公开(公告)号：US08814947B2

公开(公告)日：2014-08-26

申请号：US11729637

申请日：2007-03-29

申请人： David J. Callaghan

发明人： David J. Callaghan

IPC分类号： A61F2/02

CPC分类号： A61B17/0057 ,  A61B2017/00575 ,  A61B2017/00592 ,  A61B2017/00606 ,  A61B2017/00619 ,  A61B2017/00623 ,  A61B2017/00862

摘要： Devices, delivery systems, and delivery techniques for an occlusion device for closure of physical anomalies, such as an atrial septal defect, a patent foramen ovale (PFO), and other septal and vascular defects are described. Specifically, an occluder with a catch member that holds the occluder in the deployed, expanded profile configuration is provided within a delivery sheath. The proximal end of the catch member includes a flap that when positioned proximal to the proximal end of the occluder holds the occluder in the expanded profile configuration. The flap is sized and formed of a material that allows the flap to deform by bending back and forth in axial and radial directions. In certain embodiments, the flap has segments divided by notches. In certain embodiments, deforming the flap in the proximal direction requires a different amount of force than deforming the flap in the distal direction.

摘要翻译： 描述了用于闭合物理异常的闭塞装置的装置，输送系统和输送技术，例如房间隔缺损，卵圆孔专利（PFO）以及其它间隔和血管缺陷。 具体而言，在输送护套内设置有具有将封堵器保持在展开的扩张型材构造中的止动件的封堵器。 捕获构件的近端包括翼片，当定位在封闭器的近端附近时，将封堵器保持在膨胀的轮廓构造中。 该襟翼的尺寸和形状由允许襟翼通过在轴向和径向方向来回弯曲而变形的材料形成。 在某些实施例中，翼片具有由切口划分的段。 在某些实施例中，使翼片沿近端方向变形需要与翼片在远侧方向上的变形不同的力量。

公开(公告)号：US08480706B2

公开(公告)日：2013-07-09

申请号：US11395718

申请日：2006-03-31

申请人： Andrzej J. Chanduszko ,  David J. Callaghan

发明人： Andrzej J. Chanduszko ,  David J. Callaghan

IPC分类号： A61B17/08 ,  A61D1/00

CPC分类号： A61B17/0057 ,  A61B2017/00575 ,  A61B2017/00592 ,  A61B2017/00606 ,  A61B2017/00619 ,  A61B2017/00623

摘要： The present invention provides a device for occluding an anatomical aperture, such as an atrial septal defect (ASD) or a patent foramen ovale (PFO). The occluder includes two sides connected by a central tube. The occluder is formed from a tube, which is cut to produce struts in each side. Upon the application of force, the struts deform into loops. The loops may be of various shapes, sizes, and configurations, and, in at least some embodiments, the loops have rounded peripheries. In some embodiments, at least one of the sides includes a tissue scaffold. The occluder further includes a catch system that maintains its deployed state in vivo. When the occluder is deployed in vivo, the two sides are disposed on opposite sides of the septal tissue surrounding the aperture and the catch system is deployed so that the occluder exerts a compressive force on the septal tissue and closes the aperture.

公开(公告)号：US08764848B2

公开(公告)日：2014-07-01

申请号：US11235661

申请日：2005-09-26

申请人： David J. Callaghan ,  Noel McLellan

发明人： David J. Callaghan ,  Noel McLellan

IPC分类号： A61F2/02

CPC分类号： A61B17/0057 ,  A61B2017/00243 ,  A61B2017/00575 ,  A61B2017/00592 ,  A61B2017/00606 ,  A61B2017/00619 ,  A61B2017/00623 ,  A61B2017/00867 ,  A61B2017/12054 ,  A61B2017/12095

摘要： Devices, delivery systems and delivery techniques for an occlusion device for the closure of physical anomalies, such as an atrial septal defect, a patent foramen ovale (PFO), and other septal and vascular defects are described. The devices, delivery systems and delivery techniques relate particularly to, but are not limited to, a patent foramen ovale (PFO) occluder made from a polymer tube. Specifically, a petal-shaped occluder with a catch system is provided within a delivery sheath. In certain embodiments, the delivery system includes a first securement system for securing a first end of the occluder and a second securement system for securing a second end of the occluder to a delivery catheter and a delivery wire contained in the delivery system. The securement enable the deployment (and retrieval) of the device. The securement systems enable pushing and pulling of respective ends of the occluder to expand and contract the device by varying its axial length. In one aspect, the first securement system employs a threaded connection and the second securement system employs a suture connection. In another aspect, the first securement system employs a threaded connection and the second securement system employs a collet finger connection. The securement systems are detached when the device has been properly positioned. The securement systems can be manipulated by control systems provided in the control portion of the delivery system.

摘要翻译： 描述了用于闭合物理异常的闭塞装置的装置，输送系统和输送技术，例如房间隔缺损，卵圆孔卵孔（PFO）以及其他间隔和血管缺陷。 装置，输送系统和输送技术特别涉及但不限于由聚合物管制成的卵圆孔（PFO）封堵器。 具体而言，在输送鞘内设置具有捕获系统的花瓣状封堵器。 在某些实施例中，输送系统包括用于固定封堵器的第一端的第一固定系统和用于将封堵器的第二端固定到输送导管和包含在输送系统中的输送线的第二固定系统。 该安全性使得能够部署（和检索）设备。 固定系统能够推动和拉动封堵器的各个端部，以通过改变其轴向长度来膨胀和收缩装置。 在一个方面，第一固定系统采用螺纹连接，而第二固定系统采用缝线连接。 在另一方面，第一固定系统采用螺纹连接，而第二固定系统采用夹头连接。 当设备正确定位时，固定系统被拆卸。 固定系统可以由在输送系统的控制部分中提供的控制系统来操纵。

公开(公告)号：US20100312236A1

公开(公告)日：2010-12-09

申请号：US12856654

申请日：2010-08-15

申请人： Sean Forde ,  James Scutti ,  David J. Callaghan ,  Eric Glaser ,  Carol Devellian ,  Steven Opolski

发明人： Sean Forde ,  James Scutti ,  David J. Callaghan ,  Eric Glaser ,  Carol Devellian ,  Steven Opolski

IPC分类号： A61B18/18 ,  A61B18/14

CPC分类号： A61B18/1492 ,  A61B2017/00575 ,  A61B2017/00592 ,  A61B2017/00606 ,  A61B2018/00351 ,  A61B2018/1435

摘要： The present invention provides systems and methods for occluding or closing a patent foramen ovale of a patient (PFO). The invention includes a catheter carrying an energy delivery element. The catheter introduces the energy delivery element into the patent foramen ovale of a patient's heart. Once appropriately positioned, the energy delivery element applies energy, such as radiofrequency energy, to the tissues surrounding the patent foramen ovale. The application of energy causes the tissues to join together, occluding the patent foramen ovale. The energy delivery element may be removable or permanently implanted in the patent foramen ovale.

摘要翻译： 本发明提供了用于闭塞或闭合患者（PFO）的卵孔专利的系统和方法。 本发明包括承载能量输送元件的导管。 导管将能量递送元件引入患者心脏的卵孔中。 一旦适当定位，能量传递元件将能量（例如射频能量）施加到卵孔卵孔周围的组织。 能量的应用导致组织结合在一起，阻塞卵巢卵泡的专利。 能量输送元件可以是可移除的或永久地植入卵孔的专利。

公开(公告)号：US20150345927A1

公开(公告)日：2015-12-03

申请号：US14290003

申请日：2014-05-29

申请人： Bernard J. Bourque ,  David J. Callaghan

发明人： Bernard J. Bourque ,  David J. Callaghan

IPC分类号： G01B5/06

CPC分类号： A61B90/06 ,  A61B17/1615 ,  A61B17/1633 ,  A61B17/1675 ,  A61B17/1714 ,  A61B2017/00902 ,  A61B2090/062 ,  G01B5/06

摘要： A thickness gage including a transparent measurement tube configured to receive and be slidingly engaged over a tubular shaft of a retrograde reamer. The tubular shaft has linear graduation marks on its surface for identifying linear measures for use in measuring a thickness of a bridge bone gap. The linear graduation marks are located on the tubular shaft surface such that at least some of the linear graduation marks can be observed through the transparent measurement tube. Each linear graduation mark, when aligned with a proximal end of the measurement tube, provides a linear measure of the distance between a distal end of the measurement tube and a cutting member of the retrograde reamer positioned so that its central axis is disposed at a non-zero angle relative to a longitudinal axis of the tubular shaft. Such a distance corresponds to the thickness of the bridge bone gap.

摘要翻译： 一种厚度计，包括透明测量管，其构造成容纳并滑动地接合在逆行铰刀的管状轴上。 管状轴在其表面上具有线性刻度标记，用于确定用于测量桥骨间隙厚度的线性测量。 线性刻度标记位于管状轴表面上，使得可以通过透明测量管观察至少一些线性刻度标记。 当与测量管的近端对准时，每个线性刻度标记提供了测量管的远端与逆行铰刀的切割构件之间的距离的线性测量，其位于使其中心轴线处于非轴向 相对于管状轴的纵向轴线为零。 这样的距离对应于桥骨间隙的厚度。

公开(公告)号：US08795329B2

公开(公告)日：2014-08-05

申请号：US12856654

申请日：2010-08-15

申请人： Sean Forde ,  James Scutti ,  David J. Callaghan ,  Erik Glaser ,  Carol A. Devellian ,  Steve W Opolski

发明人： Sean Forde ,  James Scutti ,  David J. Callaghan ,  Erik Glaser ,  Carol A. Devellian ,  Steve W Opolski

IPC分类号： A61B17/04

CPC分类号： A61B18/1492 ,  A61B2017/00575 ,  A61B2017/00592 ,  A61B2017/00606 ,  A61B2018/00351 ,  A61B2018/1435

摘要： The present invention provides systems and methods for occluding or closing a patent foramen ovale of a patient (PFO). The invention includes a catheter carrying an energy delivery element. The catheter introduces the energy delivery element into the patent foramen ovale of a patient's heart. Once appropriately positioned, the energy delivery element applies energy, such as radiofrequency energy, to the tissues surrounding the patent foramen ovale. The application of energy causes the tissues to join together, occluding the patent foramen ovale. The energy delivery element may be removable or permanently implanted in the patent foramen ovale.

摘要翻译： 本发明提供了用于闭塞或闭合患者（PFO）的卵孔专利的系统和方法。 本发明包括承载能量输送元件的导管。 导管将能量递送元件引入患者心脏的卵孔中。 一旦适当定位，能量传递元件将能量（例如射频能量）施加到卵孔卵孔周围的组织。 能量的应用导致组织结合在一起，阻塞卵巢卵泡的专利。 能量输送元件可以是可移除的或永久地植入卵孔的专利。

公开(公告)号：US08109946B2

公开(公告)日：2012-02-07

申请号：US11729636

申请日：2007-03-29

申请人： Ryan Cahill ,  John Ahern ,  Timothy J. Fallon ,  Steven W. Opolski ,  David J. Callaghan

发明人： Ryan Cahill ,  John Ahern ,  Timothy J. Fallon ,  Steven W. Opolski ,  David J. Callaghan

IPC分类号： A61B17/08

CPC分类号： A61B17/0057 ,  A61B2017/00575 ,  A61B2017/00592 ,  A61B2017/00606 ,  A61B2017/00619 ,  A61B2017/00623 ,  A61B2017/00862 ,  A61B2017/00867

摘要： Devices, delivery systems and techniques for an occlusion device for the closure of physical anomalies, such as an atrial septal defect, a patent foramen ovale (PFO), and other septal and vascular defects are described. The devices, delivery systems and techniques relate to, but are not limited to, a patent foramen ovale (PFO) occluder made from a substantially cylindrical form. An occluder having a distal side and a proximal side, with a catch system for securing the deployed configuration, is introduced into the treatment site by a delivery sheath. In one aspect, the occluder has an adjustable length center joint that allows the device to fit a particular septal defect. In some embodiments, the occluder includes a catch member that holds the occluder in the deployed, expanded profile configuration. In one aspect, the catch member also has an adjustable length.

摘要翻译： 描述了用于闭合物理异常的闭塞装置的装置，输送系统和技术，例如房间隔缺损，卵圆孔卵孔（PFO）以及其它间隔和血管缺陷。 装置，输送系统和技术涉及但不限于由基本上圆柱形形式制成的卵圆孔（PFO）封堵器。 具有远侧和近侧的封堵器，具有用于固定展开构型的捕获系统，通过输送护套引入治疗部位。 在一个方面，封堵器具有可调整的中心关节，允许该装置适合特定的间隔缺损。 在一些实施例中，封堵器包括将封堵器保持在展开的扩张型材配置中的捕捉构件。 在一个方面，捕捉构件也具有可调整的长度。

公开(公告)号：US20110146692A1

公开(公告)日：2011-06-23

申请号：US12646317

申请日：2009-12-23

申请人： David J. Callaghan ,  Jeffrey Model ,  Matthew LaPlaca

发明人： David J. Callaghan ,  Jeffrey Model ,  Matthew LaPlaca

IPC分类号： A61F6/06 ,  A61B17/00 ,  A61B18/18

CPC分类号： A61F6/225 ,  A61B18/14 ,  A61B90/39 ,  A61F6/06

摘要： Devices and methods are disclosed for the delivery of a compressible implant into a bodily lumen. The delivery device includes an enlarged section that is configured to house the implant during delivery thereof into a patient. In certain embodiments, the implant is kept within the delivery device in a substantially uncompressed configuration prior to the delivery thereof.

摘要翻译： 公开了用于将可压缩植入物递送到体腔中的装置和方法。 递送装置包括放大部分，其被配置为在植入物递送到患者体内时容纳植入物。 在某些实施例中，植入物在其递送之前以基本上未压缩的构型保持在输送装置内。

公开(公告)号：US07797056B2

公开(公告)日：2010-09-14

申请号：US11516145

申请日：2006-09-06

申请人： Sean Forde ,  James Scutti ,  David J. Callaghan ,  Eric Glaser ,  Carol Devellian ,  Steven Opolski

发明人： Sean Forde ,  James Scutti ,  David J. Callaghan ,  Eric Glaser ,  Carol Devellian ,  Steven Opolski

IPC分类号： A61N1/00

CPC分类号： A61B18/1492 ,  A61B2017/00575 ,  A61B2017/00592 ,  A61B2017/00606 ,  A61B2018/00351 ,  A61B2018/1435

摘要： The present invention provides systems and methods for occluding or closing a patent foramen ovale of a patient (PFO). The invention includes a catheter carrying an energy delivery element. The catheter introduces the energy delivery element into the patent foramen ovale of a patient's heart. Once appropriately positioned, the energy delivery element applies energy, such as radiofrequency energy, to the tissues surrounding the patent foramen ovale. The application of energy causes the tissues to join together, occluding the patent foramen ovale. The energy delivery element may be removable or permanently implanted in the patent foramen ovale.

摘要翻译： 本发明提供了用于闭塞或闭合患者（PFO）的卵孔专利的系统和方法。 本发明包括承载能量输送元件的导管。 导管将能量递送元件引入患者心脏的卵孔中。 一旦适当定位，能量传递元件将能量（例如射频能量）施加到卵孔卵孔周围的组织。 能量的应用导致组织结合在一起，阻塞卵巢卵泡的专利。 能量输送元件可以是可移除的或永久地植入卵孔的专利。

公开(公告)号：US09861346B2

公开(公告)日：2018-01-09

申请号：US11728694

申请日：2007-03-27

申请人： David J. Callaghan

发明人： David J. Callaghan

IPC分类号： A61B17/00 ,  A61B17/12

CPC分类号： A61B17/0057 ,  A61B2017/00575 ,  A61B2017/00592 ,  A61B2017/00606 ,  A61B2017/00619 ,  A61B2017/00623 ,  A61B2017/00862 ,  A61B2017/12054

摘要： The present invention provides a device for occluding an anatomical aperture, such as an atrial septal defect (ASD) or a patent foramen ovale (PFO). The occluder includes two sides connected by a central tube. In some embodiments, the occluder is formed from filaments that are joined together to define a substantially cylindrical form with openings defining struts. Upon the application of force, the struts deform into loops. The loops may be of various shapes, sizes, and configurations, and, in at least some embodiments, the loops have rounded peripheries. The occluder further includes a catch system that maintains its deployed state in vivo. When the occluder is deployed in vivo, the two sides are disposed on opposite sides of the septal tissue surrounding the aperture and the catch system is engaged so that the occluder closes the aperture.