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公开(公告)号：US20140084272A1
公开(公告)日：2014-03-27
申请号：US14009069
申请日：2012-03-21
IPC分类号： H01L21/306 , H01L51/00 , H01L29/02
CPC分类号： H01L21/306 , G03F7/2022 , H01L29/02 , H01L51/0001 , H01L51/0003 , H01L51/0018 , H01L51/0096 , H01L51/5212 , H01L2251/5361 , H01L2251/5392 , Y02E10/549
摘要： This invention generally relates to planarisation of a surface of a substrate. In an embodiment of planarising a surface region of a substrate, the substrate having a body on a portion of said surface region, the method comprises: modifying the wetability of a surface of said body with respect to a liquid planariser composition by providing a surface modifying layer such as a self-assembled monolayer thereon; and then depositing the liquid planariser composition on said substrate and said body such that the planariser composition wets said surface region, wherein said surface modifying layer determines a contact angle of said liquid planariser composition to said surface of said body such that the deposited liquid planariser composition is repelled from said surface of said body.
摘要翻译： 本发明一般涉及基板表面的平面化。 在平面化衬底的表面区域的一个实施例中，衬底在所述表面区域的一部分上具有主体，该方法包括：通过提供表面修饰来改变所述主体的表面相对于液体平面剂组合物的可润湿性 层，例如其上的自组装单层; 然后将液体平面剂组合物沉积在所述基材和所述体上，使得平面剂组合物润湿所述表面区域，其中所述表面改性层确定所述液体平面剂组合物与所述体的所述表面的接触角，使得沉积的液体平面剂组合物 从所述身体的所述表面排出。
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公开(公告)号：US20100105034A1
公开(公告)日：2010-04-29
申请号：US12302691
申请日：2007-05-30
申请人： Michael L. Hutton , Matthew Colin Baker , Jennifer Mae Gass , Rosa Rademakers , Jason Eriksen , Stuart M. Pickering-Brown , Ian Reid Alexander Mackenzie , Howard Feldman , Samir Kumar-Singh , Christine Van Broeckhoven , Marc Cruts
发明人： Michael L. Hutton , Matthew Colin Baker , Jennifer Mae Gass , Rosa Rademakers , Jason Eriksen , Stuart M. Pickering-Brown , Ian Reid Alexander Mackenzie , Howard Feldman , Samir Kumar-Singh , Christine Van Broeckhoven , Marc Cruts
CPC分类号： A61K48/005 , C07K14/435 , C12Q1/6809 , C12Q1/6883 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , C12Q2600/16 , C12Q2600/172
摘要： This document relates to methods and materials for detecting mutations that can be linked to dementia. For example, methods and materials for detecting one or more mutations within PGRN nucleic acid are provided. This document also provides methods and materials for detecting the level of progranulin expression. In addition, this document relates to methods and materials for treating mammals having a neurodegenerative disorder (e.g., dementia). For example, methods and materials for increasing PGRN polypeptide levels in mammals are provided, as are methods and materials for identifying agents that can be used to increase PGRN polypeptide levels in mammals.
摘要翻译： 本文件涉及用于检测可与痴呆相关的突变的方法和材料。 例如，提供了用于检测PGRN核酸内的一个或多个突变的方法和材料。 本文件还提供了检测颗粒体蛋白前体表达水平的方法和材料。 此外，本文件涉及用于治疗具有神经变性疾病（例如痴呆）的哺乳动物的方法和材料。 例如，提供用于增加哺乳动物中PGRN多肽水平的方法和材料，以及用于鉴定可用于增加哺乳动物中PGRN多肽水平的试剂的方法和材料。
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公开(公告)号：US11300012B2
公开(公告)日：2022-04-12
申请号：US16694767
申请日：2019-11-25
摘要： A power system is configured to generate mechanical energy from supercritical carbon dioxide in a closed loop. The power system includes a compressor that yields a high pressure supercritical carbon dioxide. A heat exchanger is operatively connected to the compressor and yields a high enthalpy supercritical carbon dioxide. A rotary engine is operatively connected to the heat exchanger and configured to convert thermal energy from the high enthalpy supercritical carbon dioxide into mechanical energy and an output supercritical carbon dioxide. A pressure differential orifice is operatively coupled to the rotary engine and to the heat exchanger and configured to decrease the temperature and the pressure of the output supercritical carbon dioxide resulting in a low pressure low temperature supercritical carbon dioxide. The low pressure low temperature supercritical carbon dioxide is heated in the heat exchanger and the renters the compressor completing the closed loop.
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公开(公告)号：US20200165940A1
公开(公告)日：2020-05-28
申请号：US16694767
申请日：2019-11-25
摘要： A power system is configured to generate mechanical energy from supercritical carbon dioxide in a closed loop. The power system includes a compressor that yields a high pressure supercritical carbon dioxide. A heat exchanger is operatively connected to the compressor and yields a high enthalpy supercritical carbon dioxide. A rotary engine is operatively connected to the heat exchanger and configured to convert thermal energy from the high enthalpy supercritical carbon dioxide into mechanical energy and an output supercritical carbon dioxide. A pressure differential orifice is operatively coupled to the rotary engine and to the heat exchanger and configured to decrease the temperature and the pressure of the output supercritical carbon dioxide resulting in a low pressure low temperature supercritical carbon dioxide. The low pressure low temperature supercritical carbon dioxide is heated in the heat exchanger and the renters the compressor completing the closed loop.
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公开(公告)号：US10081780B1
公开(公告)日：2018-09-25
申请号：US14952253
申请日：2015-11-25
CPC分类号： C11B9/025 , B01D11/0203 , B01D11/0207 , B01D11/028
摘要： A system can be used for extracting essential oils from plant matter. The system includes an extraction vessel that is configured to hold the plant matter from which the essential oil is extracted. A separation vessel is connected to the extraction vessel and configured to separate the essential oil from the plant matter. A compressor is connected to the extraction vessel and the separation vessel with a fluid system and configured to use super critical carbon dioxide to push the essential oil from the extraction vessel to the separation vessel separating the essential oil from the plant matter. A heat exchanger is attached to the fluid system and configured to cool the carbon dioxide released from the compressor. A control system is connected to the compressor.
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公开(公告)号：US09054042B2
公开(公告)日：2015-06-09
申请号：US14009069
申请日：2012-03-21
CPC分类号： H01L21/306 , G03F7/2022 , H01L29/02 , H01L51/0001 , H01L51/0003 , H01L51/0018 , H01L51/0096 , H01L51/5212 , H01L2251/5361 , H01L2251/5392 , Y02E10/549
摘要： This invention generally relates to planarisation of a surface of a substrate. In an embodiment of planarising a surface region of a substrate, the substrate having a body on a portion of said surface region, the method comprises: modifying the wetability of a surface of said body with respect to a liquid planariser composition by providing a surface modifying layer such as a self-assembled monolayer thereon; and then depositing the liquid planariser composition on said substrate and said body such that the planariser composition wets said surface region, wherein said surface modifying layer determines a contact angle of said liquid planariser composition to said surface of said body such that the deposited liquid planariser composition is repelled from said surface of said body.
摘要翻译： 本发明一般涉及基板表面的平面化。 在平面化衬底的表面区域的一个实施例中，衬底在所述表面区域的一部分上具有主体，该方法包括：通过提供表面修饰来改变所述主体的表面相对于液体平面剂组合物的可润湿性 层，例如其上的自组装单层; 然后将液体平面剂组合物沉积在所述基材和所述体上，使得平面剂组合物润湿所述表面区域，其中所述表面改性层确定所述液体平面剂组合物与所述体的所述表面的接触角，使得沉积的液体平面剂组合物 从所述身体的所述表面排出。
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