公开(公告)号：US20230234977A1

公开(公告)日：2023-07-27

申请号：US18130133

申请日：2023-04-03

申请人： Universite de Bordeaux ,  Institut Polytechnique de Bordeaux ,  Centre National de la Recherche Scientifique (CNRS)

发明人： Mathieu Pucheault ,  Virginie Liautard ,  Loic Guillonneau ,  Olivier Guerret

IPC分类号： C07F9/141

CPC分类号： C07F9/141 ,  C07B2200/09 ,  C07C69/587

摘要： The present invention relates to a process for preparing a mixture M1 of enol phosphate isomers devoid of (E,E) isomer and comprising at least 98% of (E,Z) isomer, at least 0.1% of (Z,Z) isomer and at least 0.1% of (Z,E) isomer, comprising bringing a mixture of isomers of said enol phosphate comprising a detectable amount of (E,E) isomer into contact with a hydrolysable dienophile in an organic solvent, followed by base hydrolysis of the medium obtained and elimination of the adduct formed, in order to obtain the mixture M1 devoid of (E,E) isomer.

公开(公告)号：US11649257B2

公开(公告)日：2023-05-16

申请号：US16492256

申请日：2018-03-09

申请人： Universite de Bordeaux ,  Institut Polytechnique de Bordeaux ,  Centre National de la Recherche Scientifique (CNRS)

发明人： Mathieu Pucheault ,  Virginie Liautard ,  Loic Guillonneau ,  Olivier Guerret

IPC分类号： C07F9/141 ,  C07C69/587

CPC分类号： C07F9/141 ,  C07B2200/09 ,  C07C69/587

摘要： The present invention relates to a process for preparing a mixture M1 of enol phosphate isomers devoid of (E,E) isomer and comprising at least 98% of (E,Z) isomer, at least 0.1% of (Z,Z) isomer and at least 0.1% of (Z,E) isomer, comprising bringing a mixture of isomers of said enol phosphate comprising a detectable amount of (E,E) isomer into contact with a hydrolysable dienophile in an organic solvent, followed by base hydrolysis of the medium obtained and elimination of the adduct formed, in order to obtain the mixture M1 devoid of (E,E) isomer.

公开(公告)号：US20220380356A1

公开(公告)日：2022-12-01

申请号：US17763438

申请日：2020-09-25

申请人： MEDSHINE DISCOVERY INC.

发明人： Yaxun YANG ,  Zhigan JIANG ,  Jianhua XIA ,  Wei WEI ,  Haiying HE ,  Shuhui CHEN

IPC分类号： C07D413/04 ,  C07D413/14 ,  C07D405/04 ,  C07D401/04 ,  C07D417/14 ,  C07F9/141

摘要： A class of compounds that have a pyrazine structure, specifically disclosed is a compound represented by formula, isomers or pharmaceutically acceptable salts thereof, and an application thereof in the preparation of CRAC inhibitors.

公开(公告)号：US20210347794A1

公开(公告)日：2021-11-11

申请号：US17278579

申请日：2019-09-23

申请人： ARIAGEN, INC.

发明人： Graham Johnson ,  David Douglas Manning

IPC分类号： C07F9/24 ,  C07F9/141 ,  A61P35/00

摘要： The present disclosure relates to phosphate derivatives of indole compounds and pharmaceutical compositions thereof, and their use in stimulating the immune system of patients such as cancer patients.

公开(公告)号：US20210284667A1

公开(公告)日：2021-09-16

申请号：US17193531

申请日：2021-03-05

申请人： SAMSUNG ELECTRONICS CO., LTD.

发明人： Seungmin RYU ,  Jaewoon KIM ,  Gyuhee PARK ,  Younjoung CHO ,  Kazuya SAITO ,  Takanori KOIDE ,  Yoshiki MANABE ,  Yutaro AOKI ,  Hiroyuki UCHIUZOU ,  Wakana FUSE

IPC分类号： C07F9/141 ,  C23C16/18 ,  H01L21/285

摘要： An organometallic adduct compound and a method of manufacturing an integrated circuit (IC) device, the organometallic adduct compound being represented by General formula (I): in General formula (I), R1, R2, and R3 are each independently a C1 to C5 alkyl group, at least one of R1, R2, and R3 being a C1 to C5 alkyl group in which at least one hydrogen atom is substituted with a fluorine atom, M is a niobium atom, a tantalum atom, or a vanadium atom, X is a halogen atom, m is an integer of 3 to 5, and n is 1 or 2.

公开(公告)号：US20210075063A1

公开(公告)日：2021-03-11

申请号：US17056740

申请日：2019-12-13

申请人： Contemporary Amperex Technology Co., Limited

发明人： Shushi Dou ,  Chunhua Hu ,  Tiancheng Yi ,  Yao Jiang ,  Chengdu Liang

IPC分类号： H01M10/0567 ,  H01M10/0525 ,  H01M4/525 ,  H01M4/48 ,  H01M4/38 ,  H01M4/587 ,  H01M4/36 ,  C07D239/04 ,  C07D251/04 ,  C07F9/09 ,  C07F9/141

摘要： This application provides a lithium-ion battery and an apparatus. The lithium-ion battery includes an electrode assembly and an electrolyte. The electrode assembly includes a positive electrode plate, a negative electrode plate, and a separator. A positive active material of the positive electrode plate includes Lix1Coy1M1-y1O2-z1Qz1, where 0.5≤x1≤1.2, 0.8≤y1≤1.0, 0≤z1≤0.1, M is selected from one or more of Al, Ti, Zr, Y, and Mg, and Q is selected from one or more of F, Cl, and S. The electrolyte contains an additive A, an additive B, and an additive C. The additive A is a polynitrile six-membered nitrogen-heterocyclic compound with a relatively low oxidation potential. The additive B is a silyl phosphite compound or a silyl phosphate compound or a mixture thereof. The additive C is a halogen substituted cyclic carbonate compound.

公开(公告)号：US10745425B2

公开(公告)日：2020-08-18

申请号：US16314388

申请日：2016-07-01

申请人： SHENZHEN YHLO BIOTECH CO., LTD.

发明人： Kunhui Hu ,  Gang Wang ,  Fuzhen Xia ,  Chungen Qian ,  Liang Zhu ,  Dingbiao Zou

IPC分类号： G01N21/76 ,  C07F9/09 ,  C07F9/141 ,  C08K5/19 ,  C09K11/07

摘要： Disclosed a chemiluminescence enhancer and a chemiluminescence immunodetection kit. The chemiluminescence enhancer is specifically a betaine and can be used for enhancing the luminance of a luminescent acridine substance. The chemiluminescence immunodetection kit comprising the chemiluminescence enhancer and a luminescent acridine substance features greatly enhanced luminescence signals and high detection sensibility, and can be widely applied to fields such as clinical diagnoses, scientific research, and sanitation analysis.

公开(公告)号：US10388953B2

公开(公告)日：2019-08-20

申请号：US15531656

申请日：2015-11-27

申请人： SUMITOMO METAL MINING CO., LTD.

发明人： Ryosuke Okamoto ,  Kazuhiko Okubo

IPC分类号： H01M4/58 ,  H01M4/131 ,  H01M10/0525 ,  C01G53/00 ,  H01M4/36 ,  H01M4/505 ,  H01M4/525 ,  C01B25/40 ,  C07F9/09 ,  C07F9/141

摘要： Provided are a lithium-manganese-nickel composite oxide carrying an organic phosphate with a high capacity and a high cycle characteristic when used as a positive electrode active material of a secondary battery, a method for producing the same, and also a nonaqueous electrolyte secondary battery using the lithium-manganese-nickel composite oxide as a positive electrode active material. The positive electrode active material for a nonaqueous electrolyte secondary battery, wherein an organic phosphite compound or an organic phosphate compound having an organic functional group composed of an alkyl group, an aryl group, and the like adheres to a part or the entire of a particle surface of the lithium-manganese-nickel composite oxide represented by general formula: LitMn2-x-yNixMyO4 (wherein 0.96

公开(公告)号：US10301436B2

公开(公告)日：2019-05-28

申请号：US15611360

申请日：2017-06-01

申请人： International Business Machines Corporation

发明人： Sarah K. Czaplewski ,  Brandon M. Kobilka ,  Joseph Kuczynski ,  Jason T. Wertz ,  Jing Zhang

IPC分类号： C08K5/521 ,  C08K5/524 ,  C07F9/02 ,  C08G81/02 ,  C08G18/83 ,  H05K1/03 ,  C07F9/113 ,  C07C69/007 ,  C07F9/141 ,  C07F9/09 ,  C07C69/003 ,  C08K5/00

摘要： A flame-retardant aconitic acid-derived cross-linker, a process for forming a flame-retardant resin, and an article of manufacture comprising a material that contains a flame-retardant aconitic acid-derived cross-linker are disclosed. The flame-retardant aconitic acid-derived cross-linker can have at least two phosphoryl or phosphonyl moieties with allyl functional groups, epoxy functional groups, propylene carbonate functional group, or functionalized thioether substituents. The process for forming the flame-retardant polymer can include forming an aconitic acid derivative, forming a phosphorus-based flame-retardant molecule, and reacting the aconitic acid derivative with the phosphorus-based flame-retardant molecule to form a flame-retardant aconitic acid-derived cross-linker, and binding the cross-linker to a polymer. The aconitic acid derivative can be synthesized from aconitic acid obtained from a bio-based source. Examples of aconitic acid derivatives include carboxysuccinic acid, 2-(hydroxymethyl)-1,4-butenediol, and 2-(hydroxymethyl)-1,4-butanediol. The article of manufacture can further comprise an electronic component.

公开(公告)号：US10301406B2

公开(公告)日：2019-05-28

申请号：US15611423

申请日：2017-06-01

申请人： International Business Machines Corporation

发明人： Sarah K. Czaplewski ,  Brandon M. Kobilka ,  Joseph Kuczynski ,  Jason T. Wertz ,  Jing Zhang

IPC分类号： C08K5/521 ,  C08K5/524 ,  C07F9/02 ,  C08F130/02 ,  C08G79/04 ,  C09J9/00 ,  C09J143/02 ,  C09J185/02 ,  H05K1/03 ,  H01B3/30 ,  C07F9/655 ,  C07F9/12 ,  C07F9/40 ,  C07F9/141 ,  C07F9/113 ,  C08K5/00 ,  C07F9/09 ,  C07C69/07 ,  C07C69/003

摘要： A flame-retardant aconitic acid-derived monomer, a process for forming a flame-retardant polymer, and an article of manufacture comprising a material that contains a flame-retardant aconitic acid-derived monomer are disclosed. The flame-retardant aconitic acid-derived monomer can have at least one phosphoryl or phosphonyl moiety with functional groups that can participate in a polymerization reaction, such as allyl, epoxy, or propylene carbonate functional groups. The process for forming the flame-retardant polymer can include forming an aconitic acid derivative, forming a phosphorus-based flame-retardant molecule, and reacting the aconitic acid derivative with the phosphorus-based flame-retardant molecule to form a flame-retardant aconitic acid-derived monomer, which is then polymerized. The aconitic acid derivative can be synthesized from aconitic acid obtained from a bio-based source. The material in the article of manufacture can be a resin or adhesive, and the article of manufacture can further comprise an electronic component.