公开(公告)号：US5473098A

公开(公告)日：1995-12-05

申请号：US398840

申请日：1995-03-06

申请人： Richard H. S. Wang ,  Carl A. Bryan, Jr. ,  Bill A. Eller

发明人： Richard H. S. Wang ,  Carl A. Bryan, Jr. ,  Bill A. Eller

IPC分类号： C07B61/00 ,  C07C67/343 ,  C07C69/76 ,  C07F9/141

CPC分类号： C07C67/343

摘要： Disclosed is a process for the preparation of 4,4'-stilbenedicarboxylate esters by a 4-step process starting with an alkyl p-formylbenzoate and utilizing intermediate phosphite and phosphonate compounds. The steps comprise(1) preparing an alkyl p-(hydroxymethyl)benzoate by hydrogenating an alkyl p-formylbenzoate;(2) contacting the alkyl p-(hydroxymethyl)benzoate of step (1) with a trialkyl phosphite to obtain a phosphite ester compound having the formula: ##STR1## (3) contacting the phosphite ester of step (2) with a catalytic amount of iodine to rearrange the phosphite ester to the corresponding phosphonate ester;and(4) contacting the phosphonate ester compound of step (3) with an alkyl p-formylbenzoate in the presence of an alkali metal alkoxide and an inert solvent to obtain the dialkyl 4,4'-stilbenedicarboxylate.

摘要翻译： 公开了一种通过四步法由对位甲酰基苯甲酸烷基酯和利用中间体亚磷酸酯和膦酸酯化合物制备4,4'-二苯乙烯二羧酸酯的方法。 步骤包括（1）通过氢化对甲酰基苯甲酸烷基酯制备对 - （羟甲基）苯甲酸烷基酯; （2）使步骤（1）的对 - （羟甲基）苯甲酸烷基酯与亚磷酸三烷基酯接触，得到具有下式的亚磷酸酯化合物：（3）使步骤（2）的亚磷酸酯与催化量 的碘以将亚磷酸酯重排为相应的膦酸酯; 和（4）在碱金属醇盐和惰性溶剂的存在下使步骤（3）的膦酸酯化合物与对甲酰基苯甲酸烷基酯接触，得到4,4'-二苯乙烯二酸二烷基酯。