公开(公告)号：US4052010A

公开(公告)日：1977-10-04

申请号：US447250

申请日：1974-03-01

申请人： Frederick G. Baker ,  David L. Eaton

发明人： Frederick G. Baker ,  David L. Eaton

IPC分类号： A61K39/44 ,  C03C11/00 ,  C03C12/00 ,  C03C23/00 ,  G01N33/552 ,  B02C23/08 ,  B02C23/20

CPC分类号： C03C23/008 ,  A61K39/44 ,  C03C11/00 ,  C03C12/00 ,  G01N33/552 ,  Y10S436/804

摘要： An aqueous suspension of porous glass particles having a closely controlled average particle size within the range of about 0.7 to about 3.0 microns. The controlled particle size porous glass particles are prepared by initially milling course porous glass particles to yield particles of about 10 microns or less, leaching those particles to remove contaminants and residues, rinsing the particles, and then mixing the particles with an aqueous solution and subjecting the mixture to at least two controlled sedimentation steps.

公开(公告)号：US07706046B2

公开(公告)日：2010-04-27

申请号：US10863638

申请日：2004-06-08

申请人： Frederick T. Bauer ,  Robert R. Turnbull ,  Thomas F. Guarr ,  Leroy J. Kloeppner ,  David L. Eaton ,  Joel A. Stray ,  Barry K. Nelson

发明人： Frederick T. Bauer ,  Robert R. Turnbull ,  Thomas F. Guarr ,  Leroy J. Kloeppner ,  David L. Eaton ,  Joel A. Stray ,  Barry K. Nelson

IPC分类号： G02F1/153

CPC分类号： B60R1/12 ,  B60R1/088 ,  H05K1/0274 ,  H05K1/0306 ,  H05K3/321 ,  H05K2201/0108 ,  H05K2201/10106 ,  H05K2201/10651 ,  H05K2201/2036 ,  H05K2201/2054

摘要： According to the present invention, a rearview mirror comprises a first substrate having a front surface and a rear surface, a reflective coating disposed on a surface of the first substrate, and an electronic circuit component secured to the rear surface of the first substrate. The mirror element may be an electrochromic mirror element comprising a transparent second substrate positioned in front of the first substrate. The electronic component secured to the rear surface may be a component of a drive circuit for the electrochromic mirror element. The rearview mirror element may further comprise electrically conductive tracings provided on the rear surface of the first substrate electrically coupled to the electrical component. The tracings may be used to electrically couple the drive circuit to the electrodes of the electrochromic mirror element. The tracings may be deposited on the rear surface using numerous methods including inkjet printing techniques.

摘要翻译： 根据本发明，后视镜包括具有前表面和后表面的第一基板，设置在第一基板的表面上的反射涂层以及固定到第一基板的后表面的电子电路部件。 镜元件可以是电致变色镜元件，其包括位于第一衬底前面的透明第二衬底。 固定到后表面的电子部件可以是用于电致变色镜元件的驱动电路的部件。 后视镜元件还可以包括设置在电耦合到电气部件的第一基板的后表面上的导电跟踪。 跟踪可以用于将驱动电路电耦合到电致变色镜元件的电极。 可以使用包括喷墨印刷技术的许多方法将痕迹沉积在后表面上。

公开(公告)号：US20080124407A1

公开(公告)日：2008-05-29

申请号：US11867299

申请日：2007-10-04

申请人： David L. Eaton ,  Kenneth Thummel ,  Changcheng Zhou ,  Theo Bammler

发明人： David L. Eaton ,  Kenneth Thummel ,  Changcheng Zhou ,  Theo Bammler

IPC分类号： A61K36/38 ,  A61K31/26 ,  A61P9/12 ,  A61K31/5517 ,  A61K31/497

CPC分类号： A61K31/26 ,  A61K31/497 ,  A61K31/5517

摘要： The present invention is directed to a method of inhibiting CYP3A4 induction. The method involves administering a compound of the following formula: R1—X—(CH2)n—N═C═S with R1, X, and n defined herein, binds to a Pregnane X Receptor or Steroid and Xenobiotic Receptor (SXR or NR1I2) under conditions effective to inhibit CYP3A4 gene induction. The present invention also include a method of administering a compound, described herein, together with the CYP3A4 inducer to prevent a loss of efficacy in the subject to whom the CYP3A4 inducer is repeatedly administered. In addition, such compounds can be administered to block the interaction between a CYP3A4 inducer and another drug being administered that is a substrate of CYP3A4.

摘要翻译： 本发明涉及抑制CYP3A4诱导的方法。 该方法包括给予下式化合物：<？in-line-formula description =“In-line Formulas”end =“lead”？> R 1 -X-（CH） ＆lt; N＆gt; -NCS＆lt;？in-line-formula description =“In-line Formulas”end =“tail”？> R＆lt; 1＆lt; 和n定义在有效抑制CYP3A4基因诱导的条件下与妊娠X受体或类固醇和异生素受体（SXR或NR1I2）结合。 本发明还包括与CYP3A4诱导剂一起施用本文所述的化合物以防止在重复施用CYP3A4诱导物的受试者中的功效丧失的方法。 此外，可以施用这样的化合物以阻断CYP3A4诱导剂与作为CYP3A4的底物的另一种正在给药的药物之间的相互作用。

公开(公告)号：US3992329A

公开(公告)日：1976-11-16

申请号：US656360

申请日：1976-02-09

申请人： David L. Eaton ,  Ralph A. Messing

发明人： David L. Eaton ,  Ralph A. Messing

IPC分类号： C12N11/14 ,  C12P19/24 ,  B01J21/04

CPC分类号： C12N11/14 ,  C12P19/24

摘要： An efficient immobilized glucose isomerase composite can be prepared by adsorbing the enzyme within the pores of a porous inorganic support having an average pore size between about 100 A and 1000 A and consisting of about 0.84% to 12.0% MgO and 99.16% to 88.0% Al.sub.2 O.sub.3, by weight.

摘要翻译： 通过将酶吸附在平均孔径在约100A和100​​0A之间的多孔无机载体的孔内，由约0.84％至12.0％的MgO和99.16％至88.0％的Al 2 O 3组成，可以制备有效的固定化葡萄糖异构酶复合物 ，重量。

公开(公告)号：US3982997A

公开(公告)日：1976-09-28

申请号：US507209

申请日：1974-09-18

申请人： David L. Eaton ,  Ralph A. Messing

发明人： David L. Eaton ,  Ralph A. Messing

IPC分类号： C12N9/92 ,  B01J20/08 ,  C12N11/14 ,  C12P19/24 ,  C07G7/02 ,  C12D13/00

CPC分类号： C12P19/24 ,  C12N11/14

摘要： An efficient immobilized glucose isomerase composite can be prepared by adsorbing the enzyme within the pores of a porous inorganic support having an average pore size between about 100 A and 1000 A and consisting of about 0.84% to 12.0% MgO and 99.16% to 88.0% Al.sub.2 O.sub.3, by weight.

摘要翻译： 通过将酶吸附在平均孔径在约100A和100​​0A之间的多孔无机载体的孔内，由约0.84％至12.0％的MgO和99.16％至88.0％的Al 2 O 3组成，可以制备有效的固定化葡萄糖异构酶复合物 ，重量。

公开(公告)号：US07864398B2

公开(公告)日：2011-01-04

申请号：US11682098

申请日：2007-03-05

申请人： Gary J. Dozeman ,  Henry A. Luten ,  George A. Neuman ,  William L. Tonar ,  Thomas F. Guarr ,  Leroy J. Kloeppner ,  David L. Eaton

发明人： Gary J. Dozeman ,  Henry A. Luten ,  George A. Neuman ,  William L. Tonar ,  Thomas F. Guarr ,  Leroy J. Kloeppner ,  David L. Eaton

IPC分类号： G02F1/15 ,  G02F1/153

CPC分类号： G02F1/155 ,  B60R1/088 ,  B82Y20/00 ,  G02F2202/36 ,  Y10S359/90

摘要： A method for manufacturing an electrochromic element comprises providing a first substrate having first and second surfaces opposite one another and a first edge surface, providing a second substrate having third and fourth surfaces opposite one another and a second edge surface, wherein the third surfaces faces the second surface, and providing an electrochromic medium located between the first and second substrates, wherein the electrochromic medium has a light transmittance that is variable upon the application of electric field thereto. The method further complies applying a conductive layer on at least a portion of at least a select one of a first, second, third, and fourth surfaces and the first and second edge surfaces, wherein applying the conductive layer is accomplished at substantially atmospheric pressure and including applying at least a select one of metallic particles, an organometallic, a metallo-organic, and combinations thereof, and wherein the conductive layer has a bulk resistivity of less than or equal to 150 μΩ·cm. Other aspects of this invention comprise applying the conductive layer via ink jetting, ultrasonic spraying, auger pumping and jet pumping.

摘要翻译： 一种制造电致变色元件的方法包括提供具有彼此相对的第一和第二表面的第一基底和第一边缘表面，提供具有彼此相对的第三和第四表面的第二基底和第二边缘表面，其中第三表面面向 并且提供位于第一和第二基板之间的电致变色介质，其中电致变色介质具有在施加电场时可变的透光率。 该方法进一步遵循在至少一部分第一，第二，第三和第四表面以及第一和第二边缘表面中的至少一部分上施加导电层，其中施加导电层是在大气压下完成的， 包括施加至少一种选择的金属颗粒，有机金属，金属有机物及其组合，并且其中导电层具有小于或等于150μΩ·cm的体电阻率。 本发明的其它方面包括通过喷墨，超声波喷涂，螺旋推送和喷射泵送来施加导电层。

公开(公告)号：US20070201122A1

公开(公告)日：2007-08-30

申请号：US11682098

申请日：2007-03-05

申请人： Gary J. Dozeman ,  Henry A. Luten ,  George A. Neuman ,  William L. Tonar ,  Thomas F. Guarr ,  Leroy J. Kloeppner ,  David L. Eaton

发明人： Gary J. Dozeman ,  Henry A. Luten ,  George A. Neuman ,  William L. Tonar ,  Thomas F. Guarr ,  Leroy J. Kloeppner ,  David L. Eaton

IPC分类号： G02F1/15

CPC分类号： G02F1/155 ,  B60R1/088 ,  B82Y20/00 ,  G02F2202/36 ,  Y10S359/90

摘要： A method for manufacturing an electrochromic element comprises providing a first substrate having first and second surfaces and a first edge surface, providing a second substrate having third and fourth surfaces and a second edge surface, the third surfaces facing the second surface, providing an electrochromic medium located between the first and second substrates, the medium having a light transmittance that is variable upon application of electric field thereto, applying a conductive layer on a portion of at least one of the surfaces, wherein applying the layer is accomplished at substantially atmospheric pressure, and applying at least one of metallic particles, an organometallic, a metallo-organic, and combinations thereof, wherein the conductive layer has a bulk resistivity of greater than or equal to 150 μΩ·cm. The conductive layer may be applied via ink jetting, ultrasonic spraying, auger or jet pumping.

摘要翻译： 一种制造电致变色元件的方法包括提供具有第一和第二表面的第一基底和第一边缘表面，提供具有第三和第四表面的第二基底和第二边缘表面，所述第三表面面向第二表面，提供电致变色介质 位于第一和第二基板之间，介质具有在施加电场时变化的透光率，在至少一个表面的一部分上施加导电层，其中施加该层是在基本上大气压下完成的， 以及施加金属颗粒，有机金属，金属有机物及其组合中的至少一种，其中所述导电层具有大于或等于150μmO·cm的体电阻率。 可以通过喷墨，超声波喷涂，螺旋钻或喷射泵送来施加导电层。

公开(公告)号：US06690029B1

公开(公告)日：2004-02-10

申请号：US10143405

申请日：2002-05-10

申请人： John E. Anthony ,  David L. Eaton ,  Sean Parkin

发明人： John E. Anthony ,  David L. Eaton ,  Sean Parkin

IPC分类号： H01L5100

CPC分类号： H01L51/0094 ,  H01L51/0055 ,  H01L51/0545 ,  Y02E10/549

摘要： Novel substituted pentacenes and electronic devices made with those substituted pentacenes are disclosed.

摘要翻译： 公开了用那些取代的五苯制备的新型取代并五苯和电子器件。

公开(公告)号：US4483623A

公开(公告)日：1984-11-20

申请号：US485476

申请日：1983-04-15

申请人： David L. Eaton ,  William P. Vann

发明人： David L. Eaton ,  William P. Vann

IPC分类号： B01F13/08 ,  B01F7/18

CPC分类号： B01F13/0827

摘要： An improved magnetic stirring apparatus capable of suspending solids in a liquid medium comprising: a vessel for containing fluids and solids, having walls, a bottom, and an opening; a stirrer having a magnetic impeller and a shaft, a means for rotating the magnetic impeller; and a closure; wherein the improvement is characterized by:(a) the shaft having;(i) an upper portion; and(ii) a narrower lower portion; an upper bearing surface being formed where the lower portion extends outwardly to the upper portion;(b) an elongated shaft support member which(i) is attached to the closure; and(ii) has an aperture dimensioned and configured to receive the lower shaft portion and allow free rotation, opposed aperture margins forming a lower bearing surface; and(c) a sling bearing formed by the upper bearing surface engaging the lower bearing surface in the direction of the vessel bottom, thereby suspending the stirrer.

摘要翻译： 一种能够将固体悬浮在液体介质中的改进的磁力搅拌装置，包括：用于容纳流体和固体的容器，具有壁，底部和开口; 具有磁性叶轮和轴的搅拌器，用于旋转磁性叶轮的装置; 和封闭; 其特征在于：（a）所述轴具有： （i）上部; 和（ii）较窄的下部; 形成上部支承表面，其中下部向外延伸到上部; （b）细长轴支撑构件，其（i）附接到所述封闭件; 和（ii）具有尺寸和构造成容纳下轴部分并允许自由旋转的孔，孔对置形成下支承面; 和（c）由所述上轴承表面在所述容器底部的方向上接合所述下支承表面形成的吊索轴承，从而悬挂所述搅拌器。