细胞中脂肪的积累。 本发明的一个或多个实施方案基于以下发现：一些天然产物如红辣椒，辣椒红，甜椒等中所含的辣椒红含有通过抑制前脂肪细胞分化成脂肪细胞和积累的脂肪生成活性 脂肪细胞中的脂肪。因此，该发现提供功能性食品和药物组合物，其中将功能性食品和药物组合物中包含辣椒红和含有相同组分的任何天然产物的提取物，以提供肥胖预防和/或治疗效果 。

公开(公告)号：US20090226593A1

公开(公告)日：2009-09-10

申请号：US12305364

申请日：2007-06-14

申请人： Byung-Hoon Han ,  Mi-Kyung Pyo ,  Eun-Mi Choi ,  Jeong-Won Kim

发明人： Byung-Hoon Han ,  Mi-Kyung Pyo ,  Eun-Mi Choi ,  Jeong-Won Kim

IPC分类号： A23D9/00 ,  C12H1/04

CPC分类号： C11C3/003 ,  A23D9/04 ,  C11C1/005 ,  C11C3/08

摘要： The present invention is concerned with an edible plant oils from which saturated fatty acids were removed and manufacturing process thereof. In order to remove saturated fatty acids from the edible plant oils; 1) Saturated and unsaturated fatty acids bound on same triglyceride molecules of edible plant oils were segregated each other as alkylesters of fatty acids by conventional transesterification reaction in which edible plant oils were treated with large excess of absolute C1˜C8 alkanol under the presence of catalytic amount of alkali- or alkali-earth metal-C1˜C8 alkoxide. 2) The alkyl-esters of mixed fatty acids were treated with C1˜C8 alkanol solution of urea to remove the alkylester of saturated fatty acids by conventional fractional crystallization as urea complexes of saturated fatty acid-alkylesters. 3) Finally the resulting alkylesters of unsaturated fatty acids, obtained by removal of saturated fatty acids by urea complexation procedure, was converted to reconstructed triglyceride oil to give edible plant oils completely devoid of saturated fatty acids. This new manufacturing process could be successfully applied to following 22 kinds of edible plant; 1) corn oil, 2) soybean oil, 3) rapeseed oil, 4) grape seed oil, 5) flaxseed oil, 6) sesame oil, 7) olive oil, 8) perilla oil 9) wall nut oil, 10) pine-nut oil, 11) peanuts oil, 12) sunflower oil, 13) safflower oil, 14) cotton seed oil, 15) palm oil, 16) hot pepper oil, 17) rice bran oil, 18) pumpkin oil, 19) green tea seed oil, 20) almond oil, 21) evening primrose oil and 22) hazelnut oil.

摘要翻译： 本发明涉及去除饱和脂肪酸的食用植物油及其制造方法。 为了从食用植物油中除去饱和脂肪酸; 1）通过常规酯交换反应将可食用植物油的相同甘油三酯分子上的饱和不饱和脂肪酸彼此分离为脂肪酸的烷基酯，其中在催化剂存在下用大量过量的绝对C1〜C8链烷醇处理食用植物油 碱金属或碱土金属-C1〜C8醇盐的量。 2）混合脂肪酸的烷基酯用尿素的C 1 -C 8烷醇溶液处理，通过常规分级结晶作为饱和脂肪酸 - 烷基酯的尿素复合物除去饱和脂肪酸的烷基酯。 3）最后，通过尿素络合方法除去饱和脂肪酸得到的不饱和脂肪酸烷基酯转化成重建的甘油三酯油，得到完全没有饱和脂肪酸的食用植物油。 这种新的制造工艺可以成功应用于22种食用植物; 1）玉米油，2）大豆油，3）菜籽油，4）葡萄籽油，5）亚麻籽油，6）芝麻油，7）橄榄油，8）紫苏油9）壁坚果油，10） 坚果油，11）花生油，12）向日葵油，13）红花油，14）棉籽油，15）棕榈油，16）辣椒油，17）米糠油，18）南瓜油，19）绿茶 种子油，20）杏仁油，21）月见草油和22）榛子油。

公开(公告)号：US20050220948A1

公开(公告)日：2005-10-06

申请号：US10509031

申请日：2003-03-24

申请人： Byung-Hoon Han ,  Mi-Kyung Pyo ,  Su-Jin Yang

发明人： Byung-Hoon Han ,  Mi-Kyung Pyo ,  Su-Jin Yang

IPC分类号： A23L1/30 ,  A01G33/00 ,  C12N1/12 ,  A23L1/10

CPC分类号： C12N1/12 ,  A01G33/00 ,  A61K35/748

摘要： Disclosed is a denatured spirulina of being removed the unpleasant smell of spirulina, of maintaining its nutrients undestroyed, of being changed the unpleasant deep blue color from light blue to rose pink, and of showing higher suspensible nature to cold water, characterized in that spirulina is suspended in distilled or purified water to destroy its cell membranes by osmolytic treatment, so the chromoprotein phycocyanin leaks out of the cell membranes; chromoprotein in the spirulina is partially denatured by heating the resulting mixture; condensing, condensing under reduced pressure or finally freeze-dried the resulting mixture.

摘要翻译： 披露了一种变性的螺旋藻，其被去除了螺旋藻的令人不快的气味，维持其营养物质不被破坏，将不愉快的深蓝色从淡蓝色变成玫瑰色粉红色，并且对冷水呈现较高的悬浮性，其特征在于螺旋藻是 悬浮在蒸馏水或纯净水中，通过渗透处理破坏其细胞膜，因此生色蛋白藻蓝蛋白从细胞膜中泄漏出来; 螺旋藻中的色素蛋白通过加热所得混合物而部分变性; 冷凝，减压冷凝或最终冷冻干燥所得混合物。