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公开(公告)号：US07229420B2
公开(公告)日：2007-06-12
申请号：US10746128
申请日：2003-12-23
CPC分类号： A61M1/0058 , A61B10/0041 , A61B10/0045 , A61B2090/034
摘要： A medical instrument including a ductal access device comprising a low profile, ergonomic manifold hub usable to introduce fluids into a breast duct and collect ductal fluid samples including ductal epithelial cells and clumps of ductal epithelial cells from within a breast duct. The ductal access device also comprises an elongated access catheter having a distal end, one lumen and dimensions which permit introduction of the distal end through a ductal orifice so that a distal end of the catheter may be positioned distal to the ductal sphincter of a human breast. The medical instrument may also include at least one spacing member for adjustably positioning the manifold hub a desired distance above the surface of the nipple. The spacing member may control the insertion depth of the catheter into the duct. The medical instrument may also include at least one member for anchoring the device to the breast.
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公开(公告)号：US07494472B2
公开(公告)日：2009-02-24
申请号：US10746950
申请日：2003-12-23
申请人： Robert Sakal , Ellen E. Sheets , Meghan Brennan , Greg R. Furnish , Charles H. Whatley, Jr. , Ben E. Morris , Indi Gunasekara
发明人： Robert Sakal , Ellen E. Sheets , Meghan Brennan , Greg R. Furnish , Charles H. Whatley, Jr. , Ben E. Morris , Indi Gunasekara
IPC分类号： A61B10/00
CPC分类号： A61M25/0068 , A61B10/0041 , A61B10/0045 , A61B17/3421 , A61B2017/22074 , A61B2217/005 , A61M25/008 , A61M2025/0073
摘要： A ductal access device is provided for accessing a breast duct and collecting biological material from within the duct. The access device may include an elongated member having an outer diameter sized for positioning within the breast duct and an internal lumen for infusing a fluid into the breast duct and collecting fluid from the breast duct. The elongated member may include a central axis extending through the internal lumen and a different axis being parallel to the central axis defining an off-axis configuration. An elongated distal tip extends beyond the distal end of the internal lumen and along the different axis. The elongated distal tip has a closed distal end for navigating within the breast duct. The elongated distal tip may include an internal passageway that is sized to slidiably or removably receive an elongated introducer.
摘要翻译： 提供导管进入装置用于进入乳房管道并从管道内收集生物材料。 进入装置可以包括细长构件，其具有尺寸适于定位在乳房管道内的外径和用于将流体输入乳房管道并从乳房管道收集流体的内腔。 细长构件可以包括延伸穿过内部内腔的中心轴线，并且不同的轴线平行于限定离轴构造的中心轴线。 细长的远端尖端延伸超过内腔的远端并沿着不同的轴线。 细长的远侧末端具有用于在乳房导管内导航的封闭远端。 细长的远侧末端可以包括内部通道，其尺寸设计成可滑动地或可移除地容纳细长的导引器。
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3.发明授权Ductal lavage microcatheter with user activated valve and Nitinol introducer 有权导管灌洗微导管与用户激活阀和镍钛杆菌导引器公开(公告)号：US07276047B2
公开(公告)日：2007-10-02
申请号：US10746117
申请日：2003-12-23
申请人： Robert Sakal , Meghan Brennan , Douglas Macarthur , Ben E. Morris , Todd A. Hall , Simon Furnish
发明人： Robert Sakal , Meghan Brennan , Douglas Macarthur , Ben E. Morris , Todd A. Hall , Simon Furnish
CPC分类号： A61M25/01 , A61B10/0041 , A61B10/0045 , A61M25/0102 , A61M39/06 , A61M2025/0042 , A61M2210/1007
摘要： A medical instrument including a ductal access device comprising a low profile, ergonomic manifold hub usable to introduce fluids into a breast duct and collect ductal fluid samples including ductal epithelial cells and clumps of ductal epithelial cells from within a breast duct. The ductal access device also comprises an elongated access catheter having a distal end, one lumen and dimensions which permit introduction of the distal end through a ductal orifice so that a distal end of the catheter may be positioned distal to the ductal sphincter of a human breast. The medical instrument may also include and activate valve and a Nitinol introducer.
摘要翻译： 一种医疗器械，其包括导管进入装置，其包括用于将流体引入乳房导管中的低轮廓人体工程学的歧管轮毂，并从乳房导管内收集包括导管上皮细胞和导管上皮细胞团的导管流体样品。 导管进入装置还包括细长的进入导管，其具有远端，一个内腔和尺寸，其允许远端通过导管孔引入，使得导管的远端可位于人乳房的导管括约肌的远侧 。 医疗器械还可以包括并激活阀和镍钛诺导入器。
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