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1.发明授权Calibration of pulse transit time measurements to arterial blood pressure using external arterial pressure applied along the pulse transit path 有权使用沿脉冲传输路径施加的外部动脉压力校准脉搏传播时间测量与动脉血压公开(公告)号：US08313439B2
公开(公告)日：2012-11-20
申请号：US12408345
申请日：2009-03-20
IPC分类号： A61B5/02
CPC分类号： A61B5/021 , A61B5/02125
摘要： An apparatus and methods for adaptive and autonomous calibration of pulse transit time measurements to obtain arterial blood pressure using arterial pressure variation. The apparatus and methods give pulse transit time (PTT) devices an ability to self-calibrate. The methods apply a distributed model with lumped parameters, and may be implemented, for example, using pulse transit time measurements derived from a wearable photoplethysmograph (PPG) sensor architecture with an intervening pressurizing mechanism.
摘要翻译： 用于自适应和自主校准脉冲传播时间测量以使用动脉压变化获得动脉血压的装置和方法。 该装置和方法使脉冲传播时间（PTT）装置具有自校准能力。 该方法应用具有集总参数的分布式模型，并且可以例如使用来自具有中间加压机构的可穿戴光电体积描记器（PPG）传感器结构的脉冲传播时间测量来实现。
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2.发明申请Calibration of Pulse Transit Time Measurements to Arterial Blood Pressure using External Arterial Pressure Applied along the Pulse Transit Path 有权使用沿脉冲传输路径施加的外部动脉压进行脉搏转移时间测量的动脉血压校准公开(公告)号：US20100241011A1
公开(公告)日：2010-09-23
申请号：US12408345
申请日：2009-03-20
IPC分类号： A61B5/02
CPC分类号： A61B5/021 , A61B5/02125
摘要： An apparatus and methods for adaptive and autonomous calibration of pulse transit time measurements to obtain arterial blood pressure using arterial pressure variation. The apparatus and methods give pulse transit time (PTT) devices an ability to self-calibrate. The methods apply a distributed model with lumped parameters, and may be implemented, for example, using pulse transit time measurements derived from a wearable photoplethysmograph (PPG) sensor architecture with an intervening pressurizing mechanism.
摘要翻译： 用于自适应和自动校准脉冲传播时间测量以使用动脉压变化获得动脉血压的装置和方法。 该装置和方法使脉冲传播时间（PTT）装置具有自校准能力。 该方法应用具有集总参数的分布式模型，并且可以例如使用来自具有中间加压机构的可穿戴光电体积描记器（PPG）传感器结构的脉冲传播时间测量来实现。
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3.发明授权Wearable pulse wave velocity blood pressure sensor and methods of calibration thereof 有权穿戴式脉搏波速度血压传感器及其校准方法公开(公告)号：US07674231B2
公开(公告)日：2010-03-09
申请号：US11840654
申请日：2007-08-17
IPC分类号： A61B5/02
CPC分类号： A61B5/02255 , A61B5/02125 , A61B5/7239
摘要： An apparatus and methods for performing a circulatory measurement on an extremity, such as a hand, of a subject. The circulatory measurement results in the derivation of an output circulatory metric that may encompass blood pressure or various other circulatory metrics. An indicator of an input circulatory metric at a locus on the extremity is measured, such as a pulse transit time, and calibrated to account for the hydrostatic component of blood pressure arising due to vertical displacement of the extremity with respect to the heart.
摘要翻译： 用于对受试者的肢体（例如手）进行循环测量的装置和方法。 循环测量结果导出可包含血压或各种其他循环指标的输出循环指标。 测量在肢体上的轨迹上的输入循环度量的指标，例如脉冲传播时间，并且被校准以考虑由于肢体相对于心脏的垂直位移而产生的血压的静水分量。
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公开(公告)号：US07641614B2
公开(公告)日：2010-01-05
申请号：US11508123
申请日：2006-08-22
IPC分类号： A61B5/00
CPC分类号： A61B5/02255 , A61B5/02225 , A61B5/02233 , A61B5/11 , A61B5/6824 , A61B5/6826 , A61B5/6838 , A61B2562/0219
摘要： Methods and apparatus for measuring arterial blood pressure at an extremity of a subject. Arterial blood pressure is derived from a circulatory measurement performed on an extremity of a subject and the circulatory measurement is normalized to account for the instantaneous vertical displacement of the extremity. The vertical displacement of the extremity relative to the heart of the subject is obtained using the angular orientation of the subject's extremity. An improved photoplethysmograph can discriminate light traversing the extremity from ambient light on the basis of differential response. The apparatus may have a conducting polymer actuator for applying pressure to the extremity of the subject. A pulsatile waveform from the photoplethysmographic signal may be obtained at a plurality of externally applied pressures to calibrate the photoplethysmograph.
摘要翻译： 用于测量受试者末端动脉血压的方法和装置。 动脉血压来源于在受试者的肢体上进行的循环测量，循环测量被归一化以考虑肢体的瞬时垂直位移。 使用受试者肢体的角度取向获得肢体相对于受试者心脏的垂直位移。 改进的光电容积法可以根据差异响应来区分穿过末端的光与环境光。 该装置可以具有用于向受试者的末端施加压力的导电聚合物致动器。 可以在多个外部施加的压力下获得来自光电体积描记信号的脉动波形，以校准光谱体积描记器。
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