公开(公告)号：US06402369B1

公开(公告)日：2002-06-11

申请号：US09432736

申请日：1999-11-02

申请人： David Norman Ludington ,  Thomas Louis Fare ,  Dominic Joseph Lo Iacono ,  Timothy James Davis ,  Helen Jiang Semus ,  Paul John Stabile ,  Frank Guarnieri ,  Russell Todd Granzow ,  Peter J. Zanzucchi ,  William Chiang

发明人： David Norman Ludington ,  Thomas Louis Fare ,  Dominic Joseph Lo Iacono ,  Timothy James Davis ,  Helen Jiang Semus ,  Paul John Stabile ,  Frank Guarnieri ,  Russell Todd Granzow ,  Peter J. Zanzucchi ,  William Chiang

IPC分类号： G01N2500

CPC分类号： G01N25/482 ,  B01J2219/00317 ,  B01J2219/00495 ,  B01J2219/00659 ,  B01J2219/00707 ,  C40B60/14 ,  G01N25/4866

摘要： Provided are, among other things, devices for and methods for performing thermal signature assays on a two or more samples in an array, using active/control base thermopiles, the method comprising: [a] performing a heat transfer to the two or more samples in each of a two or more containers, using at least one base thermopile in thermal communication with the two or more containers; and [b] determining a total heat transferred to the samples by the base thermopile in step [a]; and [c] sensing in real time a temperature difference between a first sample and a second sample of the two or more samples resulting from performing step [a].

摘要翻译： 提供了尤其是用于使用主动/控制基热电堆在阵列中的两个或更多个样品上执行热特征测定的装置和方法，所述方法包括：[a]对所述两个或更多个样品进行热传递 在两个或更多个容器中的每一个中，使用与两个或更多个容器热连通的至少一个基座热电堆; 和[b]在步骤[a]中确定由基础热电堆转移到样品的总热量; 和[c]实时检测由执行步骤[a]得到的两个或多个样品的第一样品和第二样品之间的温度差。