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公开(公告)号:US08580253B2
公开(公告)日:2013-11-12
申请号:US12513830
申请日:2007-11-06
申请人: Ifat Rubin-Bejerano , Gerald R. Fink , Claudia Abeijon , Danial S. Kohane , Jason E. Fuller , Robert S. Langer
发明人: Ifat Rubin-Bejerano , Gerald R. Fink , Claudia Abeijon , Danial S. Kohane , Jason E. Fuller , Robert S. Langer
IPC分类号: A61K39/395 , A61K38/00
CPC分类号: A61K31/716 , A61K8/73 , A61K36/09 , A61K45/06 , A61Q19/00 , A61K2300/00
摘要: This invention is directed to β-1-6-glucans, compositions and devices comprising the same, and methods of use thereof in modulating immune responses. The β-1-6-glucans of certain embodiments of the invention are enriched for O-acetylated groups and/or conjugated to a solid support or linked to a targeting moiety.
摘要翻译: 本发明涉及β-1-6-葡聚糖,包含其的组合物和装置及其在调节免疫应答中的用途。 本发明的某些实施方案的β-1-6-葡聚糖富含O-乙酰化基团和/或与固体支持物缀合或连接至靶向部分。
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公开(公告)号:US20110045049A1
公开(公告)日:2011-02-24
申请号:US12513830
申请日:2007-11-06
申请人: Ifat Rubin-Bejerano , Gerald R. Fink , Claudia Abeijon , Danial S. Kohane , Jason E. Fuller , Robert S. Langer
发明人: Ifat Rubin-Bejerano , Gerald R. Fink , Claudia Abeijon , Danial S. Kohane , Jason E. Fuller , Robert S. Langer
IPC分类号: A61F2/00 , A61K9/00 , A61F6/08 , A61K39/395 , A61K39/12 , A61K39/02 , A61K39/002 , A61K39/35 , A61K39/00 , C12N5/071 , A61K38/02 , A61K31/716 , C08B37/00 , A61P35/00 , A61P37/02 , A61P37/04 , A61P31/12 , A61P31/04 , A61P33/10 , A61P33/00 , A61P37/06
CPC分类号: A61K31/716 , A61K8/73 , A61K36/09 , A61K45/06 , A61Q19/00 , A61K2300/00
摘要: This invention is directed to β-1-6-glucans, compositions and devices comprising the same, and methods of use thereof in modulating immune responses. The β-1-6-glucans of certain embodiments of the invention are enriched for O-acetylated groups and/or conjugated to a solid support or linked to a targeting moiety.
摘要翻译: 本发明涉及β-葡聚糖,包含其的组合物和装置及其在调节免疫应答中的用途。 本发明某些实施方案的β-葡聚糖富含O-乙酰化基团和/或与固体支持物缀合或与靶向部分连接。
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