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公开(公告)号:US20110045049A1
公开(公告)日:2011-02-24
申请号:US12513830
申请日:2007-11-06
申请人: Ifat Rubin-Bejerano , Gerald R. Fink , Claudia Abeijon , Danial S. Kohane , Jason E. Fuller , Robert S. Langer
发明人: Ifat Rubin-Bejerano , Gerald R. Fink , Claudia Abeijon , Danial S. Kohane , Jason E. Fuller , Robert S. Langer
IPC分类号: A61F2/00 , A61K9/00 , A61F6/08 , A61K39/395 , A61K39/12 , A61K39/02 , A61K39/002 , A61K39/35 , A61K39/00 , C12N5/071 , A61K38/02 , A61K31/716 , C08B37/00 , A61P35/00 , A61P37/02 , A61P37/04 , A61P31/12 , A61P31/04 , A61P33/10 , A61P33/00 , A61P37/06
CPC分类号: A61K31/716 , A61K8/73 , A61K36/09 , A61K45/06 , A61Q19/00 , A61K2300/00
摘要: This invention is directed to β-1-6-glucans, compositions and devices comprising the same, and methods of use thereof in modulating immune responses. The β-1-6-glucans of certain embodiments of the invention are enriched for O-acetylated groups and/or conjugated to a solid support or linked to a targeting moiety.
摘要翻译: 本发明涉及β-葡聚糖,包含其的组合物和装置及其在调节免疫应答中的用途。 本发明某些实施方案的β-葡聚糖富含O-乙酰化基团和/或与固体支持物缀合或与靶向部分连接。
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公开(公告)号:US08580253B2
公开(公告)日:2013-11-12
申请号:US12513830
申请日:2007-11-06
申请人: Ifat Rubin-Bejerano , Gerald R. Fink , Claudia Abeijon , Danial S. Kohane , Jason E. Fuller , Robert S. Langer
发明人: Ifat Rubin-Bejerano , Gerald R. Fink , Claudia Abeijon , Danial S. Kohane , Jason E. Fuller , Robert S. Langer
IPC分类号: A61K39/395 , A61K38/00
CPC分类号: A61K31/716 , A61K8/73 , A61K36/09 , A61K45/06 , A61Q19/00 , A61K2300/00
摘要: This invention is directed to β-1-6-glucans, compositions and devices comprising the same, and methods of use thereof in modulating immune responses. The β-1-6-glucans of certain embodiments of the invention are enriched for O-acetylated groups and/or conjugated to a solid support or linked to a targeting moiety.
摘要翻译: 本发明涉及β-1-6-葡聚糖,包含其的组合物和装置及其在调节免疫应答中的用途。 本发明的某些实施方案的β-1-6-葡聚糖富含O-乙酰化基团和/或与固体支持物缀合或连接至靶向部分。
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公开(公告)号:US20100215708A1
公开(公告)日:2010-08-26
申请号:US12306794
申请日:2007-06-28
申请人: Andreas Zumbuehl , Danial S. Kohane , Lino Da Silva Ferreira , Robert S. Langer , Gerald R. Fink
发明人: Andreas Zumbuehl , Danial S. Kohane , Lino Da Silva Ferreira , Robert S. Langer , Gerald R. Fink
IPC分类号: A61F2/00 , A61K31/7088 , A61K31/713 , A61K31/7048 , A61K9/16 , A61K9/70 , A61P31/00 , A61M25/00 , A61M27/00 , A61M16/04
CPC分类号: A61L27/54 , A61L27/34 , A61L2300/404 , A61L2300/602
摘要: This invention is directed to substrates, materials and devices coated with a gel, foam, film, particle or composition comprising a polymei solvent and effector compounds attached thereto, processes of producing the same, and methods of use thereof, of in, inter-alia, biological applications, including preventing infection and the treatment of various diseases.
摘要翻译: 本发明涉及涂覆有凝胶,泡沫,膜,颗粒或组合物的基材,材料和装置,其包含多聚酯溶剂和附着于其上的效应化合物,其制备方法及其使用方法, ,生物应用,包括预防感染和各种疾病的治疗。
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