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公开(公告)号：US20120295873A1
公开(公告)日：2012-11-22
申请号：US13575757
申请日：2011-02-01
IPC分类号： C08B30/20 , C12P19/04 , A61K31/718
CPC分类号： C08B30/18 , A61K31/718 , A61K45/06 , A61M1/287 , C08B30/12 , C08B30/20 , C08L3/02 , C12P19/04 , C12P19/18 , A61K2300/00
摘要： The invention relates to branched soluble glucose polymers made of starch having an amylose content of at least 30 wt %, preferably 35 wt % to 80 wt %, having a glycosidic linkage α-1,6 content of 7% to 10%, preferably 8% to 9%, and a MW of 50,000 to 150,000 daltons, characterized in that the polymers are resistant to pancreatic alpha amylase, expressed according to a test “B” for a reducing sugar content of 25% to 35%, and a MW of released products of 6,000 to 12,000 daltons.
摘要翻译： 本发明涉及由直链淀粉含量至少为30重量％，优选35重量％至80重量％的淀粉制成的支链可溶性葡萄糖聚合物，其糖苷键α-1,6含量为7％至10％，优选8 ％至9％，MW为50,000至150,000道尔顿，其特征在于，聚合物对胰腺α淀粉酶具有抗性，根据试验B表达，还原糖含量为25％至35％，释放产物的MW 6000至12,000道尔顿。
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2.发明申请Carbohydrate Compositions Having a Greater Impact on the Insulinemic Response Than on the Glycemic Response, Their Preparation and Their Uses 有权糖尿病组合物对胰岛素反应的影响比对血糖反应及其制备及其用途有更大的影响公开(公告)号：US20110081474A1
公开(公告)日：2011-04-07
申请号：US12571684
申请日：2009-10-01
申请人： Liuming Zhou , Tom Parady , Chandani Perera , Robert Gerhardt , Daniel Wils , Dominique Baumann , Marie-Helene Degrave-Saniez
发明人： Liuming Zhou , Tom Parady , Chandani Perera , Robert Gerhardt , Daniel Wils , Dominique Baumann , Marie-Helene Degrave-Saniez
CPC分类号： A23L2/52 , A23L7/126 , A23L29/35 , A23L33/21 , A23V2002/00 , A23V2200/328 , A23V2250/5114 , A23V2250/61
摘要： The present invention describes a carbohydrate composition having a greater impact on the insulinemic response than on the glycemic response comprising a soluble dietary fiber and a glucose syrup, process to prepare it and their use in food.
摘要翻译： 本发明描述了对包含可溶性膳食纤维和葡萄糖浆的血糖反应对胰岛素应答具有更大影响的碳水化合物组合物，其制备方法及其在食品中的应用。
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3.发明申请INDIGESTIBLE POLYMER: STARCH ACETATE -BASED FILM COATINGS FOR COLON TARGETING 审中-公开可溶性聚合物：淀粉醋酸盐胶片涂料公开(公告)号：US20130078289A1
公开(公告)日：2013-03-28
申请号：US13695460
申请日：2011-04-28
IPC分类号： A61K47/36
CPC分类号： A61K47/36 , A61K9/2054 , A61K9/286 , A61K9/2866
摘要： A colon targeted delivery dosage form for controlled release of an active ingredient, includes an active ingredient coated in a polymeric mixture of: a water insoluble polymer composition containing at least a starch acetate, and an indigestible polysaccharide composition. The use and method for making the same are also described.
摘要翻译： 用于控制释放活性成分的结肠靶向递送剂型包括涂覆在聚合物混合物中的活性成分：含有至少一种淀粉乙酸酯的水不溶性聚合物组合物和不消化的多糖组合物。 还描述了制造它们的用途和方法。
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4.发明授权Process for crosslinking proteins with a ketose containing 3 to 5 carbon atoms 失效用含3至5个碳原子的酮糖交联蛋白质的方法公开(公告)号：US08034582B2
公开(公告)日：2011-10-11
申请号：US11012485
申请日：2004-12-16
申请人： Daniel Wils , Catherine Fouache
发明人： Daniel Wils , Catherine Fouache
CPC分类号： C08H1/00 , A23K20/147 , A23K50/10 , A23K50/40 , A23K50/80 , C07K1/1077 , Y02A40/818
摘要： The present invention relates to a process for crosslinking proteins, according to which the crosslinking agent is a ketose containing 3 to 5 carbon atoms and said proteins are chosen from the group comprising proteins from animal tissues, from milk or from blood, such as in particular casein, gelatin or collagen; proteins from cereals, such as in particular maize, wheat or rice proteins; protein from high-protein plants, such as in particular pea, alfalfa, lupin, barley, millet or sorghum proteins; proteins from oleaginous plants, such as in particular soybean proteins, for instance soybean cakes, rapeseed or flax proteins, for instance rapeseed cakes, sunflower, groundnut or cotton proteins; and proteins from tubers, such as in particular from potato or manioc.
摘要翻译： 本发明涉及交联蛋白质的方法，根据该方法，交联剂是含有3-5个碳原子的酮糖酮，所述蛋白质选自包含来自动物组织，牛奶或血液的蛋白质的组 酪蛋白，明胶或胶原蛋白; 来自谷物的蛋白质，特别是玉米，小麦或水稻蛋白质; 蛋白质，例如特别是豌豆，苜蓿，羽扇豆，大麦，小米或高粱蛋白质的蛋白质; 来自油质植物的蛋白质，例如特别是大豆蛋白质，例如大豆蛋糕，油菜籽或亚麻蛋白质，例如油菜籽蛋糕，向日葵，花生或棉花蛋白质; 和来自块茎的蛋白质，特别是来自马铃薯或manioc的蛋白质。
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公开(公告)号：US07704974B2
公开(公告)日：2010-04-27
申请号：US11594194
申请日：2006-11-08
申请人： Daniel Wils , Laëtitia Deremaux
发明人： Daniel Wils , Laëtitia Deremaux
IPC分类号： A61K31/715 , A01N43/04
CPC分类号： A61K31/047 , A23L33/10 , A23V2002/00 , A61K31/721 , A23V2200/30 , A23V2250/64
摘要： The present invention relates to a method for the treatment and/or prevention of urinary disorders, comprising administering an effective amount of an osmotic diuretic agent and an effective amount of an appetence-inducing agent to a subject in need thereof.
摘要翻译： 本发明涉及一种治疗和/或预防尿失调的方法，包括向有需要的受试者施用有效量的渗透性利尿剂和有效量的开胃诱导剂。
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6.发明授权Water insoluble polymer: indigestible water-soluble polysaccharide film coatings for colon targeting 有权水不溶性聚合物：难消化的水溶性多糖薄膜包衣用于结肠靶向公开(公告)号：US09107819B2
公开(公告)日：2015-08-18
申请号：US13126236
申请日：2009-10-27
申请人： Olaf Haeusler , Daniel Wils , Juergen Siepmann , Youness Karrout
发明人： Olaf Haeusler , Daniel Wils , Juergen Siepmann , Youness Karrout
CPC分类号： A61K9/0053 , A61K9/2826 , A61K9/2846 , A61K47/36
摘要： A controlled release pharmaceutical dosage form for controlled release of an active ingredient, includes an active ingredient coated by a polymeric mixture of: at least a water insoluble polymer; and at least an indigestible water-soluble oligosaccharide. The use and method of making the same are also described.
摘要翻译： 用于控制释放活性成分的控制释放药物剂型包括通过至少一种水不溶性聚合物的聚合物混合物包被的活性成分; 和至少难消化的水溶性寡糖。 还描述了制造它们的用途和方法。
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7.发明授权Carbohydrate compositions having a greater impact on the insulinemic response than on the glycemic response, their preparation and their uses 有权碳水化合物组合物对胰岛素反应的影响比对血糖反应，它们的制备及其用途具有更大的影响公开(公告)号：US08617636B2
公开(公告)日：2013-12-31
申请号：US12571684
申请日：2009-10-01
申请人： Liuming Zhou , Tom Parady , Chandani Perera , Robert Gerhardt , Daniel Wils , Dominique Baumann , Marie-Helene Degrave-Saniez
发明人： Liuming Zhou , Tom Parady , Chandani Perera , Robert Gerhardt , Daniel Wils , Dominique Baumann , Marie-Helene Degrave-Saniez
CPC分类号： A23L2/52 , A23L7/126 , A23L29/35 , A23L33/21 , A23V2002/00 , A23V2200/328 , A23V2250/5114 , A23V2250/61
摘要： The present invention describes a carbohydrate composition having a greater impact on the insulinemic response than on the glycemic response comprising a soluble dietary fiber and a glucose syrup, process to prepare it and their use in food.
摘要翻译： 本发明描述了对包含可溶性膳食纤维和葡萄糖浆的血糖反应具有对胰岛素反应影响更大影响的碳水化合物组合物，其制备方法及其在食品中的应用。
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公开(公告)号：US20060142254A1
公开(公告)日：2006-06-29
申请号：US11360594
申请日：2006-02-24
申请人： Daniel Wils , Roselyne Bernard
发明人： Daniel Wils , Roselyne Bernard
IPC分类号： A61K31/60 , A61K31/045
CPC分类号： A61K31/047 , A61K31/60 , A61K45/06
摘要： The invention relates to an antipyretic preparation intended to be administered by any means other than orally, characterized in that it comprises xylitol, and more particularly to an antipyretic preparation characterized in that it consists of an antipyretic and a synergistic amount of xylitol. The invention also relates to the use of this antipyretic preparation in pharmaceutical applications, in which the xylitol can then be used as a medicinal product with an antipyretic effect, for example in combination with another medicinal product of the family of antipyretic analgesics which may or may not have anti-inflammatory action. It also relates to its use in the treatment of infections chosen from the group of parasitic, viral and bacterial infections, but also in the treatment of heatstroke, burns, poisoning with a chemical product or any disturbance of the function of body temperature regulation.
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公开(公告)号：US08871740B2
公开(公告)日：2014-10-28
申请号：US13519006
申请日：2010-12-23
IPC分类号： A61K31/715 , A61K31/718 , A61K45/06 , A61K31/55
CPC分类号： A61K45/06 , A61K31/55 , A61K31/715 , A61K31/718 , A61K2300/00
摘要： The present invention relates to a composition including a mix of a polysaccharides having: 15% to 50% of glucoside linkages 1-6; a reducing sugar content of less than 20%; a polymolecularity index of less than 5; an average molecular weight with number Mn of less than 4500 g/mole and at least one active agent for treating stress, anxiety and depressive behavior, sleep disorders, obsessive-compulsive disorder, bulimia and epilepsy in humans or animals. The present invention also relates to the use of the polysaccharide for treating stress, anxiety or depressive behavior, sleep disorders, obsessive-compulsive disorder, bulimia and epilepsy in humans or animals.
摘要翻译： 本发明涉及包含多糖的混合物的组合物，所述多糖具有：15％至50％的葡萄糖苷键1-6; 还原糖含量小于20％; 多分子指数小于5; 数量Mn小于4500g / mol的平均分子量和用于治疗人或动物中的压力，焦虑和抑郁行为，睡眠障碍，强迫症，贪食症和癫痫的至少一种活性剂。 本发明还涉及多糖用于治疗人或动物中的压力，焦虑或抑郁行为，睡眠障碍，强迫症，贪食症和癫痫的用途。
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公开(公告)号：US20120283212A1
公开(公告)日：2012-11-08
申请号：US13519006
申请日：2010-12-23
IPC分类号： A61K31/715 , A61P25/00 , A61P25/08 , A61P25/22 , A61P25/24
CPC分类号： A61K45/06 , A61K31/55 , A61K31/715 , A61K31/718 , A61K2300/00
摘要： The present invention relates to a composition including a mix of a polysaccharides having: 15% to 50% of glucoside linkages 1-6; a reducing sugar content of less than 20%; a polymolecularity index of less than 5; an average molecular weight with number Mn of less than 4500 g/mole and at least one active agent for treating stress, anxiety and depressive behaviour, sleep disorders, obsessive-compulsive disorder, bulimia and epilepsy in humans or animals. The present invention also relates to the use of the polysaccharide for treating stress, anxiety or depressive behaviour, sleep disorders, obsessive-compulsive disorder, bulimia and epilepsy in humans or animals.
摘要翻译： 本发明涉及包含多糖的混合物的组合物，所述多糖具有：15％至50％的葡萄糖苷键1-6; 还原糖含量小于20％; 多分子指数小于5; 数量Mn小于4500g / mol的平均分子量和用于治疗人或动物中的压力，焦虑和抑郁行为，睡眠障碍，强迫症，贪食症和癫痫的至少一种活性剂。 本发明还涉及多糖用于治疗人或动物中的压力，焦虑或抑郁行为，睡眠障碍，强迫症，贪食症和癫痫的用途。
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