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公开(公告)号：US20160151299A1
公开(公告)日：2016-06-02
申请号：US15014655
申请日：2016-02-03
IPC分类号： A61K9/70 , A61K31/473 , A61K45/06 , A61K31/4045 , A61K31/4985 , A61J7/00 , A61K31/506 , A61K31/428 , A61K31/381 , B29C39/18 , B65D65/38 , A61J1/03 , A61K9/00 , A61K31/48
CPC分类号： A61K9/7007 , A61F13/00063 , A61J1/03 , A61J7/0053 , A61K9/006 , A61K9/209 , A61K31/381 , A61K31/4045 , A61K31/428 , A61K31/4415 , A61K31/473 , A61K31/48 , A61K31/485 , A61K31/4985 , A61K31/506 , A61K45/06 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/183 , A61K47/22 , A61K47/36 , A61K47/38 , B29C39/18 , B29C39/38 , B29C43/305 , B29C43/52 , B29C65/70 , B29C66/45 , B29K2001/00 , B29L2007/008 , B29L2009/00 , B29L2031/753 , B29L2031/755 , B65D65/38 , A61K2300/00
摘要： The invention features sublingual film formulations of dopamine agonists and methods of treating Parkinson's disease, tremors, restless leg syndrome, sexual dysfunction, and depressive disorders therewith.
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公开(公告)号：US20160338972A1
公开(公告)日：2016-11-24
申请号：US15225992
申请日：2016-08-02
IPC分类号： A61K9/70 , A61K31/473 , A61K47/38 , A61K47/22 , A61K47/14 , A61K47/10 , A61K47/36 , A61K47/02 , A61K47/18 , A61K47/12 , A61K31/4045 , A61K31/4985 , A61K31/48 , A61K31/506 , A61K31/428 , A61K45/06 , B29C39/18 , B29C39/38 , B29C43/30 , B29C43/52 , B29C65/70 , B29C65/00 , B65D65/38 , A61J1/03 , A61K9/00
CPC分类号： A61K9/7007 , A61F13/00063 , A61J1/03 , A61J7/0053 , A61K9/006 , A61K9/209 , A61K31/381 , A61K31/4045 , A61K31/428 , A61K31/4415 , A61K31/473 , A61K31/48 , A61K31/485 , A61K31/4985 , A61K31/506 , A61K45/06 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/183 , A61K47/22 , A61K47/36 , A61K47/38 , B29C39/18 , B29C39/38 , B29C43/305 , B29C43/52 , B29C65/70 , B29C66/45 , B29K2001/00 , B29L2007/008 , B29L2009/00 , B29L2031/753 , B29L2031/755 , B65D65/38 , A61K2300/00
摘要： The invention features sublingual film formulations of dopamine agonists and methods of treating Parkinson's disease, tremors, restless leg syndrome, sexual dysfunction, and depressive disorders therewith.
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公开(公告)号：US09427412B2
公开(公告)日：2016-08-30
申请号：US15014655
申请日：2016-02-03
IPC分类号： A61K31/435 , A61K9/70 , A61P25/16 , A61K47/02 , A61K31/4415 , A61F13/00 , A61K9/00 , A61K47/14 , A61K47/38 , A61K31/4045 , A61K31/485 , A61K31/473 , A61K45/06 , A61K31/381 , A61K31/428 , A61K31/48 , A61K31/4985 , A61K31/506 , A61J1/03 , A61J7/00 , B29C39/18 , B65D65/38 , A61K9/24 , B29K1/00 , B29L31/00
CPC分类号： A61K9/7007 , A61F13/00063 , A61J1/03 , A61J7/0053 , A61K9/006 , A61K9/209 , A61K31/381 , A61K31/4045 , A61K31/428 , A61K31/4415 , A61K31/473 , A61K31/48 , A61K31/485 , A61K31/4985 , A61K31/506 , A61K45/06 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/183 , A61K47/22 , A61K47/36 , A61K47/38 , B29C39/18 , B29C39/38 , B29C43/305 , B29C43/52 , B29C65/70 , B29C66/45 , B29K2001/00 , B29L2007/008 , B29L2009/00 , B29L2031/753 , B29L2031/755 , B65D65/38 , A61K2300/00
摘要： The invention features sublingual film formulations of dopamine agonists and methods of treating Parkinson's disease, tremors, restless leg syndrome, sexual dysfunction, and depressive disorders therewith.
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公开(公告)号：US20160101101A1
公开(公告)日：2016-04-14
申请号：US14971532
申请日：2015-12-16
IPC分类号： A61K31/485 , A61K9/70 , A61K9/00
CPC分类号： A61K31/485 , A61K9/0056 , A61K9/006 , A61K9/06 , A61K9/2086 , A61K9/7007 , A61K31/473 , A61K47/02 , A61K47/10 , A61K47/183 , Y10T428/2982
摘要： The invention features sublingual formulations of apomorphine and apomorphine prodrugs, and methods of treating Parkinson's disease, sexual dysfunction, and depressive disorders therewith.
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公开(公告)号：US20130225626A1
公开(公告)日：2013-08-29
申请号：US13858638
申请日：2013-04-08
IPC分类号： A61K9/70 , A61K45/06 , A61K31/473
CPC分类号： A61K9/7007 , A61F13/00063 , A61J1/03 , A61J7/0053 , A61K9/006 , A61K9/209 , A61K31/381 , A61K31/4045 , A61K31/428 , A61K31/4415 , A61K31/473 , A61K31/48 , A61K31/485 , A61K31/4985 , A61K31/506 , A61K45/06 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/183 , A61K47/22 , A61K47/36 , A61K47/38 , B29C39/18 , B29C39/38 , B29C43/305 , B29C43/52 , B29C65/70 , B29C66/45 , B29K2001/00 , B29L2007/008 , B29L2009/00 , B29L2031/753 , B29L2031/755 , B65D65/38 , A61K2300/00
摘要： The invention features sublingual film formulations of dopamine agonists and methods of treating Parkinson's disease, tremors, restless leg syndrome, sexual dysfunction, and depressive disorders therewith.
摘要翻译： 本发明具有多巴胺激动剂的舌下膜制剂和治疗帕金森病，震颤，不宁腿综合症，性功能障碍和与此有关的抑郁症的方法。
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公开(公告)号：US09326981B2
公开(公告)日：2016-05-03
申请号：US14684146
申请日：2015-04-10
IPC分类号： A61F13/00 , A61K31/485 , A61K9/70 , A61K31/473 , A61K47/02 , A61K9/00 , A61K9/06 , A61K9/20
CPC分类号： A61K31/485 , A61K9/0056 , A61K9/006 , A61K9/06 , A61K9/2086 , A61K9/7007 , A61K31/473 , A61K47/02 , A61K47/10 , A61K47/183 , Y10T428/2982
摘要： The invention features methods involving the use of sublingual film formulations of apomorphine for treating Parkinson's disease. The methods involve providing the sublingual film formulation and administering the sublingual film formulation sublingually in the mouth of a subject by contacting sublingual mucosal tissue with the film.
摘要翻译： 本发明的特征在于涉及使用阿扑吗啡的舌下膜制剂治疗帕金森病的方法。 所述方法包括提供舌下膜制剂并通过将舌下粘膜组织与膜接触来舌下施用舌下的受试者口腔。
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公开(公告)号：US20160089328A1
公开(公告)日：2016-03-31
申请号：US14963971
申请日：2015-12-09
CPC分类号： A61K31/485 , A61K9/0056 , A61K9/006 , A61K9/06 , A61K9/2086 , A61K9/7007 , A61K31/473 , A61K47/02 , A61K47/10 , A61K47/183 , Y10T428/2982
摘要： The invention features sublingual formulations of apomorphine and apomorphine prodrugs, and methods of treating Parkinson's disease, sexual dysfunction, and depressive disorders therewith.
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公开(公告)号：US20150216859A1
公开(公告)日：2015-08-06
申请号：US14684146
申请日：2015-04-10
IPC分类号： A61K31/485 , A61K9/00 , A61K9/70
CPC分类号： A61K31/485 , A61K9/0056 , A61K9/006 , A61K9/06 , A61K9/2086 , A61K9/7007 , A61K31/473 , A61K47/02 , A61K47/10 , A61K47/183 , Y10T428/2982
摘要： The invention features sublingual formulations of apomorphine and apomorphine prodrugs, and methods of treating Parkinson's disease, sexual dysfunction, and depressive disorders therewith.
摘要翻译： 本发明的特征在于阿扑吗啡和阿朴吗啡前药的舌下制剂，以及治疗帕金森病，性功能障碍和抑郁障碍的方法。
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公开(公告)号：US08846074B2
公开(公告)日：2014-09-30
申请号：US13858638
申请日：2013-04-08
IPC分类号： A61K9/24 , A61K31/4415 , A61K31/485 , A61K9/70 , A61F13/00 , A61K47/02 , A61K9/00 , A61K47/14 , A61K47/38 , A61K31/4045 , A61K31/473 , A61K45/06
CPC分类号： A61K9/7007 , A61F13/00063 , A61J1/03 , A61J7/0053 , A61K9/006 , A61K9/209 , A61K31/381 , A61K31/4045 , A61K31/428 , A61K31/4415 , A61K31/473 , A61K31/48 , A61K31/485 , A61K31/4985 , A61K31/506 , A61K45/06 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/183 , A61K47/22 , A61K47/36 , A61K47/38 , B29C39/18 , B29C39/38 , B29C43/305 , B29C43/52 , B29C65/70 , B29C66/45 , B29K2001/00 , B29L2007/008 , B29L2009/00 , B29L2031/753 , B29L2031/755 , B65D65/38 , A61K2300/00
摘要： The invention features sublingual film formulations of dopamine agonists and methods of treating Parkinson's disease, tremors, restless leg syndrome, sexual dysfunction, and depressive disorders therewith.
摘要翻译： 本发明具有多巴胺激动剂的舌下膜制剂和治疗帕金森病，震颤，不宁腿综合症，性功能障碍和与其抑郁症有关的方法。
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公开(公告)号：US20160095851A1
公开(公告)日：2016-04-07
申请号：US14962806
申请日：2015-12-08
IPC分类号： A61K31/473 , A61K47/10 , A61K47/18 , A61K9/00 , A61K9/70
摘要： The invention features sublingual formulations of apomorphine and apomorphine prodrugs, and methods of treating Parkinson's disease, sexual dysfunction, and depressive disorders therewith.
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