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    Method and system for diffusion magnetic resonance imaging
    2.
    发明授权
    Method and system for diffusion magnetic resonance imaging 有权
    扩散磁共振成像的方法和系统

    公开(公告)号：US08565854B2

    公开(公告)日：2013-10-22

    申请号：US12600798

    申请日：2008-05-30

    申请人： Karin Bryskhe ,  Daniel Topgaard ,  Anna Stenstam

    发明人： Karin Bryskhe ,  Daniel Topgaard ,  Anna Stenstam

    IPC分类号： A61B5/00

    CPC分类号： G01R33/4633 ,  A61B5/055 ,  G01R33/5605 ,  G01R33/56341 ,  Y10T436/24

    摘要： A method, system, computer-readable medium, use, and pulse sequence for magnetic resonance imaging or nuclear magnetic resonance is provided for determining the rate of molecular exchange between components with different diffusion characteristics. The present invention encodes the magnetic resonance signal for exchange utilizing judiciously designed protocols for varying the parameters of a pulse sequence comprising a pair of diffusion weighting blocks separated by a mixing time.

    摘要翻译： 提供用于磁共振成像或核磁共振的方法，系统，计算机可读介质，使用和脉冲序列，用于确定具有不同扩散特性的组分之间的分子交换速率。 本发明利用明智设计的协议来编码用于交换的磁共振信号，用于改变包括由混合时间分离的一对扩散加权块的脉冲序列的参数。

    METHOD AND SYSTEM FOR DIFFUSION MAGNETIC RESONANCE IMAGING
    3.
    发明申请
    METHOD AND SYSTEM FOR DIFFUSION MAGNETIC RESONANCE IMAGING 有权
    用于扩散磁共振成像的方法和系统

    公开(公告)号：US20100152567A1

    公开(公告)日：2010-06-17

    申请号：US12600798

    申请日：2008-05-30

    申请人： Karin Bryskhe ,  Daniel Topgaard ,  Anna Stenstam

    发明人： Karin Bryskhe ,  Daniel Topgaard ,  Anna Stenstam

    IPC分类号： A61B5/055

    CPC分类号： G01R33/4633 ,  A61B5/055 ,  G01R33/5605 ,  G01R33/56341 ,  Y10T436/24

    摘要： A method, system, computer-readable medium, use, and pulse sequence for magnetic resonance imaging or nuclear magnetic resonance is provided for determining the rate of molecular exchange between components with different diffusion characteristics. The present invention encodes the magnetic resonance signal for exchange utilizing judiciously designed protocols for varying the parameters of a pulse sequence comprising a pair of diffusion weighting blocks separated by a mixing time.

    摘要翻译： 提供用于磁共振成像或核磁共振的方法，系统，计算机可读介质，使用和脉冲序列，用于确定具有不同扩散特性的组分之间的分子交换速率。 本发明利用明智设计的协议来编码用于交换的磁共振信号，用于改变包括由混合时间分离的一对扩散加权块的脉冲序列的参数。

    Method and system for magnetic resonance imaging, and use thereof
    4.
    发明授权
    Method and system for magnetic resonance imaging, and use thereof 有权
    用于磁共振成像的方法和系统及其用途

    公开(公告)号：US08810244B2

    公开(公告)日：2014-08-19

    申请号：US13321332

    申请日：2010-04-22

    申请人： Daniel Topgaard

    发明人： Daniel Topgaard

    IPC分类号： G01V3/00

    CPC分类号： G01R33/56341 ,  A61B5/055 ,  G01R33/448 ,  G01R33/46 ,  G01R33/4616 ,  G01R33/50 ,  G01R33/5608

    摘要： The present invention refers to a method for magnetic resonance imaging or nuclear magnetic resonance spectroscopy comprising emitting a radio frequency and gradient pulse sequence towards an object being subjected to a magnetic field, wherein said object comprises a molecule having an atom with a nuclear spin differing from 0, encoding, detecting and acquiring a magnetic resonance signal from said object corresponding to said emitted radio frequency and gradient pulse sequence, wherein the radio frequency and gradient pulse sequence comprises a first weighting block, a mixing block with duration tm and a second weighting block, and wherein encoding, detecting and acquiring the magnetic resonance signal from said object is limited to initial decay of the signal intensity I with increasing strength of at least one of the first weighting block and the second weighting block, wherein the variation of the initial signal decay rate with tm is analysed to obtain the apparent exchange rate AXR.

    摘要翻译： 本发明涉及一种用于磁共振成像或核磁共振光谱的方法，包括向受到磁场的物体发射射频和梯度脉冲序列，其中所述物体包含具有核自旋不同原子的分子 0，编码，检测和获取对应于所述发射的射频和梯度脉冲序列的所述对象的磁共振信号，其中射频和梯度脉冲序列包括第一加权块，具有持续时间tm的混合块和第二加权块 并且其中来自所述对象的磁共振信号的编码，检测和获取被限制为随着第一加权块和第二加权块中的至少一个的增加的强度，信号强度I的初始衰减，其中初始信号的变化 分析tm的衰减率，得到表观交换率AX R.

    Method And System For Magnetic Resonance Imaging, And Use Thereof
    5.
    发明申请
    Method And System For Magnetic Resonance Imaging, And Use Thereof 有权
    磁共振成像方法与系统及其应用

    公开(公告)号：US20120062229A1

    公开(公告)日：2012-03-15

    申请号：US13321332

    申请日：2010-04-22

    申请人： Daniel Topgaard

    发明人： Daniel Topgaard

    IPC分类号： G01R33/46 ,  G01R33/48

    CPC分类号： G01R33/56341 ,  A61B5/055 ,  G01R33/448 ,  G01R33/46 ,  G01R33/4616 ,  G01R33/50 ,  G01R33/5608

    摘要： The present invention refers to a method for magnetic resonance imaging or nuclear magnetic resonance spectroscopy comprising emitting a radio frequency and gradient pulse sequence towards an object being subjected to a magnetic field, wherein said object comprises a molecule having an atom with a nuclear spin differing from 0, encoding, detecting and acquiring a magnetic resonance signal from said object corresponding to said emitted radio frequency and gradient pulse sequence, wherein the radio frequency and gradient pulse sequence comprises a first weighting block, a mixing block with duration tm and a second weighting block, and wherein encoding, detecting and acquiring the magnetic resonance signal from said object is limited to initial decay of the signal intensity I with increasing strength of at least one of the first weighting block and the second weighting block, wherein the variation of the initial signal decay rate with tm is analysed to obtain the apparent exchange rate AXR.

    摘要翻译： 本发明涉及一种用于磁共振成像或核磁共振光谱的方法，包括向受到磁场的物体发射射频和梯度脉冲序列，其中所述物体包含具有核自旋不同原子的分子 0，编码，检测和获取对应于所述发射的射频和梯度脉冲序列的所述对象的磁共振信号，其中射频和梯度脉冲序列包括第一加权块，具有持续时间tm的混合块和第二加权块 并且其中来自所述对象的磁共振信号的编码，检测和获取被限制为随着第一加权块和第二加权块中的至少一个的增加的强度的信号强度I的初始衰减，其中初始信号的变化 分析tm的衰减率，得到表观交换率AX R.