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公开(公告)号:US20160082156A1
公开(公告)日:2016-03-24
申请号:US14839786
申请日:2015-08-28
申请人: Christopher G. WILSON , Eric J. Vanderploeg , Howard Seeherman , Zachary Decker , Eric Schmidt , Bethany Moore , Alexander Heubeck
发明人: Christopher G. WILSON , Eric J. Vanderploeg , Howard Seeherman , Zachary Decker , Eric Schmidt , Bethany Moore , Alexander Heubeck
CPC分类号: A61L27/44 , A61F2/28 , A61F2002/2817 , A61F2002/2835 , A61L27/46 , A61L27/54 , A61L27/56 , A61L2300/414 , A61L2400/06 , A61L2430/02 , A61L2430/24
摘要: Systems and methods for preparing osteoinductive synthetic bone grafts are provided in which a porous ceramic granule is loaded with an osteoinductive material, and then placed in contact with a biocompatible matrix material.
摘要翻译: 提供用于制备骨诱导性合成骨移植物的系统和方法,其中多孔陶瓷颗粒装载有骨诱导材料,然后与生物相容性基质材料接触。
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公开(公告)号:US20170209623A1
公开(公告)日:2017-07-27
申请号:US15339834
申请日:2016-10-31
申请人: Eric Vanderploeg , Howard Seeherman , Christopher G. Wilson , John Wozney , Christopher Todd Brown
发明人: Eric Vanderploeg , Howard Seeherman , Christopher G. Wilson , John Wozney , Christopher Todd Brown
CPC分类号: A61L27/56 , A61L24/0015 , A61L24/0036 , A61L24/0073 , A61L27/10 , A61L27/24 , A61L27/46 , A61L27/54 , A61L2300/252 , A61L2300/414 , A61L2430/02
摘要: Systems and methods for preparing osteoinductive synthetic bone grafts are provided in which a porous ceramic granule, which may be incorporated within a biocompatible matrix material, is loaded with an osteoinductive agent. Loading of granules is facilitated in some cases by the use of low-pH buffers and pre-treatments.
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