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    Non-spherical and non-platelet forms of pyrithione salts and methods of making same
    2.
    发明授权
    Non-spherical and non-platelet forms of pyrithione salts and methods of making same 有权
    非球形和非血小板形式的吡啶硫酮盐及其制备方法

    公开(公告)号：US06242007B1

    公开(公告)日：2001-06-05

    申请号：US09410687

    申请日：1999-10-01

    申请人： Saeed H. Mohseni ,  John J. Jardas ,  George Polson ,  David C. Beaty ,  Charles W. Kaufman

    发明人： Saeed H. Mohseni ,  John J. Jardas ,  George Polson ,  David C. Beaty ,  Charles W. Kaufman

    IPC分类号： A61K706

    CPC分类号： A61Q19/00 ,  A01N43/40 ,  A61K8/02 ,  A61K8/4933 ,  A61K31/44 ,  A61K2800/412 ,  A61Q5/006 ,  A61Q5/02 ,  C07D213/89 ,  A01N2300/00

    摘要： The present invention relates to non-spherical and/or non-platelet pyrithione particles. Also disclosed is a method for producing non-spherical and/or non-platelet particles of pyrithione salts, comprising reacting pyrithione acid or a water-soluble salt of pyrithione and a water-soluble polyvalent metal salt in the presence of an ionic surfactant composition at temperature from about 20° C. to about 60° C. and at a pH from 4-9 to produce non-spherical and/or non-platelet particles of pyrithione salts. The present invention further relates to particles made by the above methods and products, such as shampoos, soaps, and skin-care medicaments made using these particles.

    摘要翻译： 本发明涉及非球形和/或非血小板吡啶硫酮颗粒。 还公开了一种用于生产吡啶硫酮盐的非球形和/或非血小板颗粒的方法，包括在离子表面活性剂组合物存在下使吡啶硫酮酸或吡啶硫酮的水溶性盐与水溶性多价金属盐反应 温度为约20℃至约60℃，pH为4-9，以产生吡啶硫酮盐的非球形和/或非血小板颗粒。 本发明还涉及通过上述方法制成的颗粒，以及使用这些颗粒制成的洗发剂，肥皂和护​​肤品等产品。