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公开(公告)号:US07494472B2
公开(公告)日:2009-02-24
申请号:US10746950
申请日:2003-12-23
申请人: Robert Sakal , Ellen E. Sheets , Meghan Brennan , Greg R. Furnish , Charles H. Whatley, Jr. , Ben E. Morris , Indi Gunasekara
发明人: Robert Sakal , Ellen E. Sheets , Meghan Brennan , Greg R. Furnish , Charles H. Whatley, Jr. , Ben E. Morris , Indi Gunasekara
IPC分类号: A61B10/00
CPC分类号: A61M25/0068 , A61B10/0041 , A61B10/0045 , A61B17/3421 , A61B2017/22074 , A61B2217/005 , A61M25/008 , A61M2025/0073
摘要: A ductal access device is provided for accessing a breast duct and collecting biological material from within the duct. The access device may include an elongated member having an outer diameter sized for positioning within the breast duct and an internal lumen for infusing a fluid into the breast duct and collecting fluid from the breast duct. The elongated member may include a central axis extending through the internal lumen and a different axis being parallel to the central axis defining an off-axis configuration. An elongated distal tip extends beyond the distal end of the internal lumen and along the different axis. The elongated distal tip has a closed distal end for navigating within the breast duct. The elongated distal tip may include an internal passageway that is sized to slidiably or removably receive an elongated introducer.
摘要翻译: 提供导管进入装置用于进入乳房管道并从管道内收集生物材料。 进入装置可以包括细长构件,其具有尺寸适于定位在乳房管道内的外径和用于将流体输入乳房管道并从乳房管道收集流体的内腔。 细长构件可以包括延伸穿过内部内腔的中心轴线,并且不同的轴线平行于限定离轴构造的中心轴线。 细长的远端尖端延伸超过内腔的远端并沿着不同的轴线。 细长的远侧末端具有用于在乳房导管内导航的封闭远端。 细长的远侧末端可以包括内部通道,其尺寸设计成可滑动地或可移除地容纳细长的导引器。
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公开(公告)号:US07229420B2
公开(公告)日:2007-06-12
申请号:US10746128
申请日:2003-12-23
CPC分类号: A61M1/0058 , A61B10/0041 , A61B10/0045 , A61B2090/034
摘要: A medical instrument including a ductal access device comprising a low profile, ergonomic manifold hub usable to introduce fluids into a breast duct and collect ductal fluid samples including ductal epithelial cells and clumps of ductal epithelial cells from within a breast duct. The ductal access device also comprises an elongated access catheter having a distal end, one lumen and dimensions which permit introduction of the distal end through a ductal orifice so that a distal end of the catheter may be positioned distal to the ductal sphincter of a human breast. The medical instrument may also include at least one spacing member for adjustably positioning the manifold hub a desired distance above the surface of the nipple. The spacing member may control the insertion depth of the catheter into the duct. The medical instrument may also include at least one member for anchoring the device to the breast.
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公开(公告)号:US07125414B2
公开(公告)日:2006-10-24
申请号:US10336646
申请日:2003-01-02
申请人: Victor R. Blackledge , Charles H. Whatley, Jr. , Benjamin E. Morris , Todd A. Hall , William A. Reuss, Jr.
发明人: Victor R. Blackledge , Charles H. Whatley, Jr. , Benjamin E. Morris , Todd A. Hall , William A. Reuss, Jr.
IPC分类号: A61M29/00
CPC分类号: A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0067
摘要: An emboli filter for deployment in a body lumen to capture emboli entrained in a fluid flowing through the lumen includes a flexible elongated member sized to be passed through the lumen. A filter media is carried on and substantially surrounding the elongated member. The filter media has a first end secured to the elongated member adjacent the distal end. A second end of the filter media has a periphery movable toward and away from the elongated member. Opposing internal surfaces of the filter media define a volume into which emboli may flow through the second end when the periphery is moved away from the elongated member. The emboli are trapped within the volume when the periphery is moved toward the elongated member. An actuator moves the periphery toward and way from the elongated member. The actuator includes a plurality of elastic loops. The loops are biased to an open loop configuration with the loops urging the periphery away from the elongated member. The actuator is adapted to be manipulated by an operator to urge the loops against the bias to a closed position permitting movement of the periphery toward the elongated member without interference from the loops.
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公开(公告)号:US06520978B1
公开(公告)日:2003-02-18
申请号:US09570659
申请日:2000-05-15
申请人: Victor R. Blackledge , Charles H. Whatley, Jr. , Benjamin E. Morris , Todd A. Hall , William A. Reuss, Jr.
发明人: Victor R. Blackledge , Charles H. Whatley, Jr. , Benjamin E. Morris , Todd A. Hall , William A. Reuss, Jr.
IPC分类号: A61M2900
CPC分类号: A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0067
摘要: An emboli filter for deployment in a body lumen to capture emboli entrained in a fluid flowing through the lumen includes a flexible elongated member sized to be passed through the lumen. A filter media is carried on and substantially surrounding the elongated member. The filter media has a first end secured to the elongated member adjacent the distal end. A second end of the filter media has a periphery movable toward and away from the elongated member. Opposing internal surfaces of the filter media define a volume into which emboli may flow through the second end when the periphery is moved away from the elongated member. The emboli are trapped within the volume when the periphery is moved toward the elongated member. An actuator moves the periphery toward and way from the elongated member. The actuator includes a plurality of elastic loops. The loops are biased to an open loop configuration with the loops urging the periphery away from the elongated member. The actuator is adapted to be manipulated by an operator to urge the loops against the bias to a closed position permitting movement of the periphery toward the elongated member without interference from the loops.
摘要翻译: 用于部署在体腔中的栓塞过滤器以捕获夹带在流过管腔的流体中的栓塞,包括尺寸适于通过内腔的柔性细长构件。 过滤介质被承载并且基本上围绕细长构件。 过滤介质的第一端固定在与远端相邻的细长构件上。 过滤介质的第二端具有朝向和远离细长构件移动的周边。 过滤介质的相对的内表面限定了一个体积,当周边移动离开细长构件时,栓塞可以流经第二端。 当周边朝向细长构件移动时,栓塞被捕获在体积内。 致动器使周边朝向和远离细长构件移动。 致动器包括多个弹性环。 这些环被偏压到开环构型,其中环使得周边远离细长构件。 致动器适于由操作者操纵以将回路抵抗偏压推动到关闭位置,允许周边朝向细长构件移动而不受到环的干扰。
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