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公开(公告)号:US07371381B2
公开(公告)日:2008-05-13
申请号:US11009443
申请日:2004-12-10
申请人: Wade Aaron , Richard J. Austin , Cynthia L. Hart , Timothy C. Hoey , Paul D. Kassner , Derek E. Piper , Anthony J. Slavin
发明人: Wade Aaron , Richard J. Austin , Cynthia L. Hart , Timothy C. Hoey , Paul D. Kassner , Derek E. Piper , Anthony J. Slavin
IPC分类号: C07K16/28 , A61K39/395
CPC分类号: C07K16/26 , A61K2039/505 , C07K2317/24 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/92
摘要: The present invention provides antibodies that immunospecifically bind to a galanin peptide and compositions comprising said antibodies. The present invention also provides methods for preventing, treating, managing, and/or ameliorating hyperproliferative disorders or a symptom thereof comprising administering to a subject in need thereof one or more antibodies that immunospecifically bind to a galanin peptide. The invention also encompasses methods and compositions for diagnosing, monitoring, and prognosing hyperproliferative disorders. The present invention further relates to articles of manufacture and kits comprising antibodies that immunospecifically bind to a galanin peptide.
摘要翻译: 本发明提供免疫特异性结合甘丙肽肽的抗体和包含所述抗体的组合物。 本发明还提供了预防,治疗,治疗和/或改善过度增殖性疾病或其症状的方法,其包括向有需要的受试者施用一种或多种免疫特异性结合甘丙肽肽的抗体。 本发明还包括用于诊断,监测和预测过度增殖性疾病的方法和组合物。 本发明进一步涉及制品和包含免疫特异性结合甘丙肽的抗体的试剂盒。