Solvent systems for pour-on formulations for combating parasites
    3.
    发明授权
    Solvent systems for pour-on formulations for combating parasites 有权
    用于防治寄生虫的倾注配方的溶剂体系

    公开(公告)号:US08097266B2

    公开(公告)日:2012-01-17

    申请号:US12324066

    申请日:2008-11-26

    IPC分类号: A01N25/02

    摘要: This invention relates to pharmaceutical and veterinary formulations providing enhanced solvency and stability for pharmaceutical and veterinary agents for administration to animals, especially ruminants. In addition, the invention relates to pour-on formulations for combating parasites in animals, such as cattle and sheep. In some embodiments, this invention provides glycol-ether-based pour-on formulations comprising a composition comprising a flukicide, such as, for example, clorsulon (4-amino-6-trichloroethenyl-1,3-benzene disulfonamide) and/or a macrolide anthelmintic or antiparasitic agent. In other embodiments, the invention provides pour-on formulations comprising at least one active agent, a glycol ether, and a stability enhancer. This invention also provides for methods for eradicating, controlling, and/or preventing parasite infestation in animals, such as cattle and sheep.

    摘要翻译: 本发明涉及药物和兽用制剂,其为动物,特别是反刍动物施用药物和兽药提供增强的溶解能力和稳定性。 此外,本发明涉及用于防治动物如牛和绵羊中的寄生虫的倾注制剂。 在一些实施方案中,本发明提供了包含含有例如克隆(4-氨基-6-三氯乙烯基-1,3-苯二磺酰胺)和/或 大环内酯类驱虫剂或抗寄生虫剂。 在其它实施方案中,本发明提供了包含至少一种活性剂,二醇醚和稳定性增强剂的浇注制剂。 本发明还提供了用于消灭,控制和/或预防动物如牛和绵羊中的寄生虫侵袭的方法。

    HIV-encoded chemoattractant
    5.
    发明申请

    公开(公告)号:US20050158341A1

    公开(公告)日:2005-07-21

    申请号:US11078729

    申请日:2005-03-14

    摘要: The combination of HIV proteins Tat and Nef is chemotactic for CD4+ cells. Utilizing the capacity of Tat and Nef to modulate CD4+ cell trafficking and infiltration, the invention provides various treatment modes for individuals infected with HIV. The invention further provides treatment modes for other localized diseases by controlling CD4+ cell trafficking and infiltration. In particular, the invention provides methodology for promoting CD4+ cell chemotaxis to a localized site of infection as a means of augmenting the efficacy of extant chemotherapeutic methods. The invention further provides methodology for diverting CD4+ cell infiltration from a localized site where the presence of CD4+ cells is detrimental to the clinical outcome, by providing a composition comprising Tat and Nef at a distinct site, such as blood, within the individual where the accumulation of CD4+ cells is less detrimental.

    INSECTICIDAL 4-AMINO-THIENO[2,3-D]-PYRIMIDINE COMPOUNDS AND METHODS OF THEIR USE
    8.
    发明申请
    INSECTICIDAL 4-AMINO-THIENO[2,3-D]-PYRIMIDINE COMPOUNDS AND METHODS OF THEIR USE 有权
    杀虫剂4-氨基 - 噻吩并[2,3-D] - 嘧啶化合物及其使用方法

    公开(公告)号:US20120252667A1

    公开(公告)日:2012-10-04

    申请号:US13386194

    申请日:2010-07-29

    摘要: Insecticidal 4-Amino-thieno[2,3-d]-pyrimidine compounds and methods of their use to control pests that damage plants and crops and parasites that harm animals.The present invention relates to new insecticidal 4-Amino-thieno[2,3-d]-pyrimidine compounds and new methods of their use.The new 4-Amino-thieno[2,3-d]-pyrimidine derivatives have the general formula I: wherein X, R1, R2, R3 and A are defined as in the description.The invention relates also to their enantiomer, diastereomer or agriculturally or veterinary acceptable salt thereof. The invention relates also to agricultural and veterinary compositions comprising such compounds. The invention relates further also to different insecticidal methods applying such compounds and compositions.

    摘要翻译: 杀虫剂4-氨基 - 噻吩并[2,3-d] - 嘧啶化合物及其用于控制​​害虫损害动物的植物和作物和寄生虫的方法。 本发明涉及新的杀虫剂4-氨基 - 噻吩并[2,3-d] - 嘧啶化合物及其使用的新方法。 新的4-氨基 - 噻吩并[2,3-d] - 嘧啶衍生物具有通式I:其中X,R 1,R 2,R 3和A如描述中所定义。 本发明还涉及它们的对映异构体,非对映异构体或农业上或兽医学上可接受的盐。 本发明还涉及包含这种化合物的农业和兽用组合物。 本发明还涉及应用这种化合物和组合物的不同杀虫方法。