公开(公告)号：US20060287231A1

公开(公告)日：2006-12-21

申请号：US11436059

申请日：2006-05-18

申请人： Chee-Wui Chu ,  ZhongQi Shao ,  Quan Yang ,  Genevieve Huppe

发明人： Chee-Wui Chu ,  ZhongQi Shao ,  Quan Yang ,  Genevieve Huppe

IPC分类号： A61K38/17

CPC分类号： A61K38/4853

摘要： The present invention relates to therapeutic applications of kallikreins and compositions containing them for treating, preventing and/or ameliorating cancers, especially epithelial cancers, such as ovarian, breast and cervical cancer.

摘要翻译： 本发明涉及激肽释放酶及其组合物的治疗应用，用于治疗，预防和/或改善癌症，特别是卵巢癌，乳腺癌和子宫颈癌等上皮癌。

公开(公告)号：US06636623B2

公开(公告)日：2003-10-21

申请号：US10145982

申请日：2002-05-14

申请人： Alan C. Nelson ,  Robert W. Webster ,  Chee-Wui Chu

发明人： Alan C. Nelson ,  Robert W. Webster ,  Chee-Wui Chu

IPC分类号： G06K900

CPC分类号： G01N33/5091 ,  G01N15/1475 ,  G01N23/046 ,  G01N33/574 ,  G01N2015/1006 ,  G01N2223/419 ,  G06K9/00127 ,  G06T7/0012 ,  G06T2207/10152 ,  G06T2207/30024

摘要： A system and method for rapidly detecting cells associated with malignancy and disease using molecular marker compartmentalization includes an optical tomography (OT) or a flow optical tomography (FOT) instrument capable of producing various optical projection images (or shadowgrams) containing accurate density information from a cell or cells labeled with tagged molecular probes or stains, a computer and software to analyze and reconstruct the projection images into a multi-dimensional data set, and automated feature collection and object classifiers. The system and method are particularly useful in the early detection of cancers such as lung cancer using cells from sputum or cheek scrapings and cervical/ovarian cancer using a cervical scraping, and the system can be used to detect rare cells in specimens including blood.

公开(公告)号：US06591003B2

公开(公告)日：2003-07-08

申请号：US10260908

申请日：2002-09-30

申请人： Chee-Wui Chu ,  Alan C. Nelson

发明人： Chee-Wui Chu ,  Alan C. Nelson

IPC分类号： G06K900

CPC分类号： G01N23/046 ,  G01N15/147 ,  G01N21/05 ,  G01N21/4795 ,  G01N2223/419 ,  G06T11/006

摘要： Three dimensional reconstruction of an object of interest moving at a constant velocity. The object of interest is centered. The object of interest is imaged with optical point sources located at multiple projection angles around the object of interest, in cooperation with opposing time delay and integration (TDI) image sensors located at a distance from the objects of interest such that there is no focal plane within the objects of interest during imaging. Each of the TDI sensors has a line transfer rate synchronized to the constant velocity of the objects of interest.