公开(公告)号：US07670384B2

公开(公告)日：2010-03-02

申请号：US11407409

申请日：2006-04-19

申请人： Mukesh Kumar ,  Ned M. Hamman ,  Michael D. Leach ,  John Manocchio ,  Paul D'Antonio ,  Daryl L. Carter

发明人： Mukesh Kumar ,  Ned M. Hamman ,  Michael D. Leach ,  John Manocchio ,  Paul D'Antonio ,  Daryl L. Carter

IPC分类号： A61F2/28 ,  A61K35/32

CPC分类号： A61L27/365 ,  A61L27/3608 ,  A61L27/3683 ,  A61L27/3691 ,  A61L2430/02 ,  A61M5/204 ,  A61M5/3129

摘要： Formed compositions for application to a bone surface of a human or animal subject, comprising: a bone material; and a carrier comprising denatured demineralized bone, where the composition is formed into a shape suitable for administration to the bone. Methods are provided for making formed compositions for application to a bone surface of a human or animal subject comprise mixing a demineralized bone and water; heating the mixture to form a carrier; mixing the carrier with bone to form a moldable composition; and molding the moldable composition to produce a formed composition. Several apparatuses are provided in which to hydrate the formed bone composition. Methods of hydrating a formed bone composition are also provided.

摘要翻译： 用于施用于人或动物受试者的骨表面的成形组合物，包括：骨材料; 以及包含变性软化骨的载体，其中所述组合物形成适于施用于骨的形状。 提供用于制备用于施用于人或动物对象的骨表面的成形组合物的方法包括混合脱矿质骨和水; 加热混合物形成载体; 将载体与骨混合以形成可成型组合物; 并模塑可模制组合物以产生形成的组合物。 提供了几种用于水合形成的骨组合物的装置。 还提供了水合形成的骨组合物的方法。