利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

9 条记录 (耗时 0.021 秒)

    Stimulation of hematopoiesis by ex vivo activated immune cells
    2.
    发明授权
    Stimulation of hematopoiesis by ex vivo activated immune cells 有权

    公开(公告)号：US07048922B2

    公开(公告)日：2006-05-23

    申请号：US10159148

    申请日：2002-05-29

    申请人： Demao Yang

    发明人： Demao Yang

    IPC分类号： A61K35/14 ,  C07K14/475 ,  C07K14/55

    CPC分类号： C12N5/0634 ,  A61K35/14 ,  C12N2500/14 ,  C12N2501/22 ,  C12N2501/23

    摘要： A protocol of activating and administering human blood cells so that bone marrow histology and/or blood cell counts of patients suffering from aplastic anemia approach normal. The protocol includes culturing the blood cells in the presence of a cytokine and an ionophore. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. 37 C.F.R. § 1.72(b).

    Compositions and treatments using ex vivo activated cells for myelosuppressed patients
    3.
    发明申请
    Compositions and treatments using ex vivo activated cells for myelosuppressed patients 审中-公开
    使用骨髓抑制患者的离体活化细胞的组合和治疗

    公开(公告)号：US20060057121A1

    公开(公告)日：2006-03-16

    申请号：US10939302

    申请日：2004-09-10

    申请人： Demao Yang

    发明人： Demao Yang

    IPC分类号： A61K35/14 ,  C12N5/08

    CPC分类号： C12N5/0634 ,  A61K2035/124 ,  C12N2500/14 ,  C12N2501/22 ,  C12N2501/23

    摘要： The disclosure includes protocols for activating and administering human blood cells to severely myelosuppressed patients, including patients treated for cancer, e.g., by chemotherapy or radiation. The protocol may include culturing blood cells in the presence of activating agents, for example, a cytokine and an ionophore.

    摘要翻译： 本公开包括用于激活和给予严重骨髓抑制患者的人血细胞的方案，包括例如通过化疗或放射治疗癌症的患者。 方案可以包括在活化剂例如细胞因子和离子载体存在下培养血细胞。

    Stimulation of hematopoiesis by ex vivo activated immune cells
    4.
    发明申请
    Stimulation of hematopoiesis by ex vivo activated immune cells 审中-公开
    通过离体活化的免疫细胞刺激造血

    公开(公告)号：US20050130303A1

    公开(公告)日：2005-06-16

    申请号：US10984183

    申请日：2004-11-09

    申请人： Demao Yang

    发明人： Demao Yang

    IPC分类号： A61K35/12 ,  A61K35/14 ,  C12N5/078 ,  A61K45/00 ,  C12N5/08

    CPC分类号： C12N5/0634 ,  A61K35/14 ,  C12N2500/14 ,  C12N2501/22 ,  C12N2501/23

    摘要： A protocol of activating and administering human blood cells so that bone marrow histology and/or blood cell counts of patients suffering from a plastic anemia approach normal. The protocol includes culturing the blood cells in the presence of a cytokine and an ionophore. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. 37 C.F.R. § 1.72(b).

    摘要翻译： 激活和施用人类血细胞的方案，使得患有塑性贫血的患者的骨髓组织学和/或血细胞计数正常。 方案包括在细胞因子和离子载体存在下培养血细胞。 要强调的是，该摘要被提供以符合要求抽象的规则，允许搜索者或其他读者快速确定技术公开内容的主题。 提交它的理解是，它不会用于解释或限制权利要求的范围或含义。 37 C.F.R. §1.72（b）。

    CELL THERAPY FOR PATIENTS
    5.
    发明申请
    CELL THERAPY FOR PATIENTS 审中-公开

    公开(公告)号：US20190298766A1

    公开(公告)日：2019-10-03

    申请号：US15940553

    申请日：2018-03-29

    申请人： Demao Yang

    发明人： Demao Yang

    IPC分类号： A61K35/17 ,  A61P3/10 ,  A61B5/145

    摘要： Materials and methods of treating a patient with type 2 diabetes mellitus, metabolic syndrome, obesity, infertility, high blood pressure, hyperthyroidism, and hypothyroidism, hyperlipidaemia, osteoporosis, osteoarthritis, hypoadrenalism, polycystic ovary syndrome, or Parkinson's disease comprising administering a therapeutically effective amount of ex vivo cultured activated peripheral blood mononuclear cells (PBMCs) to the patient. The ex vivo cultured activated cells are activated and cultured in a presence of a cytokine and may be autologous or allogeneic relative to the patient.

    Stimulation of hematopoiesis by ex vivo activated immune cells
    6.
    发明授权
    Stimulation of hematopoiesis by ex vivo activated immune cells 失效
    通过离体活化的免疫细胞刺激造血

    公开(公告)号：US07758857B2

    公开(公告)日：2010-07-20

    申请号：US12220989

    申请日：2008-07-30

    申请人： Demao Yang

    发明人： Demao Yang

    IPC分类号： A61K35/14 ,  C07K14/475 ,  C07K14/55

    CPC分类号： C12N5/0634 ,  A61K35/14 ,  C12N2500/14 ,  C12N2501/22 ,  C12N2501/23

    摘要： A protocol of activating and administering human blood cells so that bone marrow histology and/or blood cell counts of patients suffering from a plastic anemia approach normal. The protocol includes culturing the blood cells in the presence of a cytokine and an ionophore. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. 37 C.F.R. §1.72(b).

    摘要翻译： 激活和施用人类血细胞的方案，使得患有塑性贫血的患者的骨髓组织学和/或血细胞计数正常。 方案包括在细胞因子和离子载体存在下培养血细胞。 要强调的是，该摘要被提供以符合要求抽象的规则，允许搜索者或其他读者快速确定技术公开内容的主题。 提交它的理解是，它不会用于解释或限制权利要求的范围或含义。 37 C.F.R. §1.72（b）。

    Materials for stimulation of hematopoiesis by ex vivo activated cells
    7.
    发明申请
    Materials for stimulation of hematopoiesis by ex vivo activated cells 失效
    用于通过离体活化细胞刺激造血的材料

    公开(公告)号：US20080292605A1

    公开(公告)日：2008-11-27

    申请号：US12220989

    申请日：2008-07-30

    申请人： Demao Yang

    发明人： Demao Yang

    IPC分类号： A61K35/12 ,  A61P7/00

    CPC分类号： C12N5/0634 ,  A61K35/14 ,  C12N2500/14 ,  C12N2501/22 ,  C12N2501/23

    摘要： A protocol of activating and administering human blood cells so that bone marrow histology and/or blood cell counts of patients suffering from a plastic anemia approach normal. The protocol includes culturing the blood cells in the presence of a cytokine and an ionophore. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.

    摘要翻译： 激活和施用人类血细胞的方案，使得患有塑性贫血的患者的骨髓组织学和/或血细胞计数正常。 方案包括在细胞因子和离子载体存在下培养血细胞。 要强调的是，该摘要被提供以符合要求抽象的规则，允许搜索者或其他读者快速确定技术公开内容的主题。 提交它的理解是，它不会用于解释或限制权利要求的范围或含义。