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1.发明授权Poly(alpha-hydroxy acrylic acid) and derivatives as antitartar actives in oral compositions 失效聚（α-羟基丙烯酸）和衍生物作为口服组合物中的抗缬氨酸活性物质
公开(公告)号：US5013541A
公开(公告)日：1991-05-07
申请号：US510652
申请日：1990-04-18
IPC分类号： A61K8/00 , A61K8/21 , A61K8/34 , A61K8/73 , A61K8/81 , A61K8/86 , A61K31/78 , A61K47/10 , A61K47/34 , A61K47/36 , A61P1/02 , A61Q11/00
CPC分类号： A61Q11/00 , A61K8/8147
摘要： An oral composition is provided which reduces formation of tartar on teeth. The active ingredient is poly(.alpha.-hydroxy acrylic acid) as well as phosphate, sulfate and alkoxy derivatives thereof.
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公开(公告)号：US5011682A
公开(公告)日：1991-04-30
申请号：US510651
申请日：1990-04-18
CPC分类号： A61K8/8147 , A61K8/24 , A61K8/8164 , A61Q11/00 , A61K2800/57
摘要： A method and composition for controlling tartar formation in the mouth is reported based upon low molecular weight polymers. These polymers are formed from a mixture of mono- and di- carboxylic vinyl monomers reacted with hypophosphite groups. Particularly effective are phosphorus containing acrylate/maleate polymers of weight averaged molecular weight ranging from about 400 to 5000.
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公开(公告)号：US5194246A
公开(公告)日：1993-03-16
申请号：US686106
申请日：1991-04-16
CPC分类号： A61K8/8164 , A61K8/8147 , A61Q11/00 , A61K2800/594
摘要： A method and composition for controlling calculus formation in the mouth is reported based upon a combination of a low and high molecular weight polymer. The first polymer is a synthetic anionic polymer having a molecular weight of at least 4000. The second polymer has a molecular weight up to about 2500 and is formed from a mixture of mono- and di- carboxylic vinyl monomers reacted with hypophosphite groups.
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4.发明授权
公开(公告)号：US5143719A
公开(公告)日：1992-09-01
申请号：US686208
申请日：1991-04-16
CPC分类号： A61K8/8164 , A61K8/24 , A61Q11/00 , A61K2800/57
摘要： A method and composition for controlling calculus formation in the mouth is reported based upon a combination of inorganic polyphosphates and certain low molecular weight copolymers. These copolymers are formed from a mixture of mono- and di-carboxylic vinyl monomers reacted with hypophosphite groups. Particularly effective are phosphorous containing acrylate/maleate polymers of weight averaged molecular weight ranging from about 400 to 5000.
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