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    METHODS FOR IDENTIFYING AGENTS WHICH ALTER HISTONE PROTEIN ACETYLATION, DECREASE AGING OR INCREASE LIFESPAN
    4.
    发明申请
    METHODS FOR IDENTIFYING AGENTS WHICH ALTER HISTONE PROTEIN ACETYLATION, DECREASE AGING OR INCREASE LIFESPAN 有权
    用于鉴定肝细胞蛋白质乙酰化，降解衰老或增加生殖激素的药剂的方法

    公开(公告)号：US20090155834A1

    公开(公告)日：2009-06-18

    申请号：US12209847

    申请日：2008-09-12

    申请人： LEONARD GUARENTE ,  SHIN-ICHIRO IMAI ,  CHRISTOPHER ARMSTRONG

    发明人： LEONARD GUARENTE ,  SHIN-ICHIRO IMAI ,  CHRISTOPHER ARMSTRONG

    IPC分类号： C12Q1/02 ,  C12N9/00

    CPC分类号： G01N33/66 ,  A61K38/1709 ,  C12Q1/48 ,  G01N2500/00 ,  Y02A50/473 ,  A61K2300/00

    摘要： Methods of identifying agents which alter the NAD-dependent acetylation status and mono-ADP-ribosylation of nuclear proteins are disclosed. The methods further include identifying agents which alter the life span or aging of a cell or an organism by determining the level of NAD-dependent acetylation and/or ADP ribosylation of a nuclear protein. The invention also relates to a mammalian Sir2 protein which acetylates or deacetylates nuclear proteins in a NAD-dependent manner and has mono-ADP-ribosyltransferase activity. Host cells producing the Sir2 protein and antibodies to the Sir2 protein are also provided.

    摘要翻译： 公开了鉴定改变核蛋白的NAD依赖性乙酰化状态和单ADP-核糖基化的试剂的方法。 所述方法还包括通过确定核蛋白的NAD依赖性乙酰化和/或ADP核糖基化的水平来鉴定改变细胞或生物体的寿命或衰老的试剂。 本发明还涉及哺乳动物Sir2蛋白，其以NAD依赖性方式乙酰化或脱乙酰化核蛋白并具有单ADP-核糖基转移酶活性。 还提供了产生Sir2蛋白的宿主细胞和Sir2蛋白的抗体。

    Device Independent Data Streaming
    8.
    发明申请
    Device Independent Data Streaming 审中-公开
    设备独立数据流

    公开(公告)号：US20070299982A1

    公开(公告)日：2007-12-27

    申请号：US11570274

    申请日：2005-06-08

    申请人： Christopher Armstrong ,  Eamonn Roarke

    发明人： Christopher Armstrong ,  Eamonn Roarke

    IPC分类号： G06F15/16

    CPC分类号： H04L65/4092 ,  H04L29/06027 ,  H04L67/327 ,  H04L67/34 ,  H04L69/329

    摘要： A system and method are provided for controlling data distribution in a network (108, 109). The network has data-generating and data-receiving devices (101, 102, 103, 105, 106, 111, 112, 113, 116, 117, 118, 206). The system includes memory means (209), processing means (203), networking means (212), at least one input controller (404) and at least one output controller (404). The memory means (209) stores instructions (402) which configure said processing means (208) to identify data-generating devices (101, 102, 206, 111, 112 113) and data-receiving devices (103, 105, 106, 107, 116, 117, 118) in said network. The identified devices (102, 103, 105, 106, 111, 112, 113, 116, 117, 118, 206) are initialised across said network by way of said input controller (404) and one output controller (404). Input data (405, 406) is controlled by said input controller (404). Output data (407, 408) is controlled by said output controller (404). Control is performed selectively according to user input (409).

    摘要翻译： 提供了一种用于控制网络（108,109）中的数据分发的系统和方法。 网络具有数据生成和数据接收设备（101,102,103,105,106,111,112,113,116,117,118,206）。 该系统包括存储装置（209），处理装置（203），网络装置（212），至少一个输入控制器（404）和至少一个输出控制器（404）。 存储装置（209）存储指令（402），其配置所述处理装置（208）以识别数据生成装置（101,102,206,111,112,113）和数据接收装置（103,105,106,107 ，116,117,118）。 所识别的设备（102,103,105,106,111,112,113,116,117,118,206）通过所述输入控制器（404）和一个输出控制器（404）通过所述网络初始化。 输入数据（405,406）由所述输入控制器（404）控制。 输出数据（407,408）由所述输出控制器（404）控制。 根据用户输入选择性地进行控制（409）。

    Apparatus for washing and laundering garments
    10.
    发明授权
    Apparatus for washing and laundering garments 失效
    清洗和洗衣服装的设备

    公开(公告)号：US3942340A

    公开(公告)日：1976-03-09

    申请号：US486103

    申请日：1974-07-05

    申请人： Christopher Armstrong Kirkby

    发明人： Christopher Armstrong Kirkby

    IPC分类号： D06F31/00

    CPC分类号： D06F31/00

    摘要： A machine for washing and laundering garments on hangers comprises a substantially vertical conveyor for lifting a garment on a hanger, transferring the hanger to a stationary conveyor along which it travels at two speeds through spraying chambers and dripping chambers, a transfer pulley to transfer the hanger from the stationary conveyor to an endless conveyor, further spraying chambers, and dripping chambers through which the hanger passes to a drying chamber to dry the garment on the hanger or set a coating thereon.

    摘要翻译： 用于衣架上衣物洗涤和洗涤的机器包括一个基本垂直的输送机，用于将衣服提升在衣架上，将衣架转移到固定式输送机上，两个速度通过喷雾室和滴水室传送，固定式传送带，转移滑轮 从固定输送机到环形输送机，进一步喷射室和滴水室，悬挂架通过该室移动到干燥室，以将衣服干燥或在其上设置涂层。