公开(公告)号：US20120282334A1

公开(公告)日：2012-11-08

申请号：US13290361

申请日：2011-11-07

Applicant: Dong Bin Shin ,  Mi Young Yoo ,  Ho Moon Seog ,  Jae Ho Ha ,  Sang Hee Lee ,  Yong Sun Cho

Inventor： Dong Bin Shin ,  Mi Young Yoo ,  Ho Moon Seog ,  Jae Ho Ha ,  Sang Hee Lee ,  Yong Sun Cho

IPC: A61K9/48 ,  A61J3/07 ,  C07C323/65 ,  C07C319/28 ,  A61K31/105

CPC classification number: C07C319/28 ,  A23L33/105 ,  A23L33/115 ,  A23P10/30 ,  A61K31/105 ,  A61K35/20 ,  A61K36/8962 ,  A61K2236/00 ,  C07C323/65

Abstract: Disclosed is a method for preparing ajoene including: (a) obtaining garlic pulp or garlic extract from garlic; (b) mixing the garlic pulp or garlic extract with animal lipid to form a reaction mixture; and (c) heating the reaction mixture to obtain ajoene. The ajoene prepared according to the present disclosure may be encapsulated with gelatin. According to the present disclosure, ajoene can be prepared with a yield 2 times or more than that of the existing methods. Thus, ajoene can be provided as active ingredient for foods and medicines more cost-effectively. Also, the production protocol according to the present disclosure is suitable for large-scale production of ajoene.

Abstract translation: 公开了一种制备方法，包括：（a）从大蒜获得大蒜纸浆或大蒜提取物; （b）将大蒜纸浆或大蒜提取物与动物脂质混合以形成反应混合物; 和（c）加热反应混合物以获得乙烯。 根据本公开制备的阿jo烯可以用明胶包封。 根据本公开，可以以现有方法的2倍以上的产量制备ajoene。 因此，作为食品和药物的有效成分，可以更具成本效益。 此外，根据本公开的生产方案适用于大规模生产。