-
公开(公告)号:US20100297177A1
公开(公告)日:2010-11-25
申请号:US12601639
申请日:2008-06-02
申请人: Hildegard Buening , John Nieland , Luca Perabo , Daniela Kuehn , Kerstin Lux , Michael Hallek , Markus Hoerer , Mirko Ritter
发明人: Hildegard Buening , John Nieland , Luca Perabo , Daniela Kuehn , Kerstin Lux , Michael Hallek , Markus Hoerer , Mirko Ritter
IPC分类号: A61K39/23 , C40B30/04 , C07K14/00 , C07H21/04 , C12N7/01 , C12P21/00 , A61K38/00 , A61P37/04
CPC分类号: G01N33/56983 , A61K39/00 , A61K2039/5256 , C07K14/005 , C07K16/081 , C07K16/4291 , C07K2317/34 , C07K2317/76 , C12N2750/14122 , C12N2750/14143 , G01N2333/015 , G01N2500/04
摘要: The present invention is related to a method for identifying a parvovirus mutated structural protein capable of specifically binding to a binder for an antigen, a parvovirus mutated structural protein which comprises at least one B-cell epitope heterologous to the parvovirus, a multimeric structure comprising the protein, a nucleic acid encoding the protein, a virus or cell comprising the protein, a method of preparing the protein, a medicament comprising the protein, nucleic acid or multimeric structure and its use.
摘要翻译: 本发明涉及用于鉴定能够特异性结合抗原的粘合剂的细小病毒突变结构蛋白的方法,包括至少一个与细小病毒异源的B细胞表位的细小病毒突变的结构蛋白,包含 蛋白质,编码蛋白质的核酸,包含蛋白质的病毒或细胞,制备蛋白质的方法,包含蛋白质,核酸或多聚体结构的药物及其用途。
-
公开(公告)号:US20050202556A1
公开(公告)日:2005-09-15
申请号:US11023372
申请日:2004-12-29
申请人: Walter Gumbrecht , Daniela Kuehn , Manfred Stanzel
发明人: Walter Gumbrecht , Daniela Kuehn , Manfred Stanzel
IPC分类号: B01J19/00 , B05D3/00 , C12M1/34 , C12Q1/68 , C40B60/14 , G01N33/50 , G01N33/543 , G01N33/544
CPC分类号: G01N33/544 , B01J19/0046 , B01J2219/00351 , B01J2219/00639 , B01J2219/00644 , B01J2219/00659 , C40B60/14 , G01N33/54353 , G01N33/5436
摘要: A process is proposed for preparing a microarray including a multiplicity of analytical positions or spots and arranged on a support. The spots include probe molecules and a polymer which has been solidified to give a film. A spot is generated by applying an initially flowable spotting solution to the support, which solution includes a polymer and probe molecules, the polymer being solidified after application to the support. A spotting solution is further proposed which includes, in aqueous solution, probe molecules and a polymer which can be solidified in a non-free radical manner.
摘要翻译: 提出了一种制备包含多个分析位置或斑点并布置在载体上的微阵列的方法。 斑点包括探针分子和已经固化得到膜的聚合物。 通过将初始可流动的点样溶液施加到载体上来产生斑点,该溶液包括聚合物和探针分子,聚合物在施用于载体之后固化。 进一步提出了一种检测溶液,其包括在水溶液中,探针分子和可以以非自由基方式固化的聚合物。
-