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公开(公告)号:US20180105927A1
公开(公告)日:2018-04-19
申请号:US15351155
申请日:2016-11-14
申请人: Fook Chi MAK , Sai Chi MAK
发明人: Fook Chi MAK , Sai Chi MAK
CPC分类号: C23C14/3464 , C22C27/04 , C23C14/021 , C23C14/14 , C23C14/165 , C23C14/3435
摘要: A method for preparing a high-hardness anti-bacterial PVD film by deposition of a first anti-bacterial film layer on a workpiece with W—Ti alloy material, wherein W has high hardness and an extremely strong anti-bacterial property, and the combination of Ti and W can facilitate adhesion during the deposition of the anti-bacterial film, thus enhancing the PVD film effect; a second anti-bacterial film layer deposited on the W—Ti anti-bacterial film is W—Ti—Ag, and the addition of nano-silver in the second anti-bacterial film layer can enhance the anti-bacterial effect, and the high hardness of W can protect nano-silver; because of the anti-bacterial property of W itself, only a small amount of nano-silver needs to be added in the outermost layer, and as the price of W is lower than nano-silver in the market, the technical solution can lower the production cost of anti-bacterial film.
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公开(公告)号:US20180105947A1
公开(公告)日:2018-04-19
申请号:US15348477
申请日:2016-11-10
申请人: Fook Chi Mak , Sal Chi Mak
发明人: Fook Chi Mak , Sal Chi Mak
CPC分类号: C25D11/243 , C23F3/03 , C25D11/08 , C25D11/16 , C25D11/246
摘要: A method for preparing an anti-bacterial anodic oxide film on the surface of aluminum materials, comprising pretreatment, polishing, anodic oxidation, dyeing and sealing, wherein the surface of polished aluminum materials is smooth but has undulating waves and holes; in the dyeing after oxidation, a nano-sized dye is filled in the undulating waves and holes on the surface of aluminum materials, so if nano-silver is uniformly mixed in the dye in the process, the dye on the surface of aluminum materials will contain nano-silver finally and it will protect nano-silver from wearing during use; the dye-filled waves on the surface of aluminum materials are sealed via a sealing process finally, i.e., the dye is sealed in the surface of aluminum materials; at last, the surface of aluminum materials can be turned into desired colored patterns according to actual needs, and the nano-silver provides the anodic oxide film with anti-bacterial effect.
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公开(公告)号:US20070259876A1
公开(公告)日:2007-11-08
申请号:US11789832
申请日:2007-04-25
申请人: John Doukas , Chi Mak , Elena Dneprovskaia , Glenn Noronha
发明人: John Doukas , Chi Mak , Elena Dneprovskaia , Glenn Noronha
IPC分类号: A61K31/525 , C07D475/04
CPC分类号: C07D475/08
摘要: Compositions and methods and are provided for treating disorders associated with compromised vasculostasis. Invention methods and compositions are useful for treating a variety of disorders including for example, stroke, myocardial infarction, cancer, ischemia/reperfusion injury, autoimmune diseases such as rheumatoid arthritis, eye diseases such as uveitis, retinopathies or macular degeneration, macular edema or other vitreoretinal diseases, inflammatory diseases such as autoimmune diseases, vascular leakage syndrome, edema, or diseases involving leukocyte activation, transplant rejection, respiratory diseases such as asthma, adult or acute respiratory distress syndrome (ARDS), chronic obstructive pulmonary disease, and the like.
摘要翻译: 组合物和方法,用于治疗与受损的血管淤滞相关的疾病。 本发明的方法和组合物可用于治疗各种疾病,包括例如中风,心肌梗死,癌症,缺血/再灌注损伤,自身免疫疾病如类风湿性关节炎,眼睛疾病如葡萄膜炎,视网膜病变或黄斑变性,黄斑水肿或其他 玻璃体视网膜疾病,诸如自身免疫性疾病,血管渗漏综合征,水肿或涉及白细胞激活的疾病,移植排斥,呼吸系统疾病如哮喘,成人或急性呼吸窘迫综合征(ARDS),慢性阻塞性肺疾病等的炎性疾病。
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公开(公告)号:US20210198782A1
公开(公告)日:2021-07-01
申请号:US16903834
申请日:2020-06-17
申请人: Fook Chi MAK
发明人: Fook Chi MAK
IPC分类号: C23C14/06 , A01N25/34 , A01N59/00 , C23C14/00 , C23C14/02 , C23C14/50 , C23C14/24 , C23C28/04
摘要: The present disclosure discloses a method for preparing a bactericidal film having a silicon nitride binding layer on silicone. The whole process does not need high temperature, the film layers are plated without damaging the silicone. A binding film layer is plated using a silicon target and nitrogen, and a carrier layer is plated using the silicon target and acetylene gas. A silver target is initiated to allow silver ions to be uniformly distributed to form a bactericidal film layer. The silver target is kept sputtering to enable the silver ions to be uniformly distributed on the bactericidal layer, thus forming a composite layer with prominent bactericidal and antimould effects. The present disclosure protects a furnace from being damaged by avoiding the introduction of oxygen during production and prevents the generation of silver oxide caused by the residual oxygen in the furnace during the silver target's sputtering.
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公开(公告)号:US20210180177A1
公开(公告)日:2021-06-17
申请号:US16903870
申请日:2020-06-17
申请人: Fook Chi Mak
发明人: Fook Chi Mak
摘要: A method for preparing a bactericidal film having a silicon nitride binding layer on plastic, wherein the whole process does not need high temperature, and the film layers are plated without damaging the plastic. A binding film layer is plated using a silicon target and nitrogen, and a carrier layer is plated using acetylene gas. A silver target is initiated to allow silver ions to be uniformly distributed to form a bactericidal film layer. The workpiece is hung on the hanging rack during the plating process, which allows the rotation and revolution of the workpiece to be simultaneously achieved, thus realizing a uniform plating during the target's sputtering while avoiding damage to the workpiece due to local high temperature. The present disclosure remains the appearance and various properties of plastic, achieves an ideal bactericidal effect, a convenient preparation and a low investment of equipment, and has a wide application range.
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公开(公告)号:US20070191405A1
公开(公告)日:2007-08-16
申请号:US11588638
申请日:2006-10-26
申请人: Glenn Noronha , Chi Mak , Jianguo Cao , Joel Renick , Andrew McPherson , Binqi Zeng , Ved Pathak , Daniel Lohse , John Hood , Richard Soll
发明人: Glenn Noronha , Chi Mak , Jianguo Cao , Joel Renick , Andrew McPherson , Binqi Zeng , Ved Pathak , Daniel Lohse , John Hood , Richard Soll
IPC分类号: A61K31/506 , C07D403/02 , C07D407/02
CPC分类号: C07D239/48 , C07D239/42 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12
摘要: The invention provides biaryl meta-pyrimidine compounds having the general structure (A). The pyrimidine compounds of the invention are capable of inhibiting kinases, such as members of the Jak kinase family, and various other specific receptor and non-receptor kinases.
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公开(公告)号:US20060254220A1
公开(公告)日:2006-11-16
申请号:US11487903
申请日:2006-07-17
申请人: Justin Patterson , Salvatore Siano , Chi Mak , Heather Jones , Francis Marino , Dave Bossa , Yigal Offir
发明人: Justin Patterson , Salvatore Siano , Chi Mak , Heather Jones , Francis Marino , Dave Bossa , Yigal Offir
IPC分类号: B65B31/00
CPC分类号: B65B31/046 , B65B31/06 , B65B51/146
摘要: A system for evacuating containers. The system includes a base housing defining a recess having a vacuum inlet port in communication with a vacuum source. An inner door is hinged to the base housing and is sized to cover the recess when in a closed position, and an outer door having a sealing member is hinged to close over the inner door. A vacuum nozzle extends at least partially between the inner and outer doors and is in communication with the recess. The inner and outer doors cooperate to retain a flexible container therebetween and around the nozzle so that the nozzle is positioned for fluid communication with an inside of the container. A removable drip pan is positioned to retain fluids drawn by the nozzle.
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公开(公告)号:US20060247250A1
公开(公告)日:2006-11-02
申请号:US11377234
申请日:2006-03-15
申请人: Jianguo Cao , Richard Soll , Glenn Noronha , Kathy Barrett , Colleen Gritzen , John Hood , Chi Mak , Andrew McPherson , Ved Pathak , Joel Renick , Ute Splittgerber , Binqi Zeng
发明人: Jianguo Cao , Richard Soll , Glenn Noronha , Kathy Barrett , Colleen Gritzen , John Hood , Chi Mak , Andrew McPherson , Ved Pathak , Joel Renick , Ute Splittgerber , Binqi Zeng
IPC分类号: A61K31/506 , C07D403/14 , C07D403/02
CPC分类号: C07D239/48 , C07D239/49 , C07D401/12 , C07D417/12
摘要: The invention provides pyrimidine compounds having formula A. The pyrimidine compounds of the invention are capable of inhibiting kinases, such as members of the Src kinase family, and various other specific receptor and non-receptor kinases.
摘要翻译: 本发明提供具有式A的嘧啶化合物。本发明的嘧啶化合物能够抑制激酶,例如Src激酶家族的成员和各种其它特异性受体和非受体激酶。
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公开(公告)号:US20050245524A1
公开(公告)日:2005-11-03
申请号:US11102405
申请日:2005-04-07
申请人: Glenn Noronha , Kathy Barrett , Jianguo Cao , Colleen Gritzen , Xianchang Gong , John Hood , Chi Mak , Andrew McPherson , Ved Pathak , Joel Renick , Richard Soll , Ute Splittgerber , Wolfgang Wrasdilo , Ningning Zhao , Elena Dneprovskaia
发明人: Glenn Noronha , Kathy Barrett , Jianguo Cao , Colleen Gritzen , Xianchang Gong , John Hood , Chi Mak , Andrew McPherson , Ved Pathak , Joel Renick , Richard Soll , Ute Splittgerber , Wolfgang Wrasdilo , Ningning Zhao , Elena Dneprovskaia
CPC分类号: C07D253/08 , C07D403/04 , C07D403/12 , C07D413/04
摘要: The invention provides benzotriazine compounds having formula (I). The benzotriazine compounds of the invention are capable of inhibiting kinases, such members of the Src kinase family, and various other specific receptor and non-receptor kinases.
摘要翻译: 本发明提供具有式(I)的苯并三嗪化合物。 本发明的苯并三嗪化合物能够抑制激酶,Src激酶家族的成员和各种其它特异性受体和非受体激酶。
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公开(公告)号:US20050218030A1
公开(公告)日:2005-10-06
申请号:US11089004
申请日:2005-03-24
申请人: Chi Mak
发明人: Chi Mak
IPC分类号: B65B11/50 , B65B11/58 , B65B23/00 , B65B31/00 , B65B31/06 , B65B55/20 , B65D25/10 , B65D81/05 , B65D81/07 , B65D81/107 , B65D85/30
CPC分类号: B65B11/50 , B65B11/58 , B65B23/00 , B65B31/06 , B65B55/20 , B65D81/052 , B65D81/075 , B65D81/1075
摘要: The invention basically includes an outer layer made of flexible sheets of synthetic resinous or impervious materials, and/or rigid and/or semi-rigid materials while the wrapping of each article may be held inside the packaging system by flexible linkages. The portion of the wrapping that is not directly wrapping the article should be considered as the flange of the wrapping which will become the “linkage” in the glossary of this invention. The wrapping may be designed with openings for the protruded, fragile or sharp members of the article to avoid damage to these parts. The wrapping may be made as a closed cell and a negative pressure (vacuum) may be applied to securely grasp the article. For those articles that are not suited for tight wrap, certain fluids (e.g., air) may be provided to the inside of the sealed wrapping to counteract the inflation pressure at the outside of the wrapping.
摘要翻译: 本发明基本上包括由合成树脂或不渗透材料的柔性片材制成的外层,和/或刚性和/或半刚性材料,而每个制品的包装可通过柔性连接件保持在包装系统内。 不直接包裹物品的包装部分应视为包装的法兰,这将成为本发明术语表中的“连接”。 可以将包装设计成具有用于制品的突出,易碎或锋利构件的开口,以避免损坏这些部件。 包装可以制成闭孔,并且可以施加负压(真空)以牢固地抓住物品。 对于不适合紧密包裹的那些制品,可以将某些流体(例如空气)提供到密封的包装的内部,以抵消包装外部的充气压力。
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