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1.发明授权公开(公告)号：US09987125B2
公开(公告)日：2018-06-05
申请号：US14804240
申请日：2015-07-20
IPC分类号： A61F2/16
CPC分类号： A61F2/1618 , A61F2/1624 , A61F2/1635 , A61F2002/1681 , A61F2002/1682 , A61F2002/1689 , A61F2250/0018
摘要： An intraocular lens for providing a range of accommodative vision, an extended depth of focus, or enhanced performance through the asymmetric transfer of ocular forces to the lens. The intraocular lens contains an optic and a haptic. The shape and/or material of the haptic results in the transmission of ocular forces to particular regions in the optic. Greater forces applied to particular regions result in deformation of that region and increased power.
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公开(公告)号：US09278026B2
公开(公告)日：2016-03-08
申请号：US13043149
申请日：2011-03-08
CPC分类号： A61F9/013 , A61F2/16 , A61F9/00 , A61F9/0008 , A61F9/0017 , A61F9/007 , A61F9/00736 , A61F9/0079 , A61F9/008 , A61F9/00838 , A61F2009/0087 , A61F2009/00889 , A61F2009/00895
摘要： Methods and apparatus treat the lens capsule so as to increase accommodation of the eye. The treatment of the lens capsule may comprise treating a portion of the lens capsule so as to stiffen the treated portion and improve accommodation of the eye. The intermediate portion of the lens capsule may located between an optically used central portion of the lens capsule and a peripheral portion of the lens capsule connected to zonules of the eye. The stiffened intermediate portion of the lens capsule can improve coupling of the peripheral portion of the lens capsule to the central portion of the lens capsule, such that an amount of accommodation of the optically used central portion of the lens is increased. As the force of the lens capsule to a lens disposed within the lens capsule is increased, the lens may comprise the natural lens of the eye or an artificial lens such as an accommodative IOL. The treatment of the eye to stiffen the intermediate portion may comprise application of one or more of an energy or a substance to the intermediate portion.
摘要翻译： 方法和装置处理晶状体囊以增加眼睛的适应性。 透镜胶囊的治疗可以包括处理透镜胶囊的一部分，以便加强经处理的部分并改善眼睛的适应性。 透镜胶囊的中间部分可以位于透镜胶囊的光学使用的中心部分和与眼睛的小区连接的透镜胶囊的周边部分之间。 透镜胶囊的加强的中间部分可以改善透镜胶囊的周边部分与透镜胶囊的中心部分的联接，使得透镜的光学中心部分的调节量增加。 当透镜胶囊对设置在透镜胶囊内的透镜的力增加时，透镜可以包括眼睛的天然晶状体或诸如调节性IOL的人造镜片。 治疗眼睛以加强中间部分可以包括向中间部分施加一种或多种能量或物质。
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3.发明授权Intraocular lens with shape changing capability to provide enhanced accomodation and visual acuity 有权具有形状变化能力的人工晶状体提供增强的住宿和视力公开(公告)号：US09084674B2
公开(公告)日：2015-07-21
申请号：US13462114
申请日：2012-05-02
申请人： Daniel G. Brady , Huawei Zhao , Edward Geraghty , Scott J. Catlin
发明人： Daniel G. Brady , Huawei Zhao , Edward Geraghty , Scott J. Catlin
IPC分类号： A61F2/16
CPC分类号： A61F2/1618 , A61F2/1624 , A61F2/1635 , A61F2002/1681 , A61F2002/1682 , A61F2002/1689 , A61F2250/0018
摘要： An intraocular lens for providing a range of accommodative vision, an extended depth of focus, or enhanced performance through the asymmetric transfer of ocular forces to the lens. The intraocular lens contains an optic and a haptic. The shape and/or material of the haptic results in the transmission of ocular forces to particular regions in the optic. Greater forces applied to particular regions result in deformation of that region and increased power.
摘要翻译： 一种眼内透镜，用于通过对眼镜的不对称转移提供一定范围的调节视力，扩大的焦点深度或增强的性能。 眼内透镜包含视神经和触觉。 触觉的形状和/或材料导致眼力传递到光学元件中的特定区域。 施加到特定区域的更大的力导致该区域的变形并增加功率。
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公开(公告)号：US08518028B2
公开(公告)日：2013-08-27
申请号：US12570780
申请日：2009-09-30
申请人： Daniel G Brady , Rakhi Jain
发明人： Daniel G Brady , Rakhi Jain
IPC分类号： A61B18/18
CPC分类号： A61F9/008 , A61F9/00736 , A61F2009/0087 , A61F2009/00889 , A61F2009/00895
摘要： The accommodative properties of the natural lens of an eye, which tend to degrade with age, can be enhanced, restored, or otherwise improved using the in situ treatment techniques and methodologies provided here. One exemplary method of enhancing accommodative properties of the natural lens of an eye involves an initial step of specifying treatment areas of the natural lens. These treatment areas correspond to regions of the capsular bag or regions of the crystalline lens. The method continues by increasing stiffness of the treatment areas while all or portions of the natural lens remains in situ. This results in stiffened areas of the natural lens that enhance transfer of ciliary muscle forces to a center region of the crystalline lens.
摘要翻译： 随着年龄的增长倾向于降解眼睛的天然晶状体的调节性能可以使用本文提供的原位治疗技术和方法进行增强，恢复或改善。 提高眼睛的天然晶状体的调节特性的一个示例性方法涉及指定天然晶状体的治疗区域的初始步骤。 这些处理区域对应于囊袋的区域或晶状体的区域。 该方法通过增加处理区域的刚度而继续，同时全部或部分天然晶状体保持原位。 这导致天然晶状体的加强区域增强了睫状肌力转移到晶状体的中心区域。
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公开(公告)号：US08465544B2
公开(公告)日：2013-06-18
申请号：US13243577
申请日：2011-09-23
申请人： Daniel G Brady , Tuyet H Nguyen , Hendrik A Weeber , Douglas S Cali , Timothy R Bumbalough , Edward P Geraghty
发明人： Daniel G Brady , Tuyet H Nguyen , Hendrik A Weeber , Douglas S Cali , Timothy R Bumbalough , Edward P Geraghty
IPC分类号： A61F2/16
CPC分类号： A61F2/1635 , A61F2002/1681 , A61F2002/169 , A61F2230/0095 , A61F2250/0018
摘要： An intraocular lens for implantation in a capsular bag of an eye includes an optic disposed about an optical axis and a haptic including a protruding portion disposed inside the optic. The optic has an anterior face and an opposing posterior face that are configured to provide a lens power. In response to an ocular force of the eye, the haptic transmits a force that alters one or more of a shape of the optic and an axial thickness of the optic. The protruding portion of the haptic has a refractive index that is equal to a refraction index of the optic for at least one a wavelength within the visible spectrum.
摘要翻译： 用于植入眼袋的眼内透镜包括围绕光轴设置的光学元件和包括设置在光学元件内部的突出部分的触觉件。 光学元件具有被配置为提供透镜光焦度的前表面和相对的后表面。 响应于眼睛的眼力，触觉件透射改变光学元件的形状和光学元件的轴向厚度中的一个或多个的力。 触觉件的突出部分具有等于可见光谱内的至少一个波长的光学器件的折射率的折射率。
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公开(公告)号：US08425597B2
公开(公告)日：2013-04-23
申请号：US12617417
申请日：2009-11-12
申请人： Robert E Glick , Daniel G Brady
发明人： Robert E Glick , Daniel G Brady
IPC分类号： A61F2/16
CPC分类号： A61F2/16 , A61F2/1613 , A61F2/1629 , A61F2/1648 , A61F2002/009 , A61F2002/16901 , A61F2002/1699 , A61F2250/0053
摘要： Intraocular lenses for providing accommodation include an anterior optic, a posterior optic, and a lens structure. In one such lens, the lens structure comprises an anterior element coupled to the anterior optic and a posterior element coupled to the posterior optic. The anterior and posterior elements are coupled to one another at a peripheral region of the intraocular lens. The intraocular lens may also includes a projection extending anteriorly from the posterior element that limits posterior motion of the anterior optic so as to maintain a minimum separation between anterior optic and an anterior surface of the posterior optic.
摘要翻译： 用于提供住宿的人造眼镜包括前视镜，后视镜和透镜结构。 在一个这样的透镜中，透镜结构包括耦合到前视镜的前元件和耦合到后光学元件的后元件。 前眼元件和后元件在眼内透镜的周边区域彼此连接。 眼内透镜还可以包括从后部元件向前延伸的突起，其限制前视镜的后运动，以便保持前视镜与后视镜的前表面之间的最小间隔。
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公开(公告)号：US20120253458A1
公开(公告)日：2012-10-04
申请号：US13243196
申请日：2011-09-23
IPC分类号： A61F2/16
CPC分类号： A61F2/1613 , A61F2/1618 , A61F2/1624 , A61F2/1635 , A61F2/164 , A61F2/1645 , A61F2/1654 , A61F2002/1681 , A61F2250/0014
摘要： An intraocular lens for providing accommodative vision includes an adjustable optic and a haptic that is operably coupled to the optic. The adjustable optic comprises a central zone and an annular zone surrounding the central zone. The optic may also comprise additional annular zones. The haptic comprises a transparent portion protruding into the adjustable optic. The intraocular lens has a disaccommodative configuration in which the central zone has a base optical power and an accommodative configuration in which the central zone has an add optical power that is at least about 1 Diopter greater than the base optical power. The central zone and the annular zone have different optical powers when the adjustable intraocular lens is in the accommodative configuration and/or when the adjustable intraocular lens is in the disaccommodative configuration.
摘要翻译： 用于提供调节视力的眼内透镜包括可操作地耦合到光学元件的可调光学元件和触觉件。 可调光学元件包括中心区域和围绕中心区域的环形区域。 光学元件还可以包括附加的环形区域。 触觉包括突出到可调节光学元件中的透明部分。 眼内透镜具有不利的配置，其中中心区域具有基本光功率和调节配置，其中中心区域具有比基本光功率大至少约1屈光度的添加光功率。 当可调节眼内透镜处于调节构型和/或当可调节眼内透镜处于不利配置时，中心区域和环形区域具有不同的光焦度。
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公开(公告)号：US07794497B2
公开(公告)日：2010-09-14
申请号：US11234597
申请日：2005-09-23
申请人： Daniel G. Brady , Tuyet H. Nguyen
发明人： Daniel G. Brady , Tuyet H. Nguyen
IPC分类号： A61F2/16
CPC分类号： A61F2/1613 , A61F2002/1681 , A61F2250/0018 , Y10S623/912
摘要： An apparatus for sizing an intraocular lens and/or an ocular region of the eye of a subject, such as the anterior chamber, contains a sizing device and a measurement device. In one embodiment, the sizing device comprises a first leg having a first contact portion for operably engaging the ocular portion and a second leg having a second contact portion for operably engaging the ocular portion. The sizing device has a test geometry when placed within the ocular portion. The measurement device is adapted for determining a dimension of the sizing device based at least in part on the test geometry. The sizing device may also have a reference geometry when the sizing device in a reference condition. In certain embodiments, the difference between the reference geometry and the test geometry may be used for sizing the intraocular lens and/or the ocular portion.
摘要翻译： 用于调整诸如前房的对象的眼睛的眼内晶状体和/或眼睛区域的尺寸的装置包含施胶装置和测量装置。 在一个实施例中，定径装置包括具有用于可操作地接合眼部的第一接触部分的第一腿部和具有用于可操作地接合眼部的第二接触部分的第二腿部。 尺寸调节装置放置在眼部内时具有测试几何形状。 测量装置适于至少部分地基于测试几何来确定尺寸调整装置的尺寸。 当尺寸调节装置处于参考状态时，尺寸调节装置也可以具有参考几何形状。 在某些实施例中，参考几何和测试几何之间的差异可用于调整眼内透镜和/或眼部分的尺寸。
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公开(公告)号：US20100198349A1
公开(公告)日：2010-08-05
申请号：US12703350
申请日：2010-02-10
IPC分类号： A61F2/16
CPC分类号： A61F2/1635 , A61F2002/1681 , A61F2002/169 , A61F2230/0095 , A61F2250/0018
摘要： An intraocular lens for implantation in a capsular bag of an eye includes an optic disposed about an optical axis and a haptic including a protruding portion disposed inside the optic. The optic has an anterior face and an opposing posterior face that are configured to provide a lens power. In response to an ocular force of the eye, the haptic transmits a force that alters one or more of a shape of the optic and an axial thickness of the optic. The protruding portion of the haptic has a refractive index that is equal to a refraction index of the optic for at least one a wavelength within the visible spectrum.
摘要翻译： 用于植入眼袋的眼内透镜包括围绕光轴设置的光学元件和包括设置在光学元件内部的突出部分的触觉件。 光学元件具有被配置为提供透镜光焦度的前表面和相对的后表面。 响应于眼睛的眼力，触觉件透射改变光学元件的形状和光学元件的轴向厚度中的一个或多个的力。 触觉件的突出部分具有等于可见光谱内的至少一个波长的光学器件的折射率的折射率。
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公开(公告)号：US07713299B2
公开(公告)日：2010-05-11
申请号：US11618325
申请日：2006-12-29
IPC分类号： A61F2/16
CPC分类号： A61F2/1635 , A61F2002/1681 , A61F2002/169 , A61F2230/0095 , A61F2250/0018
摘要： An intraocular lens is disclosed, with an optic that changes shape in response to a deforming force exerted by the zonules of the eye. A haptic supports the optic around its equator and couples the optic to the capsular bag of the eye. The region of contact between the optic and the haptic extends into the edge of the optic, similar to the interface between a bicycle tire and the rim that holds it in place. The haptic may be stiffer than the optic. The haptic may have the same refractive index as the optic. The haptic may include a saddle-shaped portion in contact with the adjustable optic, with a convex profile along an optical axis; and a concave profile in a plane perpendicular to the optical axis.
摘要翻译： 公开了一种眼内透镜，其具有响应于由眼睛的小环施加的变形力而改变形状的光学元件。 触觉件支持其赤道周围的光学器件，并将光学元件耦合到眼睛的囊袋。 光学元件和触觉件之间的接触区域延伸到光学元件的边缘，类似于自行车轮胎和将其保持在适当位置的边缘之间的界面。 触觉可能比光学元件更硬。 触觉可以具有与光学元件相同的折射率。 触觉件可以包括与可调节光学元件接触的鞍形部分，具有沿着光轴的凸形轮廓; 以及在垂直于光轴的平面中的凹形轮廓。
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