Protein S Functional Assay
    1.
    发明申请
    Protein S Functional Assay 有权
    蛋白S功能测定

    公开(公告)号:US20090081798A1

    公开(公告)日:2009-03-26

    申请号:US12273696

    申请日:2008-11-19

    IPC分类号: G01N33/68

    CPC分类号: C07K14/745 G01N33/86

    摘要: The invention relates generally to a new functional protein S assay and kit that is based on the ability of endogenous protein S to prolong clotting time. In the assay procedure, a test plasma sample is diluted with protein S deficient plasma, followed by the addition of purified or recombinant tissue factor (pTF or rTF), purified natural or synthetic phospholipid (pPL or sPL) and activated protein C (APC) or protein C activator (PCA). The clotting time is then measured and compared to a standard curve or a normal control.

    摘要翻译: 本发明一般涉及基于内源蛋白S延长凝血时间的能力的新的功能蛋白S测定和试剂盒。 在测定程序中,用蛋白S缺乏血浆稀释测试血浆样品,然后加入纯化或重组组织因子(pTF或rTF),纯化天然或合成磷脂(pPL或sPL)和活化蛋白C(APC) 或蛋白C激活剂(PCA)。 然后测量凝血时间并与标准曲线或正常对照进行比较。

    Groundwater flow measuring system
    2.
    发明授权
    Groundwater flow measuring system 失效
    地下水流量测量系统

    公开(公告)号:US06227045B1

    公开(公告)日:2001-05-08

    申请号:US09397071

    申请日:1999-09-16

    IPC分类号: G01F168

    摘要: A probe for monitoring groundwater flow seepage velocity and direction has an electrical heater and a plurality of temperature sensors located equidistant from the heater. The probe with the heater and temperature sensors is lowered into a monitoring well and positioned so as to be immersed in the groundwater. Energy is sent to the heater, and the temperature response at the temperature sensors is measured and recorded. From the measured response to temperature, the groundwater flow velocity and direction are computed and recorded. The temperature sensors may be resistance temperature detectors, thermocouples, or any other state-of-the-art temperature sensing device.

    摘要翻译: 用于监测地下水流量渗流速度和方向的探针具有电加热器和与加热器等距离的多个温度传感器。 带有加热器和温度传感器的探头下降到监测井中并定位成浸入地下水。 能量被送到加热器,测量和记录温度传感器的温度响应。 从测量的响应到温度,计算并记录地下水流速和方向。 温度传感器可以是电阻温度检测器,热电偶或任何其他现有技术的温度感测装置。

    Protein S functional assay
    4.
    发明授权
    Protein S functional assay 有权
    蛋白S功能测定

    公开(公告)号:US07468257B2

    公开(公告)日:2008-12-23

    申请号:US11013121

    申请日:2004-12-15

    IPC分类号: C12Q1/37 G01N33/86

    CPC分类号: C07K14/745 G01N33/86

    摘要: The invention relates generally to a new functional protein S assay and kit that is based on the ability of endogenous protein S to prolong clotting time. In the assay procedure, a test plasma sample is diluted with protein S deficient plasma, followed by the addition of purified or recombinant tissue factor (pTF or rTF), purified natural or synthetic phospholipid (pPL or sPL) and activated protein C (APC) or protein C activator (PCA). The clotting time is then measured and compared to a standard curve or a normal control.

    摘要翻译: 本发明一般涉及基于内源蛋白S延长凝血时间的能力的新的功能蛋白S测定和试剂盒。 在测定程序中,用蛋白S缺乏血浆稀释测试血浆样品,然后加入纯化或重组组织因子(pTF或rTF),纯化天然或合成磷脂(pPL或sPL)和活化蛋白C(APC) 或蛋白C激活剂(PCA)。 然后测量凝血时间并与标准曲线或正常对照进行比较。

    Protein S functional assay and kit therefor
    5.
    发明授权
    Protein S functional assay and kit therefor 有权
    蛋白S功能测定及其试剂盒

    公开(公告)号:US06855509B2

    公开(公告)日:2005-02-15

    申请号:US10029406

    申请日:2001-12-19

    IPC分类号: C07K14/745 G01N33/86 C12Q1/56

    CPC分类号: C07K14/745 G01N33/86

    摘要: The invention relates generally to a new functional protein S assay and kit that is based on the ability of endogenous protein S to prolong clotting time. In the assay procedure, a test plasma sample is diluted with protein S deficient plasma, followed by the addition of purified or recombinant tissue factor (pTF or rTF), purified natural or synthetic phospholipid (pPL or sPL) and activated protein C (APC) or protein C activator (PCA). The clotting time is then measured and compared to a standard curve or a normal control.

    摘要翻译: 本发明一般涉及基于内源蛋白S延长凝血时间的能力的新的功能蛋白S测定和试剂盒。 在测定程序中,用蛋白S缺乏血浆稀释测试血浆样品,然后加入纯化或重组组织因子(pTF或rTF),纯化天然或合成磷脂(pPL或sPL)和活化蛋白C(APC) 或蛋白C激活剂(PCA)。 然后测量凝血时间并与标准曲线或正常对照进行比较。