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公开(公告)号:US08282940B2
公开(公告)日:2012-10-09
申请号:US12384476
申请日:2009-04-03
IPC分类号: A61K39/29 , A61K39/00 , A61K39/12 , A61K39/02 , A61K39/112 , A61K39/002
CPC分类号: A61K39/39 , A61K39/385 , A61K2039/525 , A61K2039/5256 , A61K2039/5258 , A61K2039/6075 , A61K2039/64 , C07K14/005 , C07K2319/00 , C12N2770/24222 , C12N2770/26023 , Y02A50/484
摘要: The present invention relates to an immunogen-carrier having immunopotentiating or adjuvant properties. More particularly, the immunogen-carrier is a virus-like particle (VLP) from the family of potexvirus, and most particularly the papaya mosaic virus. The VLP produced by recombinant techniques is in fusion with one of its own proteins a protein immunogen. The above VLP and a protein or a protein extract from a viral, bacterial or parasital pathogen may be used as a vaccine.
摘要翻译: 本发明涉及具有免疫增强或佐剂性质的免疫原载体。 更具体地,免疫原载体是来自虫病毒病毒的病毒样颗粒(VLP),最特别是木瓜花叶病毒。 通过重组技术产生的VLP与其自身蛋白质之一融合蛋白免疫原。 上述VLP和来自病毒,细菌或寄生虫病原体的蛋白质或蛋白质提取物可以用作疫苗。