公开(公告)号：US20220274987A1

公开(公告)日：2022-09-01

申请号：US17632648

申请日：2020-08-20

申请人： CIIMAR -CENTRO INTERDISCIPLINAR DE INVESTIGAÇÃO MARINHA E AMBIENTAL ,  UNIVERSIDADE DO PORTO ,  Universidade Nova De Lisboa

发明人： Maria Emilia DA SILVA PEREIRA DE SOUSA ,  Solida LONG ,  Madalena Maria DE MAGALHAES PINTO ,  Diana RESENDE ,  Anake KIJJOA ,  Paulo Manuel RODRIGUES MARTINS DA COSTA ,  Joana Manuela MACHADO FREITAS DA SILVA ,  Fatima NOGUEIRA

IPC分类号： C07D471/14 ,  C07D487/04 ,  A61K45/06

摘要： The present disclosure relates to pyrazino [1,2-b]quinazoline-3,6-diones compounds, in particular it relates to pyrazino [1,2-b]quinazoline-3,6-diones compounds having antibacterial activity and/or antimalarial activity.

公开(公告)号：US20210379122A1

公开(公告)日：2021-12-09

申请号：US17288383

申请日：2019-10-24

申请人： CIIMAR - CENTRO INTERDISCIPLINAR DE INVESTIGAÇÃO MARINHA E AMBIENTAL ,  UNIVERSIDADE DO PORTO

发明人： Claudia Alexandra DOS REIS SERRA ,  Paula Cristina ENES OLIVEIRA DA SILVA ,  Aires OLIVA TELES ,  Fernando TAVARES

IPC分类号： A61K35/742 ,  C12N1/20 ,  A23K50/80 ,  A23K10/18

摘要： The present disclosure relates to the isolation, identification and characterization of novel sporeforming probiotic strain(s) with NSPase (Non-Starch Polysaccharides-active hydrolases) activity isolated from fish gut microbiota, methods and uses thereof. The sporeforming probiotic strain(s) with NSPase activity now disclosed are able of producing carbohydrate-active enzymes (CAZymes) that hydrolyse non-starch polysaccharides (NSPs) and accesses their potential as probiotics (PRO) for use in particular in aquafeeds.