公开(公告)号：US20240279349A2

公开(公告)日：2024-08-22

申请号：US17836473

申请日：2022-06-09

Applicant: Sanjaya Singh ,  Alisa Waterman ,  Erik Depla ,  Toon Laeremans ,  Diane Van Hoorick ,  Cedric Ververken

Inventor： Sanjaya Singh ,  Alisa Waterman ,  Erik Depla ,  Toon Laeremans ,  Diane Van Hoorick ,  Cedric Ververken

IPC: C07K16/28 ,  C07H21/04 ,  C12N15/09 ,  C12N15/11 ,  C12N15/63 ,  A61K39/00 ,  A61K39/395 ,  A61P13/12 ,  C07K14/52 ,  C07K14/715

CPC classification number: C07K16/2866 ,  C07H21/04 ,  C07K16/28 ,  C12N15/09 ,  C12N15/11 ,  C12N15/63 ,  A61K39/3955 ,  A61K2039/505 ,  A61P13/12 ,  C07K14/521 ,  C07K14/7158 ,  C07K2317/22 ,  C07K2317/24 ,  C07K2317/30 ,  C07K2317/35 ,  C07K2317/52 ,  C07K2317/565 ,  C07K2317/569 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2317/94 ,  C07K2319/00 ,  C07K2319/30

Abstract: The present invention relates to CX3CR1-binding polypeptides, in particular polypeptides comprising specific immunoglobulin domains. The invention also relates to nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to host cells expressing or capable of expressing such polypeptides; to compositions comprising such polypeptides; and to uses of such polypeptides or such compositions, in particular for prophylactic, therapeutic and diagnostic purposes.